GB1548334A - Carbamate derivatives - Google Patents

Carbamate derivatives

Info

Publication number
GB1548334A
GB1548334A GB257777A GB257777A GB1548334A GB 1548334 A GB1548334 A GB 1548334A GB 257777 A GB257777 A GB 257777A GB 257777 A GB257777 A GB 257777A GB 1548334 A GB1548334 A GB 1548334A
Authority
GB
United Kingdom
Prior art keywords
carbamate derivatives
dihydroxymethylpyridine
methylcarbamate
recrystallisation
hydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB257777A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of GB1548334A publication Critical patent/GB1548334A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

2,6-Dihydroxymethylpyridine-bis-(N-methylcarbamate) in the gamma 2 modification is obtained from 2,6-dihydroxymethylpyridine hydrochloride using methyl isocyanate, the purification being effected by recrystallisation from an alcohol-water mixture and the drying being carried out at 50-100 DEG C. The product thus obtained, which is employed in the therapy of vascular diseases, can easily be made into tablets.
GB257777A 1976-01-24 1977-01-21 Carbamate derivatives Expired GB1548334A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU76RI584A HU171664B (en) 1976-01-24 1976-01-24 Process for preparing 2,6-dihydroxymethyl-pyridine-bis/n-methyl-carbamate / in gamma 2 crystal form for direct tablet compression

Publications (1)

Publication Number Publication Date
GB1548334A true GB1548334A (en) 1979-07-11

Family

ID=11000992

Family Applications (1)

Application Number Title Priority Date Filing Date
GB257777A Expired GB1548334A (en) 1976-01-24 1977-01-21 Carbamate derivatives

Country Status (10)

Country Link
JP (1) JPS5291870A (en)
AT (1) AT347968B (en)
CH (1) CH638496A5 (en)
CS (1) CS215094B2 (en)
DD (1) DD129213A5 (en)
DE (1) DE2702772A1 (en)
GB (1) GB1548334A (en)
HU (1) HU171664B (en)
PL (1) PL106095B1 (en)
SU (2) SU689619A3 (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL126013C (en) * 1963-04-13 1900-01-01
AT258954B (en) * 1963-04-13 1967-12-27 Michiro Inoue Process for the preparation of new bis (hydroxymethyl) pyridinedicarbamate derivatives
AT258953B (en) * 1963-04-13 1967-12-27 Michiro Inoue Process for the preparation of new bis (hydroxymethyl) pyridinedicarbamate derivatives
AT258955B (en) * 1965-11-08 1967-12-27 Michiro Inoue Process for the preparation of new bis (hydroxymethyl) pyridinedicarbamate derivatives
ES377775A1 (en) * 1970-03-21 1973-06-01 Prodes Sa Procedure for the obtaining of ester bis- (N-meticarbamico) of 2,6-piridindimetanol. (Machine-translation by Google Translate, not legally binding)
JPS497286A (en) * 1972-05-24 1974-01-22

Also Published As

Publication number Publication date
CS215094B2 (en) 1982-07-30
CH638496A5 (en) 1983-09-30
HU171664B (en) 1978-02-28
SU689619A3 (en) 1979-09-30
DE2702772A1 (en) 1977-07-28
DE2702772C2 (en) 1988-01-21
JPS6135984B2 (en) 1986-08-15
PL106095B1 (en) 1979-11-30
ATA22277A (en) 1978-06-15
JPS5291870A (en) 1977-08-02
AT347968B (en) 1979-01-25
SU697051A3 (en) 1979-11-05
DD129213A5 (en) 1978-01-04

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19940121