GB1511682A - 9-dihydroniddamycin a compounds and related 3-(o)-esters and a process for their preparation - Google Patents
9-dihydroniddamycin a compounds and related 3-(o)-esters and a process for their preparationInfo
- Publication number
- GB1511682A GB1511682A GB19963/75A GB1996375A GB1511682A GB 1511682 A GB1511682 A GB 1511682A GB 19963/75 A GB19963/75 A GB 19963/75A GB 1996375 A GB1996375 A GB 1996375A GB 1511682 A GB1511682 A GB 1511682A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkanoyl
- dihydroniddamycin
- niddamycin
- och
- cho
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- IEMDOFXTVAPVLX-YWQHLDGFSA-N Leucomycin A1 Chemical compound CO[C@H]1[C@H](O)CC(=O)O[C@H](C)C\C=C\C=C\[C@H](O)[C@H](C)C[C@H](CC=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](N(C)C)[C@H](O[C@@H]2O[C@@H](C)[C@H](OC(=O)CC(C)C)[C@](C)(O)C2)[C@@H](C)O1 IEMDOFXTVAPVLX-YWQHLDGFSA-N 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title 1
- SPEUIVXLLWOEMJ-UHFFFAOYSA-N 1,1-dimethoxyethane Chemical compound COC(C)OC SPEUIVXLLWOEMJ-UHFFFAOYSA-N 0.000 abstract 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 6
- REPPNUPKOJKPSP-ZZNWINOMSA-N Niddamycin Chemical compound CO[C@H]1[C@H](O)CC(=O)O[C@H](C)C\C=C\C=C\C(=O)[C@H](C)C[C@H](CC=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](N(C)C)[C@H](O[C@@H]2O[C@@H](C)[C@H](OC(=O)C(C)C)[C@](C)(O)C2)[C@@H](C)O1 REPPNUPKOJKPSP-ZZNWINOMSA-N 0.000 abstract 3
- PXUIVECFRJIQIG-UHFFFAOYSA-N Niddamycin Natural products COC1C(CC(CC(C)C(=O)C=CC=C/CC(C)OC(=O)CC1OC(=O)C)C=O)OC2OC(C)C(OC3CC(C)(O)C(OC(=O)CC(C)C)C(C)O3)C(C2O)N(C)C PXUIVECFRJIQIG-UHFFFAOYSA-N 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 3
- 125000002252 acyl group Chemical group 0.000 abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 239000000010 aprotic solvent Substances 0.000 abstract 2
- 230000003301 hydrolyzing effect Effects 0.000 abstract 2
- 125000002861 (C1-C4) alkanoyl group Chemical group 0.000 abstract 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 abstract 1
- 150000008065 acid anhydrides Chemical class 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/476,015 US3932383A (en) | 1974-06-03 | 1974-06-03 | 9-Dihydroniddamycin A compounds and related 3-(O)-esters and the process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1511682A true GB1511682A (en) | 1978-05-24 |
Family
ID=23890144
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB19963/75A Expired GB1511682A (en) | 1974-06-03 | 1975-05-12 | 9-dihydroniddamycin a compounds and related 3-(o)-esters and a process for their preparation |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3932383A (https=) |
| JP (1) | JPS514190A (https=) |
| CA (1) | CA1048018A (https=) |
| FR (1) | FR2288095A1 (https=) |
| GB (1) | GB1511682A (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1624999A (en) * | 1997-12-24 | 1999-07-19 | Teresa J. Ingram | Compositions comprising equisetum and symphytum and methods for the treatment of symptoms associated with mycoplasma infection |
| US6440942B1 (en) * | 2000-12-22 | 2002-08-27 | Enanta Pharmaceuticals, Inc. | 14-membered macrolides derived from leucomycins |
| US6462026B1 (en) * | 2001-02-16 | 2002-10-08 | Enanta Pharmaceuticals, Inc. | Bicyclic leucomycins |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3792035A (en) * | 1970-05-04 | 1974-02-12 | Meiji Seika Kaisha | Mono-acetyl derivatives of antibiotic sf-837 and sf-837-a2 substances and production thereof |
| US3784447A (en) * | 1972-04-17 | 1974-01-08 | Abbott Lab | Mycarosyl macrolide antibiotics |
-
1974
- 1974-06-03 US US05/476,015 patent/US3932383A/en not_active Expired - Lifetime
-
1975
- 1975-05-12 GB GB19963/75A patent/GB1511682A/en not_active Expired
- 1975-06-02 CA CA228,210A patent/CA1048018A/en not_active Expired
- 1975-06-02 JP JP50065459A patent/JPS514190A/ja active Pending
- 1975-06-03 FR FR7517320A patent/FR2288095A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2288095A1 (fr) | 1976-05-14 |
| CA1048018A (en) | 1979-02-06 |
| FR2288095B1 (https=) | 1981-08-07 |
| US3932383A (en) | 1976-01-13 |
| JPS514190A (en) | 1976-01-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] |