GB1503577A - Vincadioline - Google Patents
VincadiolineInfo
- Publication number
- GB1503577A GB1503577A GB18323/75A GB1832375A GB1503577A GB 1503577 A GB1503577 A GB 1503577A GB 18323/75 A GB18323/75 A GB 18323/75A GB 1832375 A GB1832375 A GB 1832375A GB 1503577 A GB1503577 A GB 1503577A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkaloid
- vincadioline
- novel
- heading
- termed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- CTODJDOCNIIUTR-UHFFFAOYSA-N Vincadioline Natural products CCC1(O)CC2CN(CCc3c([nH]c4ccccc34)C(C2)(C(=O)OC)c5cc6c(cc5OC)N(C)C7(O)C(O)(C(OC(=O)C)C8(CC)C=CCN9CCC67C89)C(=O)OC)C1 CTODJDOCNIIUTR-UHFFFAOYSA-N 0.000 title abstract 2
- IFGMHVGAHYXLIZ-UHFFFAOYSA-N methyl 11-acetyloxy-12-ethyl-4-(17-ethyl-16,17-dihydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl)-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate Chemical compound OC1C(CC)(O)CN(CCC=2C3=CC=CC=C3NC=22)CC1CC2(C(=O)OC)C1=CC(C23C(C(C(OC(C)=O)C4(CC)C=CCN(C34)CC2)(O)C(=O)OC)N2C)=C2C=C1OC IFGMHVGAHYXLIZ-UHFFFAOYSA-N 0.000 title abstract 2
- 229930013930 alkaloid Natural products 0.000 abstract 3
- 150000003797 alkaloid derivatives Chemical class 0.000 abstract 3
- 240000001829 Catharanthus roseus Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003080 antimitotic agent Substances 0.000 abstract 1
- 229940041181 antineoplastic drug Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US466939A US3887565A (en) | 1974-05-06 | 1974-05-06 | Vincadioline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1503577A true GB1503577A (en) | 1978-03-15 |
Family
ID=23853659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB18323/75A Expired GB1503577A (en) | 1974-05-06 | 1975-05-02 | Vincadioline |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3887565A (en, 2012) |
| JP (1) | JPS50154406A (en, 2012) |
| BE (1) | BE828211A (en, 2012) |
| CA (1) | CA1060891A (en, 2012) |
| CH (1) | CH613708A5 (en, 2012) |
| DE (1) | DE2519533A1 (en, 2012) |
| FR (1) | FR2269942B1 (en, 2012) |
| GB (1) | GB1503577A (en, 2012) |
| HU (1) | HU170135B (en, 2012) |
| IE (1) | IE40837B1 (en, 2012) |
| IL (1) | IL46877A (en, 2012) |
| NL (1) | NL7505348A (en, 2012) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4115388A (en) * | 1977-03-30 | 1978-09-19 | Eli Lilly And Company | 3'-Oxygenated derivatives of 4'-deoxy VLB "A" and "B" and related 1-formyl compounds |
| US4110330A (en) * | 1977-05-27 | 1978-08-29 | Eli Lilly And Company | 5'-Acetonylvincristine and related compounds |
| US4166810A (en) * | 1978-04-20 | 1979-09-04 | Eli Lilly And Company | Derivatives of 4-desacetyl VLB C-3 carboxyhydrazide |
| US6326402B1 (en) | 1998-08-12 | 2001-12-04 | Octamer, Inc. | Methods for treating viral infections using a compound capable of inhibiting microtubules |
| EP2266607A3 (en) | 1999-10-01 | 2011-04-20 | Immunogen, Inc. | Immunoconjugates for treating cancer |
| US8858953B2 (en) * | 2011-05-09 | 2014-10-14 | Yu-Hwa Peter Sheng | Herbal composition for treating cancer |
-
1974
- 1974-05-06 US US466939A patent/US3887565A/en not_active Expired - Lifetime
-
1975
- 1975-03-18 IE IE585/75A patent/IE40837B1/xx unknown
- 1975-03-20 IL IL46877A patent/IL46877A/en unknown
- 1975-04-21 JP JP50048559A patent/JPS50154406A/ja active Pending
- 1975-04-22 BE BE1006605A patent/BE828211A/xx unknown
- 1975-04-22 FR FR7512531A patent/FR2269942B1/fr not_active Expired
- 1975-04-23 CA CA225,299A patent/CA1060891A/en not_active Expired
- 1975-04-29 CH CH546475A patent/CH613708A5/xx not_active IP Right Cessation
- 1975-05-02 GB GB18323/75A patent/GB1503577A/en not_active Expired
- 1975-05-02 DE DE19752519533 patent/DE2519533A1/de not_active Withdrawn
- 1975-05-05 HU HUEI616A patent/HU170135B/hu unknown
- 1975-05-06 NL NL7505348A patent/NL7505348A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HU170135B (en, 2012) | 1977-04-28 |
| IL46877A0 (en) | 1975-05-22 |
| IE40837B1 (en) | 1979-08-29 |
| IE40837L (en) | 1975-11-06 |
| FR2269942A1 (en, 2012) | 1975-12-05 |
| CA1060891A (en) | 1979-08-21 |
| NL7505348A (nl) | 1975-11-10 |
| CH613708A5 (en, 2012) | 1979-10-15 |
| FR2269942B1 (en, 2012) | 1978-08-04 |
| US3887565A (en) | 1975-06-03 |
| JPS50154406A (en, 2012) | 1975-12-12 |
| BE828211A (fr) | 1975-10-22 |
| IL46877A (en) | 1977-12-30 |
| DE2519533A1 (de) | 1975-11-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |