GB1510092A - Derivatives of vincaminic acid hydrazide - Google Patents
Derivatives of vincaminic acid hydrazideInfo
- Publication number
- GB1510092A GB1510092A GB27295/76A GB2729576A GB1510092A GB 1510092 A GB1510092 A GB 1510092A GB 27295/76 A GB27295/76 A GB 27295/76A GB 2729576 A GB2729576 A GB 2729576A GB 1510092 A GB1510092 A GB 1510092A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid hydrazide
- vincaminic
- derivatives
- reacting
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
1510092 Derivatives of vincaminic acid hydrazide MERRELL TORAUDE 30 June 1976 [1 July 1975] 27295/76 Heading C2C Novel compounds of the Formula I and acid addition salts thereof may be prepared by reacting vincaminic acid hydrazide with a halide, anhydride or ester of a pyridine carboxylic acid, and optionally forming an acid addition salt from the product. Vincaminic acid hydrazide is prepared by reacting vincamine with hydrazine. Pharmaceutical compositions of the compounds I with the usual excipients show moderate hypotensive activity and act as vasodilates in the treatment of cerebral and peripheral vascular insufficiences when administered parenterally or orally.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7520662A FR2315928A1 (en) | 1975-07-01 | 1975-07-01 | NEW DERIVATIVES OF VINCAMIC HYDRAZIDE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1510092A true GB1510092A (en) | 1978-05-10 |
Family
ID=9157345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB27295/76A Expired GB1510092A (en) | 1975-07-01 | 1976-06-30 | Derivatives of vincaminic acid hydrazide |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS603078B2 (en) |
| BE (1) | BE843618A (en) |
| DE (1) | DE2624973A1 (en) |
| ES (1) | ES449390A1 (en) |
| FR (1) | FR2315928A1 (en) |
| GB (1) | GB1510092A (en) |
-
1975
- 1975-07-01 FR FR7520662A patent/FR2315928A1/en active Granted
-
1976
- 1976-06-03 DE DE19762624973 patent/DE2624973A1/en not_active Ceased
- 1976-06-30 ES ES449390A patent/ES449390A1/en not_active Expired
- 1976-06-30 GB GB27295/76A patent/GB1510092A/en not_active Expired
- 1976-06-30 BE BE168493A patent/BE843618A/en not_active IP Right Cessation
- 1976-07-01 JP JP51077095A patent/JPS603078B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES449390A1 (en) | 1977-08-01 |
| DE2624973A1 (en) | 1977-01-27 |
| FR2315928B1 (en) | 1978-10-06 |
| BE843618A (en) | 1976-10-18 |
| FR2315928A1 (en) | 1977-01-28 |
| JPS528000A (en) | 1977-01-21 |
| JPS603078B2 (en) | 1985-01-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19940630 |