GB1505275A - Cephalosporins - Google Patents

Cephalosporins

Info

Publication number
GB1505275A
GB1505275A GB20663/75A GB2066375A GB1505275A GB 1505275 A GB1505275 A GB 1505275A GB 20663/75 A GB20663/75 A GB 20663/75A GB 2066375 A GB2066375 A GB 2066375A GB 1505275 A GB1505275 A GB 1505275A
Authority
GB
United Kingdom
Prior art keywords
alkyl
phenyl
compound
derivative
oxopyridyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB20663/75A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/495,598 external-priority patent/US4171435A/en
Priority claimed from US05/513,978 external-priority patent/US4003893A/en
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of GB1505275A publication Critical patent/GB1505275A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00Thiols, sulfides, hydropolysulfides or polysulfides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1505275 Cephalosporin derivatives E R SQUIBB & SONS Inc 15 May 1975 [8 Aug 1974 11 Oct 1974] 20663/75 Heading C2C [Also in Division C3] Novel compounds I (R is H, 1-7C alkyl, phenyl-1-7C alkyl; an alkali metal, alkaline earth metal or alkylamine cation; or -CH(R 6 )-OCOR 5 ; R 1 is H, 1-7C alkyl, phenyl, thienyl or furyl; R 2 and R 6 are H or 1-7C alkyl; R 3 and R 5 are 1-7C alkyl, phenyl or phenyl-1-7C alkyl; R 4 is H, OH, alkanoyloxy, or -SR<SP>1</SP> 4 ; and R 4 <SP>1</SP> is oxadiazolyl, thiadiazolyl, thiatriazolyl, tetrazolyl, 1-oxopyridyl or a 1-7C alkyl derivative of the heterocyclyl radical) are prepared by reaction of a compound II with an acid III or a derivative thereof. Pharmaceutical compositions useful as antibacterial agents comprise a compound I together with a suitable excipient.
GB20663/75A 1974-08-08 1975-05-15 Cephalosporins Expired GB1505275A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/495,598 US4171435A (en) 1974-08-08 1974-08-08 [(Thioalkyl)thioacetyl)]cephalosporin derivatives
US05/513,978 US4003893A (en) 1974-10-11 1974-10-11 3-Heterothio[(thioalkyl)thioacetyl]cephalosporanic derivatives

Publications (1)

Publication Number Publication Date
GB1505275A true GB1505275A (en) 1978-03-30

Family

ID=27051821

Family Applications (1)

Application Number Title Priority Date Filing Date
GB20663/75A Expired GB1505275A (en) 1974-08-08 1975-05-15 Cephalosporins

Country Status (4)

Country Link
JP (1) JPS6119634B2 (en)
DE (1) DE2535130A1 (en)
FR (1) FR2281121A1 (en)
GB (1) GB1505275A (en)

Also Published As

Publication number Publication date
JPS6119634B2 (en) 1986-05-17
DE2535130A1 (en) 1976-02-19
FR2281121A1 (en) 1976-03-05
FR2281121B1 (en) 1980-04-30
JPS5141386A (en) 1976-04-07

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee