GB1564527A - Phenylpiperazinotetrahydronaphthols and derivates - Google Patents

Phenylpiperazinotetrahydronaphthols and derivates Download PDF

Info

Publication number
GB1564527A
GB1564527A GB37036/76A GB3703676A GB1564527A GB 1564527 A GB1564527 A GB 1564527A GB 37036/76 A GB37036/76 A GB 37036/76A GB 3703676 A GB3703676 A GB 3703676A GB 1564527 A GB1564527 A GB 1564527A
Authority
GB
United Kingdom
Prior art keywords
trans
tetrahydro
methoxyphenyl
compound
piperazinyll
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB37036/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of GB1564527A publication Critical patent/GB1564527A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB37036/76A 1975-09-15 1976-09-07 Phenylpiperazinotetrahydronaphthols and derivates Expired GB1564527A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/613,721 US4018773A (en) 1975-09-15 1975-09-15 Phenylpiperazinotetrahydronaphthols and derivatives

Publications (1)

Publication Number Publication Date
GB1564527A true GB1564527A (en) 1980-04-10

Family

ID=24458453

Family Applications (1)

Application Number Title Priority Date Filing Date
GB37036/76A Expired GB1564527A (en) 1975-09-15 1976-09-07 Phenylpiperazinotetrahydronaphthols and derivates

Country Status (5)

Country Link
US (2) US4018773A (enExample)
JP (1) JPS5236674A (enExample)
DE (1) DE2641499A1 (enExample)
FR (1) FR2323388A1 (enExample)
GB (1) GB1564527A (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4018773A (en) * 1975-09-15 1977-04-19 E. R. Squibb & Sons, Inc. Phenylpiperazinotetrahydronaphthols and derivatives
FI68821C (fi) * 1977-07-18 1985-11-11 Sandoz Ag Analogifoerfarande foer framstaellning av nya tetralinderivat vilka saenker blodtryck och oekar blodetsgenomstroemning
GB8615560D0 (en) * 1986-06-25 1986-07-30 Maggioni Farma Aminoalcohols
JPH01503777A (ja) * 1985-10-04 1989-12-21 マツジヨ‐ニ‐ウインスロツプ・ソチエタ・ペル・アチオニ 縮合脂環式アミノアルコール類
US5153225A (en) * 1986-12-10 1992-10-06 Bayer Aktiengesellschaft Substituted basic 2-aminotetralin in pharmaceuticals
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline
US4845221A (en) * 1988-04-15 1989-07-04 American Home Products Corporation Serotonergic substituted piperazinyl tetralins
EP1205473A4 (en) * 1999-07-28 2004-06-16 Daiichi Radioisotope Lab VESAMICOL PIPERAZINE DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING THESE DERIVATIVES
JP6496101B2 (ja) * 2013-04-05 2019-04-03 浜松ホトニクス株式会社 アセチルコリン小胞トランスポーターの検出に適した化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3845058A (en) * 1970-07-20 1974-10-29 R Viterbo N-(3,4-dihydro naphthyl)-n'phenyl piperazines
DE2325633A1 (de) * 1973-05-21 1974-12-12 Boehringer Sohn Ingelheim Piperazinderivate
US4018773A (en) * 1975-09-15 1977-04-19 E. R. Squibb & Sons, Inc. Phenylpiperazinotetrahydronaphthols and derivatives

Also Published As

Publication number Publication date
US4018773A (en) 1977-04-19
FR2323388B1 (enExample) 1978-11-03
DE2641499A1 (de) 1977-03-31
US4081444A (en) 1978-03-28
FR2323388A1 (fr) 1977-04-08
JPS5236674A (en) 1977-03-22

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee