GB1566154A - Method of measuring the fluidity of liquids for medical and pharmaceutical pruposes and apparatus for performing the method - Google Patents
Method of measuring the fluidity of liquids for medical and pharmaceutical pruposes and apparatus for performing the method Download PDFInfo
- Publication number
- GB1566154A GB1566154A GB11318/77A GB1131877A GB1566154A GB 1566154 A GB1566154 A GB 1566154A GB 11318/77 A GB11318/77 A GB 11318/77A GB 1131877 A GB1131877 A GB 1131877A GB 1566154 A GB1566154 A GB 1566154A
- Authority
- GB
- United Kingdom
- Prior art keywords
- liquid
- measuring
- capillary tube
- tube
- reservoir unit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000007788 liquid Substances 0.000 title claims description 115
- 238000000034 method Methods 0.000 title claims description 29
- 210000004369 blood Anatomy 0.000 claims description 40
- 239000008280 blood Substances 0.000 claims description 40
- 238000005259 measurement Methods 0.000 claims description 37
- 239000000872 buffer Substances 0.000 claims description 24
- 239000003978 infusion fluid Substances 0.000 claims description 12
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims description 12
- 239000004952 Polyamide Substances 0.000 claims description 7
- 229920002647 polyamide Polymers 0.000 claims description 7
- 229910052697 platinum Inorganic materials 0.000 claims description 6
- 229910001220 stainless steel Inorganic materials 0.000 claims description 6
- 239000010935 stainless steel Substances 0.000 claims description 6
- 210000002966 serum Anatomy 0.000 claims description 5
- 239000013013 elastic material Substances 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 210000004027 cell Anatomy 0.000 description 18
- 238000004519 manufacturing process Methods 0.000 description 10
- 230000008901 benefit Effects 0.000 description 6
- 230000015271 coagulation Effects 0.000 description 6
- 238000005345 coagulation Methods 0.000 description 6
- 238000010276 construction Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 238000011282 treatment Methods 0.000 description 5
- 239000000463 material Substances 0.000 description 4
- 239000003570 air Substances 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 238000001802 infusion Methods 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 238000007792 addition Methods 0.000 description 2
- 230000000994 depressogenic effect Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 241001012508 Carpiodes cyprinus Species 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000012080 ambient air Substances 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000003633 blood substitute Substances 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- VNNRSPGTAMTISX-UHFFFAOYSA-N chromium nickel Chemical compound [Cr].[Ni] VNNRSPGTAMTISX-UHFFFAOYSA-N 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 238000013500 data storage Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000010339 medical test Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000005496 tempering Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6866—Extracorporeal blood circuits, e.g. dialysis circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/02028—Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
- A61B5/02035—Determining blood viscosity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/026—Measuring blood flow
- A61B5/0275—Measuring blood flow using tracers, e.g. dye dilution
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
- G01N11/02—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material
- G01N11/04—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture
- G01N11/08—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture by measuring pressure required to produce a known flow
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Analytical Chemistry (AREA)
- Physiology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Ecology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762613212 DE2613212C2 (de) | 1976-03-27 | 1976-03-27 | Verfahren zur Bestimmung des Fließverhaltens von Flüssigkeiten für medizinische und pharmazeutische Zwecke, sowie Vorrichtung zur Durchführung des Verfahrens |
| DE19762658799 DE2658799A1 (de) | 1976-12-24 | 1976-12-24 | Vorrichtung zur durchfuehrung eines verfahrens fuer medizinische und pharmazeutische zwecke zur bestimmung des fliessverhaltens von fluessigkeiten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1566154A true GB1566154A (en) | 1980-04-30 |
Family
ID=25770260
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB11318/77A Expired GB1566154A (en) | 1976-03-27 | 1977-03-17 | Method of measuring the fluidity of liquids for medical and pharmaceutical pruposes and apparatus for performing the method |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4165632A (enExample) |
| JP (1) | JPS534588A (enExample) |
| CH (1) | CH614046A5 (enExample) |
| FR (1) | FR2345716A1 (enExample) |
| GB (1) | GB1566154A (enExample) |
| NL (1) | NL7703231A (enExample) |
| SE (1) | SE7703449L (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2158252A (en) * | 1984-04-12 | 1985-11-06 | John Parnaby | Rheometers |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2519143A1 (fr) * | 1981-12-29 | 1983-07-01 | Elf Aquitaine | Viscosimetre operant en continu notamment a haute temperature |
| DE3218037C2 (de) * | 1982-05-13 | 1985-07-18 | Kiesewetter, Holger, Dr., 5100 Aachen | Vorrichtung zur Bestimmung von Fließeigenschaften, insbesondere der Fließschubspannung, von Suspensionen, insbesondere Blut |
| US4442704A (en) * | 1982-07-12 | 1984-04-17 | Swearingen Judson S | Viscosity meter |
| US4461830A (en) * | 1983-01-20 | 1984-07-24 | Buren Philpot V Jun | Serum fibrinogen viscosity in clinical medicine |
| US4567137A (en) * | 1983-01-20 | 1986-01-28 | Philpot Van B | Serum thrombin time in clinical medicine |
| FR2559907A1 (fr) * | 1984-02-21 | 1985-08-23 | Schlumberger Cie Dowell | Viscosimetre de section rectangulaire |
| US4574622A (en) * | 1984-03-27 | 1986-03-11 | Union Carbide Corporation | Viscometer |
| US4680957A (en) * | 1985-05-02 | 1987-07-21 | The Davey Company | Non-invasive, in-line consistency measurement of a non-newtonian fluid |
| US5140161A (en) * | 1985-08-05 | 1992-08-18 | Biotrack | Capillary flow device |
| US5164598A (en) * | 1985-08-05 | 1992-11-17 | Biotrack | Capillary flow device |
| EP0270616A4 (en) * | 1986-05-30 | 1988-10-20 | Kdl Technologies Inc | METHOD AND DEVICE FOR MEASURING THE VISCOSITY OF NATIVE BLOOD OF A MAMMAL. |
| US4793174A (en) * | 1987-10-05 | 1988-12-27 | E. I. Du Pont De Nemours And Company | Differential pressure capillary viscometer |
| DE3841312A1 (de) * | 1988-12-08 | 1990-06-13 | Bayer Ag | Kapillarviskosimeter |
| AU1279092A (en) * | 1991-02-04 | 1992-10-06 | Kensey Nash Corporation | Apparatus and method for determining viscosity of the blood of a living being |
| AU1569492A (en) * | 1991-03-04 | 1992-10-06 | Kensey Nash Corporation | Determining the instantaneous shear stress on the wall of a blood vessel |
| AU1570892A (en) * | 1991-03-04 | 1992-10-06 | Kensey Nash Corporation | Apparatus and method for determining deformability of red blood cells of a living being |
| FR2728345A1 (fr) * | 1994-12-16 | 1996-06-21 | Renault | Rheometre pour presse a injecter |
| FR2740215B1 (fr) * | 1995-10-19 | 1997-11-21 | Inst Francais Du Petrole | Methode et dispositif pour mesurer un parametre d'un fluide de densite variable |
| US5854423A (en) * | 1996-03-20 | 1998-12-29 | Venegas; Jose G. | Apparatus and method for assessment of visco-elasticity and shear adherence strength properties of blood clots |
| US5847268A (en) * | 1997-03-19 | 1998-12-08 | Ball; Dean M. | Viscosity measuring apparatus and method |
| US6450974B1 (en) | 1997-08-28 | 2002-09-17 | Rheologics, Inc. | Method of isolating surface tension and yield stress in viscosity measurements |
| US6428488B1 (en) | 1997-08-28 | 2002-08-06 | Kenneth Kensey | Dual riser/dual capillary viscometer for newtonian and non-newtonian fluids |
| US6322524B1 (en) | 1997-08-28 | 2001-11-27 | Visco Technologies, Inc. | Dual riser/single capillary viscometer |
| US6019735A (en) | 1997-08-28 | 2000-02-01 | Visco Technologies, Inc. | Viscosity measuring apparatus and method of use |
| US6322525B1 (en) | 1997-08-28 | 2001-11-27 | Visco Technologies, Inc. | Method of analyzing data from a circulating blood viscometer for determining absolute and effective blood viscosity |
| US6402703B1 (en) * | 1997-08-28 | 2002-06-11 | Visco Technologies, Inc. | Dual riser/single capillary viscometer |
| US6196058B1 (en) | 1998-03-12 | 2001-03-06 | Consolidated Papers, Inc. | On-line viscosity measurement system |
| US6484565B2 (en) | 1999-11-12 | 2002-11-26 | Drexel University | Single riser/single capillary viscometer using mass detection or column height detection |
| US6692437B2 (en) | 1999-11-12 | 2004-02-17 | Rheologics, Inc. | Method for determining the viscosity of an adulterated blood sample over plural shear rates |
| US20030158500A1 (en) * | 1999-11-12 | 2003-08-21 | Kenneth Kensey | Decreasing pressure differential viscometer |
| EP1134575A1 (en) * | 2000-03-07 | 2001-09-19 | Consolidated Papers, Inc. | On-line viscosity measurement system |
| US6412336B2 (en) | 2000-03-29 | 2002-07-02 | Rheologics, Inc. | Single riser/single capillary blood viscometer using mass detection or column height detection |
| US6484566B1 (en) | 2000-05-18 | 2002-11-26 | Rheologics, Inc. | Electrorheological and magnetorheological fluid scanning rheometer |
| AU2001279058A1 (en) | 2000-08-01 | 2002-02-13 | Rheologics, Inc. | Apparatus and methods for comprehensive blood analysis, including work of, and contractility of, heart and therapeutic applications and compositions thereof |
| FR2815411B1 (fr) * | 2000-10-13 | 2002-12-20 | Suez Lyonnaise Des Eaux | Dispositif de mesure des caracteristiques rheologiques de solutions concentres, de gels ou de suspensions, notamment de boues mises en oeuvre dans le traitement de l'eau |
| FR2815412B1 (fr) * | 2000-10-13 | 2003-02-14 | Ondeo Services | Dispositif de mesure des caracteristiques rheologiques de solutions concentrees, de gels ou de suspensions, notamment de boues mises en oeuvre dans le traitement de l'eau |
| US6840305B2 (en) * | 2001-04-04 | 2005-01-11 | Cannon Instrument Company | Cold cranking simulator having hybrid heat transfer system |
| AU2002355110A1 (en) * | 2001-07-18 | 2003-03-03 | Rheologics, Inc. | Single capillary tube fluid-column-over-time viscometer |
| US6792814B2 (en) * | 2002-04-10 | 2004-09-21 | Rutgers, The State University Of New Jersey | Flowmeter |
| WO2005112762A1 (en) * | 2004-05-14 | 2005-12-01 | Florida Atlantic University | Device and methods for monitoring and regulating anticoagulation therapy |
| US7634367B1 (en) | 2005-07-12 | 2009-12-15 | Ortho-Clinical Diagnostics, Inc. | Estimating fluidic properties and using them to improve the precision/accuracy of metered fluids and to improve the sensitivity/specificity in detecting failure modes |
| CN101983730B (zh) * | 2010-11-17 | 2013-02-13 | 惠州市华阳医疗电子有限公司 | 可检测伤口渗出液粘稠度的负压伤口治疗系统 |
| ITMI20110803A1 (it) * | 2011-05-10 | 2012-11-11 | Claber Spa | Impianto di irrigazione a controllo remoto. |
| JP6212682B2 (ja) * | 2014-10-14 | 2017-10-18 | 株式会社 エフ メディコ エンジ | 血液粘度測定のための流量測定装置およびその装置を利用した流量測定方法 |
| JP6887413B2 (ja) * | 2015-07-08 | 2021-06-16 | ワイアット テクノロジー コーポレイションＷｙａｔｔ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐｏｒａｔｉｏｎ | 溶媒圧縮率補正を有する示差粘度計 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3115768A (en) * | 1959-10-26 | 1963-12-31 | Standard Oil Co | Viscosimeter apparatus |
| US3720097A (en) * | 1971-01-21 | 1973-03-13 | Univ Pennsylvania | Apparatus and method for measuring mammalian blood viscosity |
| NL157424B (nl) * | 1973-03-02 | 1978-07-17 | Gist Brocades Nv | Viscosimeter. |
| DE2444148C3 (de) * | 1974-09-16 | 1981-09-17 | Dr. Karl Thomae Gmbh, 7950 Biberach | Kapillar-Viskosimeter |
| US3999538A (en) * | 1975-05-22 | 1976-12-28 | Buren Philpot V Jun | Method of blood viscosity determination |
-
1977
- 1977-03-17 GB GB11318/77A patent/GB1566154A/en not_active Expired
- 1977-03-24 CH CH372677A patent/CH614046A5/xx not_active IP Right Cessation
- 1977-03-25 JP JP3231677A patent/JPS534588A/ja active Pending
- 1977-03-25 FR FR7709851A patent/FR2345716A1/fr active Granted
- 1977-03-25 SE SE7703449A patent/SE7703449L/xx unknown
- 1977-03-25 US US05/781,475 patent/US4165632A/en not_active Expired - Lifetime
- 1977-03-25 NL NL7703231A patent/NL7703231A/xx not_active Application Discontinuation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2158252A (en) * | 1984-04-12 | 1985-11-06 | John Parnaby | Rheometers |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7703231A (nl) | 1977-09-29 |
| SE7703449L (sv) | 1977-09-28 |
| FR2345716B1 (enExample) | 1983-03-18 |
| FR2345716A1 (fr) | 1977-10-21 |
| US4165632A (en) | 1979-08-28 |
| JPS534588A (en) | 1978-01-17 |
| CH614046A5 (enExample) | 1979-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |