GB1552497A - 1314 - didehydro 16-fluoroprostaglandis - Google Patents

1314 - didehydro 16-fluoroprostaglandis

Info

Publication number
GB1552497A
GB1552497A GB36570/76A GB3657076A GB1552497A GB 1552497 A GB1552497 A GB 1552497A GB 36570/76 A GB36570/76 A GB 36570/76A GB 3657076 A GB3657076 A GB 3657076A GB 1552497 A GB1552497 A GB 1552497A
Authority
GB
United Kingdom
Prior art keywords
fluoroprostaglandis
didehydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB36570/76A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Chicago
Original Assignee
University of Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Chicago filed Critical University of Chicago
Publication of GB1552497A publication Critical patent/GB1552497A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/42Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing triple carbon-to-carbon bonds, e.g. with metal-alkynes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB36570/76A 1975-09-10 1976-09-03 1314 - didehydro 16-fluoroprostaglandis Expired GB1552497A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61185575A 1975-09-10 1975-09-10

Publications (1)

Publication Number Publication Date
GB1552497A true GB1552497A (en) 1979-09-12

Family

ID=24450658

Family Applications (4)

Application Number Title Priority Date Filing Date
GB36570/76A Expired GB1552497A (en) 1975-09-10 1976-09-03 1314 - didehydro 16-fluoroprostaglandis
GB289/78A Expired GB1552498A (en) 1975-09-10 1976-09-03 Intermediates in the preparation of 13,14-didehydro - 16 fluoroprostaglandins
GB291/78A Expired GB1552500A (en) 1975-09-10 1976-09-03 Aluminium acetylides
GB290/78A Expired GB1552499A (en) 1975-09-10 1976-09-03 Intermediates in the preparation of 1314-didehydro - 16 -fluoroprostaglandins

Family Applications After (3)

Application Number Title Priority Date Filing Date
GB289/78A Expired GB1552498A (en) 1975-09-10 1976-09-03 Intermediates in the preparation of 13,14-didehydro - 16 fluoroprostaglandins
GB291/78A Expired GB1552500A (en) 1975-09-10 1976-09-03 Aluminium acetylides
GB290/78A Expired GB1552499A (en) 1975-09-10 1976-09-03 Intermediates in the preparation of 1314-didehydro - 16 -fluoroprostaglandins

Country Status (8)

Country Link
JP (1) JPS5248643A (en)
AU (1) AU1722176A (en)
BE (1) BE846080A (en)
DE (1) DE2640487A1 (en)
ES (1) ES451093A1 (en)
FR (1) FR2323379A1 (en)
GB (4) GB1552497A (en)
ZA (1) ZA765031B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA77160B (en) * 1976-02-13 1977-11-30 Upjohn Co Prostaglandin analogs
IL51877A (en) * 1976-06-01 1981-09-13 Carlo Erba Sa -nor-16-benzyl or phenoxy-13,14-dehydro-prostaglandins and process for their preparation

Also Published As

Publication number Publication date
ZA765031B (en) 1977-10-26
AU1722176A (en) 1978-03-02
GB1552498A (en) 1979-09-12
GB1552500A (en) 1979-09-12
BE846080A (en) 1977-03-10
GB1552499A (en) 1979-09-12
JPS5248643A (en) 1977-04-18
DE2640487A1 (en) 1977-04-14
FR2323379A1 (en) 1977-04-08
ES451093A1 (en) 1977-09-01

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee