GB2002631A - Extracting phospholipids from animal organs - Google Patents

Extracting phospholipids from animal organs

Info

Publication number
GB2002631A
GB2002631A GB7830177A GB7830177A GB2002631A GB 2002631 A GB2002631 A GB 2002631A GB 7830177 A GB7830177 A GB 7830177A GB 7830177 A GB7830177 A GB 7830177A GB 2002631 A GB2002631 A GB 2002631A
Authority
GB
United Kingdom
Prior art keywords
phospholipids
stage
acetone
organs
animal organs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7830177A
Other versions
GB2002631B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AESCULAPIUS LAB CHIM FARMA
Original Assignee
AESCULAPIUS LAB CHIM FARMA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AESCULAPIUS LAB CHIM FARMA filed Critical AESCULAPIUS LAB CHIM FARMA
Publication of GB2002631A publication Critical patent/GB2002631A/en
Application granted granted Critical
Publication of GB2002631B publication Critical patent/GB2002631B/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Phospholipid compositions are obtained from ground. homogenised animal organs by a four stage process. in the first stage the organs are soaked in acetone to sever bonds between phospholipids and other substances present in the organ. In the second stage, the organs are refluxed in acetone to remove extraneous matter such as proteins and amino acids. In the third stage, the phospholipids are extracted with ethanol. The acetone solutions, which may contain small amounts of entrained phospholipids, and the ethanol solution are all evaporated to dryness and the residues are taken up in diethyl ether. In the fourth stage the phospholipids are precipitated by addition of acetone. The phospholipid compositions obtained are of sufficient purity for pharmaceutical use.
GB7830177A 1977-08-04 1978-07-18 Phospholipid compositions Expired GB2002631B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT26475/77A IT1085693B (en) 1977-08-04 1977-08-04 EXTRACTIVE PROCESS FOR THE PREPARATION OF PHOSPHOLIPIDES FROM ANIMALS, FOR THERAPEUTIC USE

Publications (2)

Publication Number Publication Date
GB2002631A true GB2002631A (en) 1979-02-28
GB2002631B GB2002631B (en) 1982-03-10

Family

ID=11219595

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7830177A Expired GB2002631B (en) 1977-08-04 1978-07-18 Phospholipid compositions

Country Status (4)

Country Link
ES (1) ES472267A1 (en)
FR (1) FR2399251A1 (en)
GB (1) GB2002631B (en)
IT (1) IT1085693B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888324A (en) * 1985-10-01 1989-12-19 Angio-Medical Corporation Method for enhancing angiogenesis with lipid containing molecules
US4950656A (en) * 1987-02-17 1990-08-21 Board Of Regents, The University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for protecting the gastrointestinal tract
US5032585A (en) * 1987-02-17 1991-07-16 Board Of Regents, The University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for surfactant replacement therapy
US5043329A (en) * 1987-02-17 1991-08-27 Board Of Regents, University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for protecting the gastrointestinal tract
US5260284A (en) * 1987-02-17 1993-11-09 Board Of Regents, The University Of Texas System Methods employing unique mixtures of polar and neutral lipids and sterol for lung surfactant replacement therapy

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD130Z (en) * 2009-10-22 2010-11-30 Институт Микробиологии И Биотехнологии Академии Наук Молдовы Process for obtaining a phospholipid complex from Spirulina platensis biomass
RU2493861C1 (en) * 2012-10-03 2013-09-27 Закрытое акционерное общество "Институт экспериментальной фармакологии" Biologically active complex possessing anti-allergic action

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH140867A (en) * 1928-04-11 1930-06-30 Chem Ind Basel Process for the comminution of animal components.
AT333437B (en) * 1974-02-07 1976-11-25 Etapharm Chem Pharm Lab Ges M PROCESS FOR PRODUCING PHOSPHATIDE COMPLEX WITH INCREASED PHOSPHATIDYLATHANOLAMINE CONTENT FROM ANIMAL MATERIAL

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888324A (en) * 1985-10-01 1989-12-19 Angio-Medical Corporation Method for enhancing angiogenesis with lipid containing molecules
US4950656A (en) * 1987-02-17 1990-08-21 Board Of Regents, The University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for protecting the gastrointestinal tract
US5032585A (en) * 1987-02-17 1991-07-16 Board Of Regents, The University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for surfactant replacement therapy
US5043329A (en) * 1987-02-17 1991-08-27 Board Of Regents, University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for protecting the gastrointestinal tract
US5260284A (en) * 1987-02-17 1993-11-09 Board Of Regents, The University Of Texas System Methods employing unique mixtures of polar and neutral lipids and sterol for lung surfactant replacement therapy

Also Published As

Publication number Publication date
GB2002631B (en) 1982-03-10
ES472267A1 (en) 1979-10-01
FR2399251A1 (en) 1979-03-02
IT1085693B (en) 1985-05-28

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Legal Events

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