GB1539102A - Pharmaceutical compositions including low molecular weight polypeptides - Google Patents

Pharmaceutical compositions including low molecular weight polypeptides

Info

Publication number
GB1539102A
GB1539102A GB12632/76A GB1263276A GB1539102A GB 1539102 A GB1539102 A GB 1539102A GB 12632/76 A GB12632/76 A GB 12632/76A GB 1263276 A GB1263276 A GB 1263276A GB 1539102 A GB1539102 A GB 1539102A
Authority
GB
United Kingdom
Prior art keywords
amino acid
molecular weight
pharmaceutical compositions
low molecular
compositions including
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB12632/76A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19762602443 external-priority patent/DE2602443A1/en
Application filed by University of California filed Critical University of California
Publication of GB1539102A publication Critical patent/GB1539102A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The novel polypeptides consist of a sequence of 3 to 10 amino acids which corresponds to a part of the amino acid sequence 265 - 537 of the Fc region of immunoglobulin E (IgE). A first amino acid or a peptide, which may be covalently bonded to a solid carrier, is condensed with a second amino acid or a peptide so that the total number of the amino acid radicals is equal to that of the polypeptide to be prepared. Carboxyl and amino groups, except for those which are to react, are present in protected form; the protecting groups and the solid carrier are subsequently cleaved off. The polypeptides are also converted into salts, esters, amides, N-acyl derivatives and O-acyl derivatives. The compounds block the bonding sites of IgE; they can be used for the prophylaxis or treatment of the symptoms of allergic reactions.
GB12632/76A 1975-04-04 1976-03-29 Pharmaceutical compositions including low molecular weight polypeptides Expired GB1539102A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56542575A 1975-04-04 1975-04-04
DE19762602443 DE2602443A1 (en) 1975-04-04 1976-01-23 BIOLOGICALLY ACTIVE POLYPEPTIDES

Publications (1)

Publication Number Publication Date
GB1539102A true GB1539102A (en) 1979-01-24

Family

ID=25769954

Family Applications (1)

Application Number Title Priority Date Filing Date
GB12632/76A Expired GB1539102A (en) 1975-04-04 1976-03-29 Pharmaceutical compositions including low molecular weight polypeptides

Country Status (8)

Country Link
AU (1) AU514308B2 (en)
CA (1) CA1087171A (en)
CH (1) CH624093A5 (en)
FR (1) FR2305989A1 (en)
GB (1) GB1539102A (en)
MX (1) MX3790E (en)
NL (1) NL7603384A (en)
SE (1) SE430058B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2162133A1 (en) * 2007-07-09 2010-03-17 Nestec S.A. Methods for reducing allergies caused by environmental allergens
US9388236B2 (en) 2007-07-09 2016-07-12 Nestec Sa Methods for reducing allergies caused by environmental allergens
EP3720415A4 (en) * 2017-12-06 2021-11-24 Steven W. Bailey Peptide compositions for slowing degradation of vitamin-mineral supplements, foods, pharmaceuticals, and cosmetics

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2162133A1 (en) * 2007-07-09 2010-03-17 Nestec S.A. Methods for reducing allergies caused by environmental allergens
EP2162133A4 (en) * 2007-07-09 2011-06-15 Nestec Sa Methods for reducing allergies caused by environmental allergens
EP2705846A3 (en) * 2007-07-09 2014-05-28 Nestec S.A. Methods for reducing allergies caused by environmental allergens
US9388236B2 (en) 2007-07-09 2016-07-12 Nestec Sa Methods for reducing allergies caused by environmental allergens
EP3720415A4 (en) * 2017-12-06 2021-11-24 Steven W. Bailey Peptide compositions for slowing degradation of vitamin-mineral supplements, foods, pharmaceuticals, and cosmetics
US11912785B2 (en) 2017-12-06 2024-02-27 Steven W. Bailey Peptide compositions for slowing degradation of vitamin mineral supplements, foods, pharmaceutical and cosmetics

Also Published As

Publication number Publication date
AU1230376A (en) 1977-09-29
MX3790E (en) 1981-07-20
AU514308B2 (en) 1981-02-05
FR2305989B1 (en) 1979-10-05
FR2305989A1 (en) 1976-10-29
SE7603897L (en) 1976-10-05
CA1087171A (en) 1980-10-07
NL7603384A (en) 1976-10-06
SE430058B (en) 1983-10-17
CH624093A5 (en) 1981-07-15

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Legal Events

Date Code Title Description
PS Patent sealed
PE20 Patent expired after termination of 20 years

Effective date: 19960328