GB2001069A - Therapeutic pyrimidine derivatives - Google Patents

Therapeutic pyrimidine derivatives

Info

Publication number
GB2001069A
GB2001069A GB7829550A GB7829550A GB2001069A GB 2001069 A GB2001069 A GB 2001069A GB 7829550 A GB7829550 A GB 7829550A GB 7829550 A GB7829550 A GB 7829550A GB 2001069 A GB2001069 A GB 2001069A
Authority
GB
United Kingdom
Prior art keywords
image
therapeutic
derivatives
pyrimidine derivatives
atheromatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7829550A
Other versions
GB2001069B (en
Inventor
Alain Beguin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority to GB7829550A priority Critical patent/GB2001069B/en
Publication of GB2001069A publication Critical patent/GB2001069A/en
Application granted granted Critical
Publication of GB2001069B publication Critical patent/GB2001069B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The derivatives have the general formula <IMAGE> in which <IMAGE> and have anti-atheromatic activity. The derivatives may be prepared by reacting piperidine or piperazine RH is reacted with the corresponding chloride: <IMAGE> in which the 3-OH and 4-CH2OH groups of the pyridoxine ring have been blocked. The reaction takes place under reflux in a polar solvent, and the blocking group is subsequently removed.
GB7829550A 1977-07-12 1978-07-12 Pyrimidine derivatives Expired GB2001069B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB7829550A GB2001069B (en) 1977-07-12 1978-07-12 Pyrimidine derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2928177 1977-07-12
GB7829550A GB2001069B (en) 1977-07-12 1978-07-12 Pyrimidine derivatives

Publications (2)

Publication Number Publication Date
GB2001069A true GB2001069A (en) 1979-01-24
GB2001069B GB2001069B (en) 1982-01-20

Family

ID=26259846

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7829550A Expired GB2001069B (en) 1977-07-12 1978-07-12 Pyrimidine derivatives

Country Status (1)

Country Link
GB (1) GB2001069B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7759357B2 (en) 2002-02-01 2010-07-20 Novartis Ag Phenylpyrimidine amines as IgE inhibitors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7759357B2 (en) 2002-02-01 2010-07-20 Novartis Ag Phenylpyrimidine amines as IgE inhibitors

Also Published As

Publication number Publication date
GB2001069B (en) 1982-01-20

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Legal Events

Date Code Title Description
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee