GB1565351A - Steroid aminoethers - Google Patents

Steroid aminoethers Download PDF

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Publication number
GB1565351A
GB1565351A GB2518775A GB2518775A GB1565351A GB 1565351 A GB1565351 A GB 1565351A GB 2518775 A GB2518775 A GB 2518775A GB 2518775 A GB2518775 A GB 2518775A GB 1565351 A GB1565351 A GB 1565351A
Authority
GB
United Kingdom
Prior art keywords
group
methyl
hydrogen atom
compound
tetrahydropyran
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2518775A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Theramex SAM
Original Assignee
Laboratoire Theramex SAM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Theramex SAM filed Critical Laboratoire Theramex SAM
Priority to GB2518775A priority Critical patent/GB1565351A/en
Priority to FR7617320A priority patent/FR2361899A1/fr
Publication of GB1565351A publication Critical patent/GB1565351A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB2518775A 1975-06-02 1975-06-02 Steroid aminoethers Expired GB1565351A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB2518775A GB1565351A (en) 1975-06-02 1975-06-02 Steroid aminoethers
FR7617320A FR2361899A1 (fr) 1975-06-02 1976-06-09 Nouveaux aminoethers de steroides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2518775A GB1565351A (en) 1975-06-02 1975-06-02 Steroid aminoethers

Publications (1)

Publication Number Publication Date
GB1565351A true GB1565351A (en) 1980-04-16

Family

ID=10223653

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2518775A Expired GB1565351A (en) 1975-06-02 1975-06-02 Steroid aminoethers

Country Status (2)

Country Link
FR (1) FR2361899A1 (https=)
GB (1) GB1565351A (https=)

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5637691A (en) * 1993-03-10 1997-06-10 Magainin Pharmaceuticals, Inc. Steroid derivatives, pharmaceutical compositions containing them, and their use as antibiotics or disinfectants
US5763430A (en) * 1995-06-07 1998-06-09 Magainin Pharmaceuticals Inc. Method of treating a viral infection by administering a steroid compound
US5792635A (en) * 1995-06-07 1998-08-11 Magainin Pharmaceuticals, Inc. Method of inhibiting the sodium/proton exchanger NHE3 and method of inhibiting growth by administering squalamine
US5795885A (en) * 1995-06-07 1998-08-18 Magainin Pharmaceuticals Inc. Method of inhibiting profileration of cells by administering an aminosterol compound
US5840740A (en) * 1995-06-07 1998-11-24 Magainin Pharmaceuticals Inc. Aminosterol compounds and a method of treating infection using the aminosterol compounds
US5840936A (en) * 1995-06-07 1998-11-24 Magainin Pharmaceuticals Inc. Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE)
US5847172A (en) * 1995-06-07 1998-12-08 Magainin Pharmaceuticals Inc. Certain aminosterol compounds and pharmaceutical compositions including these compounds
US5856535A (en) * 1994-08-18 1999-01-05 Magainin Pharmaceuticals, Inc. Aminosterol ester compounds
US5874597A (en) * 1995-06-07 1999-02-23 Magainin Pharmaceuticals, Inc. Certain aminosterol compounds and pharmaceutical compositions including these compounds
US5994336A (en) * 1995-06-07 1999-11-30 Magainin Pharmaceuticals Inc. Method of inhibiting proliferation of cells by administering an aminosterol compound
US6143738A (en) * 1995-06-07 2000-11-07 Magainin Pharmaceuticals, Inc. Therapeutic uses for an aminosterol compound
US6147060A (en) * 1996-04-26 2000-11-14 Magainin Pharmaceuticals Treatment of carcinomas using squalamine in combination with other anti-cancer agents
US6262283B1 (en) 1996-12-06 2001-07-17 Magainin Pharmaceuticals Inc. Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds
US6596712B2 (en) 1996-04-26 2003-07-22 Genaera Corporation Treatment of carcinomas using squalamine in combination with other anti-cancer agents or modalities
US6933383B2 (en) 2000-04-12 2005-08-23 Genaera Corporation Regioselective and stereoselective oxidation of fused ring systems useful for the preparation of aminosterols
US8987236B2 (en) 2000-07-13 2015-03-24 Ohr Pharmaceutical, Inc. Therapeutic uses for an aminosterol compound

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2272883A (en) * 1982-12-22 1984-06-28 Herpes Pharmaceutical Inc. Pharmaceutical compositions of steriods for treatment of herpes simplex infections
ES2164110T3 (es) * 1994-03-10 2002-02-16 Magainin Pharma Usos farmaceuticos de derivados de esteroides.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3206457A (en) * 1960-11-16 1965-09-14 Searle & Co 3-aminoalkyl ethers of 17-oxygenated androst-5-en-3-ols and 20-oxygenated pregn-5-en-3-ols, and 5alpha, 6-dihydro compounds corresponding
US3210386A (en) * 1961-01-09 1965-10-05 Upjohn Co 3-aminoethers of 3beta-hydroxy androstanes
US3169132A (en) * 1961-04-07 1965-02-09 Upjohn Co 3-aminoether pregnanes
US3000910A (en) * 1961-04-07 1961-09-19 Upjohn Co 17-isonitrose-3-aminoethers of the androstane series
GB1205341A (en) * 1968-04-19 1970-09-16 Jean Marie Gastaud Pregnane derivative and preparation thereof

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5721226A (en) * 1993-03-10 1998-02-24 Magainin Pharmaceuticals Inc. Method for inhibiting angiogenesis using squalamine and squalamine steroid derivatives
US5733899A (en) * 1993-03-10 1998-03-31 Magainin Pharmaceuticals Inc. Method for treating infection using steroid based pharmaceutical compositions
US5637691A (en) * 1993-03-10 1997-06-10 Magainin Pharmaceuticals, Inc. Steroid derivatives, pharmaceutical compositions containing them, and their use as antibiotics or disinfectants
US5856535A (en) * 1994-08-18 1999-01-05 Magainin Pharmaceuticals, Inc. Aminosterol ester compounds
US5874597A (en) * 1995-06-07 1999-02-23 Magainin Pharmaceuticals, Inc. Certain aminosterol compounds and pharmaceutical compositions including these compounds
US5994336A (en) * 1995-06-07 1999-11-30 Magainin Pharmaceuticals Inc. Method of inhibiting proliferation of cells by administering an aminosterol compound
US5840740A (en) * 1995-06-07 1998-11-24 Magainin Pharmaceuticals Inc. Aminosterol compounds and a method of treating infection using the aminosterol compounds
US5840936A (en) * 1995-06-07 1998-11-24 Magainin Pharmaceuticals Inc. Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE)
US5847172A (en) * 1995-06-07 1998-12-08 Magainin Pharmaceuticals Inc. Certain aminosterol compounds and pharmaceutical compositions including these compounds
US5792635A (en) * 1995-06-07 1998-08-11 Magainin Pharmaceuticals, Inc. Method of inhibiting the sodium/proton exchanger NHE3 and method of inhibiting growth by administering squalamine
US5763430A (en) * 1995-06-07 1998-06-09 Magainin Pharmaceuticals Inc. Method of treating a viral infection by administering a steroid compound
US5795885A (en) * 1995-06-07 1998-08-18 Magainin Pharmaceuticals Inc. Method of inhibiting profileration of cells by administering an aminosterol compound
US6143738A (en) * 1995-06-07 2000-11-07 Magainin Pharmaceuticals, Inc. Therapeutic uses for an aminosterol compound
US6147060A (en) * 1996-04-26 2000-11-14 Magainin Pharmaceuticals Treatment of carcinomas using squalamine in combination with other anti-cancer agents
US6596712B2 (en) 1996-04-26 2003-07-22 Genaera Corporation Treatment of carcinomas using squalamine in combination with other anti-cancer agents or modalities
US6262283B1 (en) 1996-12-06 2001-07-17 Magainin Pharmaceuticals Inc. Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds
US6610866B2 (en) 1996-12-06 2003-08-26 Magainin Pharmaceuticals, Inc. Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds
US6933383B2 (en) 2000-04-12 2005-08-23 Genaera Corporation Regioselective and stereoselective oxidation of fused ring systems useful for the preparation of aminosterols
US7728157B2 (en) 2000-04-12 2010-06-01 Ohr Pharmaceutical Inc. Regioselective and stereoselective oxidation of fused ring systems useful for the preparation of aminosterols
US8987236B2 (en) 2000-07-13 2015-03-24 Ohr Pharmaceutical, Inc. Therapeutic uses for an aminosterol compound

Also Published As

Publication number Publication date
FR2361899B1 (https=) 1978-12-08
FR2361899A1 (fr) 1978-03-17

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee