GB1508978A - Esters of clavulanic acid - Google Patents
Esters of clavulanic acidInfo
- Publication number
- GB1508978A GB1508978A GB3656377A GB3656377A GB1508978A GB 1508978 A GB1508978 A GB 1508978A GB 3656377 A GB3656377 A GB 3656377A GB 3656377 A GB3656377 A GB 3656377A GB 1508978 A GB1508978 A GB 1508978A
- Authority
- GB
- United Kingdom
- Prior art keywords
- clavulanic acid
- penicillin
- april
- ester
- esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1508978 Antibiotic compositions containing clavulanic acid esters BEECHAM GROUP Ltd 11 April 1975 [20 April 1974 21 June 1974 9 Oct 1974 11 Dec 1974] 36563/77 36564/77 36565/77 and 36566/77 Divided out of 1508977 Heading A5B [Also in Division C2] Pharmceutical compositions having antibacterial and #-lactamase inhibitory properties comprise, as active ingredient, an ester (formed at the carboxyl group) of clavulanic acid of the formula together with a pharmaceutically acceptable carrier and optionally therapeutic agents such as a penicillin or cephalosporin, e.g. benzylpenicillin, phenoxymethyl - penicillin, carbenicillin, methicillin, propicillin, ampicillin, amoxycillin, epicillin, ticarcillin, cyolacillin, cephaloridine, cephalothin, cefazolin, cephalexin, cephacetrile, cephamandole, cephapirin, cephradine, cephaloglycine or a salt or in vivo hydrolysable ester thereof or an aldehyde or ketone adduct of such a compound having a 6- or 7 - α - amino - acylamido side chain. They may be administered, orally, topically or parenterally, e.g. as tablets, capsules, creams, syrups, suspensions, solutions, reconstitutable powders and sterile forms suitable for injection or infusion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3656377A GB1508978A (en) | 1975-04-11 | 1975-04-11 | Esters of clavulanic acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3656377A GB1508978A (en) | 1975-04-11 | 1975-04-11 | Esters of clavulanic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1508978A true GB1508978A (en) | 1978-04-26 |
Family
ID=10389283
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3656377A Expired GB1508978A (en) | 1975-04-11 | 1975-04-11 | Esters of clavulanic acid |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1508978A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0672670A1 (en) | 1992-06-11 | 1995-09-20 | Smithkline Beecham Plc | Process for the preparation of clavulanic acid |
| WO1997010247A1 (en) * | 1995-09-15 | 1997-03-20 | Smithkline Beecham P.L.C. | Clavulanic acid derivatives for treating atherosclerosis |
| US5859238A (en) * | 1992-03-26 | 1999-01-12 | Lek, Tovarna Farmacevtskih | Alkylenediammonium diclavulanate derivatives, a process for the preparation thereof as well as the use thereof |
-
1975
- 1975-04-11 GB GB3656377A patent/GB1508978A/en not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5859238A (en) * | 1992-03-26 | 1999-01-12 | Lek, Tovarna Farmacevtskih | Alkylenediammonium diclavulanate derivatives, a process for the preparation thereof as well as the use thereof |
| EP0672670A1 (en) | 1992-06-11 | 1995-09-20 | Smithkline Beecham Plc | Process for the preparation of clavulanic acid |
| WO1997010247A1 (en) * | 1995-09-15 | 1997-03-20 | Smithkline Beecham P.L.C. | Clavulanic acid derivatives for treating atherosclerosis |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 704A | Declaration that licence is not available as of right for an excepted use (par. 4a/1977) | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19950410 |