GB1528071A - Radioimmunoassay - Google Patents
RadioimmunoassayInfo
- Publication number
- GB1528071A GB1528071A GB7548/76A GB754876A GB1528071A GB 1528071 A GB1528071 A GB 1528071A GB 7548/76 A GB7548/76 A GB 7548/76A GB 754876 A GB754876 A GB 754876A GB 1528071 A GB1528071 A GB 1528071A
- Authority
- GB
- United Kingdom
- Prior art keywords
- ria
- reagent
- antigens
- antibodies
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000003127 radioimmunoassay Methods 0.000 title abstract 6
- 239000000427 antigen Substances 0.000 abstract 6
- 102000036639 antigens Human genes 0.000 abstract 6
- 108091007433 antigens Proteins 0.000 abstract 6
- 239000003153 chemical reaction reagent Substances 0.000 abstract 4
- 239000007790 solid phase Substances 0.000 abstract 2
- XUIIKFGFIJCVMT-GFCCVEGCSA-N D-thyroxine Chemical compound IC1=CC(C[C@@H](N)C(O)=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-GFCCVEGCSA-N 0.000 abstract 1
- WDJUZGPOPHTGOT-OAXVISGBSA-N Digitoxin Natural products O([C@H]1[C@@H](C)O[C@@H](O[C@@H]2C[C@@H]3[C@@](C)([C@@H]4[C@H]([C@]5(O)[C@@](C)([C@H](C6=CC(=O)OC6)CC5)CC4)CC3)CC2)C[C@H]1O)[C@H]1O[C@@H](C)[C@H](O[C@H]2O[C@@H](C)[C@@H](O)[C@@H](O)C2)[C@@H](O)C1 WDJUZGPOPHTGOT-OAXVISGBSA-N 0.000 abstract 1
- LTMHDMANZUZIPE-AMTYYWEZSA-N Digoxin Natural products O([C@H]1[C@H](C)O[C@H](O[C@@H]2C[C@@H]3[C@@](C)([C@@H]4[C@H]([C@]5(O)[C@](C)([C@H](O)C4)[C@H](C4=CC(=O)OC4)CC5)CC3)CC2)C[C@@H]1O)[C@H]1O[C@H](C)[C@@H](O[C@H]2O[C@@H](C)[C@H](O)[C@@H](O)C2)[C@@H](O)C1 LTMHDMANZUZIPE-AMTYYWEZSA-N 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- AUYYCJSJGJYCDS-LBPRGKRZSA-N Thyrolar Chemical compound IC1=CC(C[C@H](N)C(O)=O)=CC(I)=C1OC1=CC=C(O)C(I)=C1 AUYYCJSJGJYCDS-LBPRGKRZSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 229960000648 digitoxin Drugs 0.000 abstract 1
- WDJUZGPOPHTGOT-XUDUSOBPSA-N digitoxin Chemical compound C1[C@H](O)[C@H](O)[C@@H](C)O[C@H]1O[C@@H]1[C@@H](C)O[C@@H](O[C@@H]2[C@H](O[C@@H](O[C@@H]3C[C@@H]4[C@]([C@@H]5[C@H]([C@]6(CC[C@@H]([C@@]6(C)CC5)C=5COC(=O)C=5)O)CC4)(C)CC3)C[C@@H]2O)C)C[C@@H]1O WDJUZGPOPHTGOT-XUDUSOBPSA-N 0.000 abstract 1
- 229960005156 digoxin Drugs 0.000 abstract 1
- LTMHDMANZUZIPE-PUGKRICDSA-N digoxin Chemical compound C1[C@H](O)[C@H](O)[C@@H](C)O[C@H]1O[C@@H]1[C@@H](C)O[C@@H](O[C@@H]2[C@H](O[C@@H](O[C@@H]3C[C@@H]4[C@]([C@@H]5[C@H]([C@]6(CC[C@@H]([C@@]6(C)[C@H](O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)C[C@@H]2O)C)C[C@@H]1O LTMHDMANZUZIPE-PUGKRICDSA-N 0.000 abstract 1
- LTMHDMANZUZIPE-UHFFFAOYSA-N digoxine Natural products C1C(O)C(O)C(C)OC1OC1C(C)OC(OC2C(OC(OC3CC4C(C5C(C6(CCC(C6(C)C(O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)CC2O)C)CC1O LTMHDMANZUZIPE-UHFFFAOYSA-N 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 108010074605 gamma-Globulins Proteins 0.000 abstract 1
- 239000007791 liquid phase Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 229940034208 thyroxine Drugs 0.000 abstract 1
- XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 abstract 1
- 229940035722 triiodothyronine Drugs 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/534—Production of labelled immunochemicals with radioactive label
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/817—Steroids or hormones
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/826—Additives, e.g. buffers, diluents, preservatives
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/555,215 US3995019A (en) | 1975-03-04 | 1975-03-04 | Diagnostic reagent system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1528071A true GB1528071A (en) | 1978-10-11 |
Family
ID=24216433
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7548/76A Expired GB1528071A (en) | 1975-03-04 | 1976-02-26 | Radioimmunoassay |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3995019A (enExample) |
| JP (1) | JPS51112516A (enExample) |
| AU (1) | AU499184B2 (enExample) |
| BE (1) | BE839142A (enExample) |
| DE (1) | DE2608667A1 (enExample) |
| DK (1) | DK92076A (enExample) |
| ES (1) | ES445768A1 (enExample) |
| FR (1) | FR2303292A1 (enExample) |
| GB (1) | GB1528071A (enExample) |
| IT (1) | IT1056844B (enExample) |
| NL (1) | NL7602152A (enExample) |
| SE (1) | SE7602834L (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4069352A (en) * | 1976-07-02 | 1978-01-17 | Baxter Travenol Laboratories, Inc. | Immunoadsorbent polymeric material and method of making same |
| US4098876A (en) * | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
| US4182750A (en) * | 1977-04-21 | 1980-01-08 | Sullivan Thomas E | Bloodcompatible functional polymers |
| US4307071A (en) * | 1977-08-02 | 1981-12-22 | Kallestad Laboratories, Inc. | Analytical reagent and method |
| NL7713952A (nl) * | 1977-12-16 | 1979-06-19 | Philips Nv | Radio-immunologische methode voor het bepalen van de schildklierfunktie door een in vitro onderzoek in bloedserum. |
| US4244940A (en) * | 1978-09-05 | 1981-01-13 | Bio-Rad Laboratories, Inc. | Single-incubation two-site immunoassay |
| US4241175A (en) * | 1978-12-18 | 1980-12-23 | Merck & Co., Inc. | Assay for hepatitis B core antibody |
| US4273867A (en) * | 1979-04-05 | 1981-06-16 | Mallinckrodt, Inc. | Method and reagent for counteracting lipemic interference |
| US4298592A (en) * | 1979-04-05 | 1981-11-03 | Mallinckrodt, Inc. | Double antibody separation method |
| DE3026665A1 (de) * | 1980-07-14 | 1982-02-11 | Hoechst Ag, 6000 Frankfurt | Verfahren zum binden und trennen fuer den kompetitiven radioimmunoassay und reagenz hierzu |
| GB8307156D0 (en) * | 1983-03-15 | 1983-04-20 | Celltech Ltd | Heterogeneous binding assays |
| US4935339A (en) * | 1985-05-07 | 1990-06-19 | Nichols Institute Diagnostics | Delayed solid phase immunologic assay |
| US4855242A (en) * | 1986-04-14 | 1989-08-08 | Joslin Diabetes Center, Inc. | Method of detecting antibodies |
| US4764475A (en) * | 1986-12-01 | 1988-08-16 | The University Of British Columbia | Pancreas dependant immunoassay for determining subpopulations of monoclonal antibodies to somatostatin. |
| US5306623A (en) * | 1989-08-28 | 1994-04-26 | Lifescan, Inc. | Visual blood glucose concentration test strip |
| US6395227B1 (en) * | 1989-08-28 | 2002-05-28 | Lifescan, Inc. | Test strip for measuring analyte concentration over a broad range of sample volume |
| AU640162B2 (en) * | 1989-08-28 | 1993-08-19 | Lifescan, Inc. | Blood separation and analyte detection techniques |
| US6730023B1 (en) * | 1999-10-15 | 2004-05-04 | Hemopet | Animal genetic and health profile database management |
| US7548839B2 (en) * | 1999-10-15 | 2009-06-16 | Hemopet | System for animal health diagnosis |
| US8234099B2 (en) * | 1999-10-15 | 2012-07-31 | Hemopet | Computer program for determining a nutritional diet product for a canine or feline animal |
| WO2006138451A2 (en) * | 2005-06-15 | 2006-12-28 | Panterra Engineered Plastics, Inc. | Method of creating high strength expanded thermoformable honeycomb structures with cementitious reinforcement |
| US8012769B2 (en) * | 2008-11-12 | 2011-09-06 | Hemopet | Thyroid analyte detection and measurement |
| US7799532B2 (en) * | 2008-11-12 | 2010-09-21 | Hemopet | Detection and measurement of thyroid hormone autoantibodies |
| US7794954B2 (en) * | 2008-11-12 | 2010-09-14 | Hemopet | Detection and measurement of thyroid analyte profile |
| US7873482B2 (en) * | 2008-12-16 | 2011-01-18 | Bruno Stefanon | Diagnostic system for selecting nutrition and pharmacological products for animals |
| US20100151062A1 (en) * | 2008-12-16 | 2010-06-17 | Bruno Stefanon | Determining nutrients for animals through gene expression |
| CN108982836A (zh) * | 2018-05-31 | 2018-12-11 | 湖南远璟生物技术有限公司 | 一种总甲状腺素磁微粒化学发光免疫定量检测试剂盒及其制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL286954A (enExample) * | 1962-01-03 | |||
| US3655838A (en) * | 1969-03-20 | 1972-04-11 | Organon | Method of pelletizing analytical or immunological reagents |
-
1975
- 1975-03-04 US US05/555,215 patent/US3995019A/en not_active Expired - Lifetime
-
1976
- 1976-02-26 GB GB7548/76A patent/GB1528071A/en not_active Expired
- 1976-02-27 SE SE7602834A patent/SE7602834L/xx not_active Application Discontinuation
- 1976-03-02 JP JP51023020A patent/JPS51112516A/ja active Pending
- 1976-03-02 NL NL7602152A patent/NL7602152A/xx not_active Application Discontinuation
- 1976-03-03 FR FR7605978A patent/FR2303292A1/fr active Granted
- 1976-03-03 IT IT20817/76A patent/IT1056844B/it active
- 1976-03-03 AU AU11614/76A patent/AU499184B2/en not_active Expired
- 1976-03-03 DK DK92076*#A patent/DK92076A/da unknown
- 1976-03-03 DE DE19762608667 patent/DE2608667A1/de not_active Withdrawn
- 1976-03-03 BE BE164815A patent/BE839142A/xx unknown
- 1976-03-04 ES ES445768A patent/ES445768A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU1161476A (en) | 1977-09-08 |
| BE839142A (fr) | 1976-07-01 |
| ES445768A1 (es) | 1977-10-16 |
| SE7602834L (sv) | 1976-09-05 |
| NL7602152A (nl) | 1976-09-07 |
| FR2303292A1 (fr) | 1976-10-01 |
| DE2608667A1 (de) | 1976-09-09 |
| FR2303292B3 (enExample) | 1978-12-01 |
| JPS51112516A (en) | 1976-10-05 |
| DK92076A (da) | 1976-09-05 |
| IT1056844B (it) | 1982-02-20 |
| US3995019A (en) | 1976-11-30 |
| AU499184B2 (en) | 1979-04-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1528071A (en) | Radioimmunoassay | |
| US5026653A (en) | Scavenger antibody mixture and its use for immunometric assay | |
| Midgley Jr et al. | Radioimmunoassays employing double antibody techniques | |
| CA1105381A (en) | Competitive immunoassay for hapten using enzyme labelled antibody | |
| Vaidya et al. | Eliminating interference from heterophilic antibodies in a two-site immunoassay for creatine kinase MB by using F (ab') 2 conjugate and polyclonal mouse IgG | |
| GB1327545A (en) | Barbituric acid antigens antibodies therefor and a method of assay of barbituric acid derivatives | |
| NZ191317A (en) | Immunological determination of immuno-complexes diagnostic agent | |
| US4427781A (en) | Particle agglutination immunoassay with agglutinator for determining haptens; PACIA | |
| US4690908A (en) | Measuring reagent kit for determining an antigen, antibody or antigen-antibody complex | |
| IE44204L (en) | Reagent for pregnancy testing | |
| ES8304314A1 (es) | "metodo y su correspondiente aparato para el ensayo de anticuerpos con respecto a antigenos solubles". | |
| FR2708348B1 (fr) | Procédé de dosage d'une substance immunologique au moyen de particules de latex magnétiques et de particules non-magnétiques. | |
| GB1508104A (en) | Method for quantitative determination of an antigenic substance and a diagnostic kit therefor | |
| JPH0616044B2 (ja) | 免疫学的ラテツクス凝集法 | |
| Couroucé-Pauty et al. | Simultaneous occurrence in the same serum of hepatitis B surface antigen and antibody to hepatitis B surface antigen of different subtypes | |
| CA1088422A (en) | Double anti body-coated solid phase | |
| US4172117A (en) | Method for the simultaneous measurement of antigens and their antibodies by solid-phase radioimmunoassay | |
| Kline et al. | Hepatitis B core antibody (anti‐HBc) in blood donors in the United States: implications for surrogate testing programs | |
| Lachmann | A sedimentation pattern technique for measuring conglutination: its application to demonstrating immunoconglutinins to C′ 4 | |
| Rush et al. | Solid-phase radioimmunoassay on polystyrene beads and its application to dopamine-β-hydroxylase | |
| Metzgar et al. | Detection of tissue isoantigens on primary and serial heteroploid cell lines of human origin by the mixed agglutination technique | |
| GB1522566A (en) | Assay for free thyroid hormones | |
| ES8305500A1 (es) | Un procedimiento para la determinacion cuantitativa y cualitativa de antigenos, anticuerpos y complejos de los mismos. | |
| JP3220546B2 (ja) | 免疫複合体存在下の抗原または抗体の測定方法 | |
| Kida et al. | A radioimmunoassay employing polyethylene glycol (PEG) for measuring dilute concentrations of rat hemopexin, albumin and haptoglobin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |