GB2009731A - Pyrido [3,2,1-jk] carbazol derivative - Google Patents

Pyrido [3,2,1-jk] carbazol derivative

Info

Publication number
GB2009731A
GB2009731A GB7843756A GB7843756A GB2009731A GB 2009731 A GB2009731 A GB 2009731A GB 7843756 A GB7843756 A GB 7843756A GB 7843756 A GB7843756 A GB 7843756A GB 2009731 A GB2009731 A GB 2009731A
Authority
GB
United Kingdom
Prior art keywords
group
pyrido
formula
image
halogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7843756A
Other versions
GB2009731B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Publication of GB2009731A publication Critical patent/GB2009731A/en
Application granted granted Critical
Publication of GB2009731B publication Critical patent/GB2009731B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Abstract

A pyrido [3,2,1-jk] carbazol derivative is represented by the formula (I> <IMAGE> wherein R represents a hydroxy group, an alkoxy group which may be substituted with a halogen atom or with a 4-methyl-1-piperizinyl group, a hydrazino group or a <IMAGE> group, Y represents an alkoxy group, a halogen atom, a nitro group, an amino group, an alkanoylamino group or alkyl group, and n is 0, 1 or 2. The compound of formula (I) and the pharmaceutically acceptable salts thereof have antimicrobial, anti-cancer and antiviral activities.
GB7843756A 1977-11-15 1978-11-08 Pyrido(3,2,1-jk)carbazol derivatives Expired GB2009731B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52137418A JPS584717B2 (en) 1977-11-15 1977-11-15 Pyrido[3,2,1-jk]carbazole derivative

Publications (2)

Publication Number Publication Date
GB2009731A true GB2009731A (en) 1979-06-20
GB2009731B GB2009731B (en) 1982-05-12

Family

ID=15198157

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7843756A Expired GB2009731B (en) 1977-11-15 1978-11-08 Pyrido(3,2,1-jk)carbazol derivatives

Country Status (10)

Country Link
JP (1) JPS584717B2 (en)
BE (1) BE872000A (en)
CA (1) CA1122984A (en)
CH (1) CH638808A5 (en)
DE (1) DE2849158A1 (en)
FR (1) FR2408606A1 (en)
GB (1) GB2009731B (en)
IT (1) IT1111363B (en)
NL (1) NL7811239A (en)
SE (1) SE437519B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS588396B2 (en) * 1978-08-11 1983-02-15 大塚製薬株式会社 Pyrido[3,2,1↓-jk]carbazole derivative
US4380543A (en) * 1981-11-06 1983-04-19 Riker Laboratories, Inc. Antimicrobial 8-cyano-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE793524A (en) * 1971-12-30 1973-06-29 Riker Laboratories Inc BENZOQUINOLIZINE-CARBOXYLIC ACIDS AND THEIR DERIVATIVES
US3917609A (en) * 1973-06-27 1975-11-04 Minnesota Mining & Mfg Pyrroloquinoline carboxylic acids and derivatives

Also Published As

Publication number Publication date
GB2009731B (en) 1982-05-12
SE437519B (en) 1985-03-04
SE7811762L (en) 1979-05-16
NL7811239A (en) 1979-05-17
IT7851875A0 (en) 1978-11-13
JPS5473797A (en) 1979-06-13
JPS584717B2 (en) 1983-01-27
BE872000A (en) 1979-05-14
CH638808A5 (en) 1983-10-14
IT1111363B (en) 1986-01-13
DE2849158A1 (en) 1979-05-17
CA1122984A (en) 1982-05-04
FR2408606B1 (en) 1981-07-03
FR2408606A1 (en) 1979-06-08

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee