GB1508745A - Steroidal(16alpha,17-d)cyclohexenes - Google Patents
Steroidal(16alpha,17-d)cyclohexenesInfo
- Publication number
- GB1508745A GB1508745A GB2947/76A GB294776A GB1508745A GB 1508745 A GB1508745 A GB 1508745A GB 2947/76 A GB2947/76 A GB 2947/76A GB 294776 A GB294776 A GB 294776A GB 1508745 A GB1508745 A GB 1508745A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cyclohexenes
- acyloxy
- steroids
- halo
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001935 cyclohexenes Chemical class 0.000 title 1
- 230000003637 steroidlike Effects 0.000 title 1
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 150000003431 steroids Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 238000005698 Diels-Alder reaction Methods 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000596 cyclohexenyl group Chemical class C1(=CCCCC1)* 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003862 glucocorticoid Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/546,647 US3944584A (en) | 1975-02-03 | 1975-02-03 | Steroidal (16α,17-d)cyclohexenes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1508745A true GB1508745A (en) | 1978-04-26 |
Family
ID=24181368
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2947/76A Expired GB1508745A (en) | 1975-02-03 | 1976-01-26 | Steroidal(16alpha,17-d)cyclohexenes |
Country Status (6)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3994935A (en) * | 1975-11-24 | 1976-11-30 | E. R. Squibb & Sons, Inc. | Steroidal 16β-alkyl[16α,17-b]naphthalenes |
| US4091036A (en) * | 1977-05-12 | 1978-05-23 | E. R. Squibb & Sons, Inc. | 17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16 α, 17 α-b]naphthalenes and derivatives |
| US4160772A (en) * | 1978-06-26 | 1979-07-10 | E. R. Squibb & Sons, Inc. | Steroidal[16α,17-d]cyclohexene-21-carboxylic acid esters |
| NZ190510A (en) * | 1978-06-26 | 1982-03-09 | Squibb & Sons Inc | Steroidal (16 ,17-d) cyclohexene and (16 ,17-b) naphthaleno-21-carboxylic acids and esters |
| US4213912A (en) * | 1979-04-26 | 1980-07-22 | E. R. Squibb & Sons, Inc. | Process for preparing steroidal [16α,17-d]cyclohexene-21-carboxylic acid esters |
| US4219488A (en) * | 1979-04-26 | 1980-08-26 | E. R. Squibb & Sons, Inc. | Process for preparing steroidal [16α,17-b]naphthaleno-21-carboxylic acid esters |
| US4446071A (en) * | 1982-09-09 | 1984-05-01 | E. R. Squibb & Sons, Inc. | Intermediates useful in the preparation of 17,17-bis(substituted thio) androstenes |
| EP0123735A1 (en) * | 1983-04-29 | 1984-11-07 | Gist-Brocades N.V. | New process for the preparation of 20-keto-delta-16-steroids and new intermediate compounds formed in this process |
| US4474702A (en) * | 1984-01-20 | 1984-10-02 | E. R. Squibb & Sons, Inc. | [16,17-a]Cyclopentano pregnenes |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH81A (de) * | 1889-01-09 | Louis Giroud | Kniehebelpresse mit Handkurbelantrieb, Zahnradübersetzung und Zugstange, hauptsächlich zur Herstellung von Bausteinen | |
| CH79A (de) * | 1889-01-09 | Adam Sautter Johann | Uhrwerk für Taschenuhren mit offenem Federhaus, neuem Gangrücker-System und vereinfachter Werkbefestigung |
-
1975
- 1975-02-03 US US05/546,647 patent/US3944584A/en not_active Expired - Lifetime
-
1976
- 1976-01-14 CA CA243,573A patent/CA1064477A/en not_active Expired
- 1976-01-26 GB GB2947/76A patent/GB1508745A/en not_active Expired
- 1976-02-02 FR FR7602785*[A patent/FR2299035A1/fr active Granted
- 1976-02-03 JP JP51011219A patent/JPS591280B2/ja not_active Expired
- 1976-02-03 DE DE2604055A patent/DE2604055A1/de not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JPS51101971A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-09-08 |
| FR2299035A1 (fr) | 1976-08-27 |
| DE2604055A1 (de) | 1976-08-05 |
| CA1064477A (en) | 1979-10-16 |
| FR2299035B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1979-08-24 |
| JPS591280B2 (ja) | 1984-01-11 |
| US3944584A (en) | 1976-03-16 |
Similar Documents
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| Kondo et al. | Microbiological Synthesis of 16-Keto Steroids from Steroidal Sapogenins | |
| US2867637A (en) | 6alpha methyl, 9alpha f, 17alpha oh 1, 4 pregnadiene compounds | |
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| GB1512400A (en) | Steroidal naphthalenes | |
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| GB924931A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
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| Kaufmann et al. | 21-Hydroxylation of pregnenolone by microsomal preparations of rat and human adrenals | |
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| GB1192824A (en) | Improvements in or relating to 6,7-Methylene and -Halomethylene Steroids | |
| Lewbart | Reactions of. alpha.-ketols and other 21-hydroxy steroids with phosgene. IV. Formation of 20-chloro-17, 20-cyclic carbonates from 17. alpha.-hydroxy-20-ones | |
| US3201394A (en) | Lactol derivatives of 16-(2-oxo ethyl)-17-hydroxy pregnane steroids |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| 704A | Declaration that licence is not available as of right for an excepted use (par. 4a/1977) | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19960125 |