GB1523631A - Sulphonamide derivatives - Google Patents

Sulphonamide derivatives

Info

Publication number
GB1523631A
GB1523631A GB28770/75A GB2877075A GB1523631A GB 1523631 A GB1523631 A GB 1523631A GB 28770/75 A GB28770/75 A GB 28770/75A GB 2877075 A GB2877075 A GB 2877075A GB 1523631 A GB1523631 A GB 1523631A
Authority
GB
United Kingdom
Prior art keywords
sulphonamide derivatives
sulphonamide
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB28770/75A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leo Pharma AS
Original Assignee
Leo Pharmaceutical Products Ltd AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharmaceutical Products Ltd AS filed Critical Leo Pharmaceutical Products Ltd AS
Priority to GB28770/75A priority Critical patent/GB1523631A/en
Priority to IE1285/76A priority patent/IE43009B1/en
Priority to NZ181168A priority patent/NZ181168A/xx
Priority to US05/696,547 priority patent/US4082851A/en
Priority to ZA763580A priority patent/ZA763580B/xx
Priority to GR51105A priority patent/GR60429B/el
Priority to AT473076A priority patent/AT345783B/de
Priority to PT65317A priority patent/PT65317B/pt
Priority to SU762377347A priority patent/SU644374A3/ru
Priority to DK302776A priority patent/DK302776A/da
Priority to CA256,326A priority patent/CA1077953A/en
Priority to JP7956776A priority patent/JPS5212147A/ja
Priority to BE168670A priority patent/BE843828A/xx
Priority to SE7607786A priority patent/SE7607786L/xx
Priority to ES449648A priority patent/ES449648A1/es
Priority to FI761987A priority patent/FI761987A7/fi
Priority to LU75322A priority patent/LU75322A1/xx
Priority to IT7668697A priority patent/IT1063145B/it
Priority to NL7607505A priority patent/NL7607505A/xx
Priority to DE2630637A priority patent/DE2630637C2/de
Priority to FR7620790A priority patent/FR2316929A1/fr
Priority to AU15677/76A priority patent/AU503344B2/en
Priority to US05/862,976 priority patent/US4247550A/en
Publication of GB1523631A publication Critical patent/GB1523631A/en
Priority to IE2496/78A priority patent/IE43010B1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/14—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB28770/75A 1975-07-08 1975-07-08 Sulphonamide derivatives Expired GB1523631A (en)

Priority Applications (24)

Application Number Priority Date Filing Date Title
GB28770/75A GB1523631A (en) 1975-07-08 1975-07-08 Sulphonamide derivatives
IE1285/76A IE43009B1 (en) 1975-07-08 1976-06-14 Sulfonamide derivatives
NZ181168A NZ181168A (en) 1975-07-08 1976-06-15 3-sulphamyl benzylamine derivatives and pharmaceutical compositions intermidiates
US05/696,547 US4082851A (en) 1975-07-08 1976-06-16 Sulphonamides, compositions containing the same and methods for using the same in the treatment of hypertension or odemeas
ZA763580A ZA763580B (en) 1975-07-08 1976-06-16 New chemical compounds
GR51105A GR60429B (en) 1975-07-08 1976-06-25 Preparation process of new compounds with diuretic and/or saluretic activity
AT473076A AT345783B (de) 1975-07-08 1976-06-29 Verfahren zur herstellung von neuen substituierten 3-aminomethylbenzolsulfonamiden sowie deren saeureadditionssalzen
PT65317A PT65317B (en) 1975-07-08 1976-07-02 Method for the preparation of new chemical compounds
SU762377347A SU644374A3 (ru) 1975-07-08 1976-07-02 Способ получени производных сульфамилбензиламина или их солей
DK302776A DK302776A (da) 1975-07-08 1976-07-05 Fremgangsmade til fremstilling af hidtil ukendte substituerede 5-sulfamylbenzylaminer
CA256,326A CA1077953A (en) 1975-07-08 1976-07-05 Method for producing new chemical compounds
JP7956776A JPS5212147A (en) 1975-07-08 1976-07-06 Novel chemical compound
BE168670A BE843828A (fr) 1975-07-08 1976-07-06 Nouveaux composes utiles en medecine humaine et veterinaire et procedes de leur preparation
NL7607505A NL7607505A (nl) 1975-07-08 1976-07-07 Werkwijze voor de bereiding van sulfamylbenzyl- aminen.
ES449648A ES449648A1 (es) 1975-07-08 1976-07-07 Metodo para producir nuevas 3,4-disustituidas 5-sulfamilben-zilaminas.
FI761987A FI761987A7 (enExample) 1975-07-08 1976-07-07
LU75322A LU75322A1 (enExample) 1975-07-08 1976-07-07
IT7668697A IT1063145B (it) 1975-07-08 1976-07-07 Procedimento per la preparazione di originali composti ad uso medicina le e veterinario
SE7607786A SE7607786L (sv) 1975-07-08 1976-07-07 Forfarande for framstellning av sulfamylbensylforeningar
DE2630637A DE2630637C2 (de) 1975-07-08 1976-07-07 Sulfamylbenzylaminderivate, Verfahren zu ihrer Herstellung und Arzneimittel, die diese Verbindungen enthalten
FR7620790A FR2316929A1 (fr) 1975-07-08 1976-07-07 Nouveaux composes utiles en medecine humaine et veterinaire et procedes de leur preparation
AU15677/76A AU503344B2 (en) 1975-07-08 1976-07-07 Substituted sufamylbenzylamines
US05/862,976 US4247550A (en) 1975-07-08 1977-12-21 Compositions and methods for the treatment of hypertension or oedemas
IE2496/78A IE43010B1 (en) 1975-07-08 1978-12-18 Sulfonamide derivatives

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB2877375 1975-07-08
GB2877575 1975-07-08
GB2877475 1975-07-08
GB28770/75A GB1523631A (en) 1975-07-08 1975-07-08 Sulphonamide derivatives
GB2877275 1975-07-08

Publications (1)

Publication Number Publication Date
GB1523631A true GB1523631A (en) 1978-09-06

Family

ID=27516295

Family Applications (1)

Application Number Title Priority Date Filing Date
GB28770/75A Expired GB1523631A (en) 1975-07-08 1975-07-08 Sulphonamide derivatives

Country Status (19)

Country Link
US (1) US4082851A (enExample)
AT (1) AT345783B (enExample)
AU (1) AU503344B2 (enExample)
BE (1) BE843828A (enExample)
CA (1) CA1077953A (enExample)
DE (1) DE2630637C2 (enExample)
DK (1) DK302776A (enExample)
FI (1) FI761987A7 (enExample)
FR (1) FR2316929A1 (enExample)
GB (1) GB1523631A (enExample)
GR (1) GR60429B (enExample)
IE (1) IE43009B1 (enExample)
IT (1) IT1063145B (enExample)
LU (1) LU75322A1 (enExample)
NL (1) NL7607505A (enExample)
NZ (1) NZ181168A (enExample)
PT (1) PT65317B (enExample)
SE (1) SE7607786L (enExample)
SU (1) SU644374A3 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8084442B2 (en) 2005-05-13 2011-12-27 Otsuka Pharmaceutical Co., Ltd. N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4247550A (en) * 1975-07-08 1981-01-27 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Compositions and methods for the treatment of hypertension or oedemas
CH628622A5 (de) * 1976-12-24 1982-03-15 Ciba Geigy Ag Verfahren zur herstellung von neuen in 4-stellung substituierten 3-sulfamoylbenzoesaeuren.
GB1600840A (en) * 1978-05-30 1981-10-21 Wellcome Found Diphenylether derivatives useful as flukicidal agents
DE3041812A1 (de) * 1980-11-06 1982-06-16 Hoechst Ag, 6000 Frankfurt Basisch substituierte 5-phenyltetrazole, verfahren zu ihrer herstellung und ihre verwendung als heilmittel
DE3208189A1 (de) * 1982-03-06 1983-09-08 Hoechst Ag, 6230 Frankfurt 2-aminomethyl-6-sulfamoylphenolderivate, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
MXPA01009733A (es) * 1999-03-31 2002-11-04 Basf Ag Diamidas del acido piridin-2,3-dicarboxilico.
SK542007A3 (sk) * 2007-04-20 2008-11-06 Unimed Pharma, Spol. S R. O. Substituované sulfónamidy, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2871233A (en) * 1954-06-16 1959-01-27 Basf Ag Cobalt containing azo dyestuffs
US3565920A (en) * 1966-12-29 1971-02-23 Ciba Geigy Corp 5-sulfamyl-anthranilic acids
US3565952A (en) * 1968-09-06 1971-02-23 Beiersdorf Ag 4 - chloro - 3 - nitro - 5 - sulfamyl salicylic acid - (2',6' - dimethyl) - anilide and its salts
GB1249490A (en) * 1968-12-24 1971-10-13 Leo Pharm Prod Ltd New sulphamyl-benzoic acid derivatives
US3806542A (en) * 1969-06-10 1974-04-23 Ciba Geigy Corp 5-arylsulfamyl-anthranilic acids
US3706790A (en) * 1970-02-27 1972-12-19 Merck & Co Inc (mono-and di-substituted sulfamoyl) benzoic acids
US3816482A (en) * 1970-06-18 1974-06-11 Leo Pharm Prod Ltd Sulfamylbenzoic acids
US3860647A (en) * 1973-08-20 1975-01-14 Smithkline Corp {60 -Aminomethyl-4-hydroxy-3-sulfamyl-benzyl alcohols and 4-hydroxy-3-sulfamyl phenethylamines
GB1434405A (en) * 1973-09-06 1976-05-05 Leo Pharm Prod Ltd Phenyl-benzoic acid derivatives

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8084442B2 (en) 2005-05-13 2011-12-27 Otsuka Pharmaceutical Co., Ltd. N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors
US8420623B2 (en) 2005-05-13 2013-04-16 Otsuka Pharmaceutical Co., Ltd. N, N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors
US8815871B2 (en) 2005-05-13 2014-08-26 Otsuka Pharmaceutical Co., Ltd. N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors
US9611214B2 (en) 2005-05-13 2017-04-04 Otsuka Pharmaceutical Co., Ltd. N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors
US10000450B2 (en) 2005-05-13 2018-06-19 Otsuka Pharmaceutical Co., Ltd. N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors

Also Published As

Publication number Publication date
FR2316929A1 (fr) 1977-02-04
DE2630637C2 (de) 1986-09-25
FI761987A7 (enExample) 1977-01-09
AU503344B2 (en) 1979-08-30
NL7607505A (nl) 1977-01-11
IE43009B1 (en) 1980-12-03
ATA473076A (de) 1978-02-15
FR2316929B1 (enExample) 1979-09-21
AT345783B (de) 1978-10-10
NZ181168A (en) 1978-09-25
DE2630637A1 (de) 1977-01-27
LU75322A1 (enExample) 1977-04-01
IE43009L (en) 1977-01-08
GR60429B (en) 1978-05-26
SE7607786L (sv) 1977-01-09
CA1077953A (en) 1980-05-20
PT65317A (en) 1976-08-01
US4082851A (en) 1978-04-04
SU644374A3 (ru) 1979-01-25
AU1567776A (en) 1978-01-12
IT1063145B (it) 1985-02-11
PT65317B (en) 1978-01-05
DK302776A (da) 1977-01-09
BE843828A (fr) 1977-01-06

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee