GB1500063A - Indolinone and fluorenone derivatives - Google Patents
Indolinone and fluorenone derivativesInfo
- Publication number
- GB1500063A GB1500063A GB25530/75A GB2553075A GB1500063A GB 1500063 A GB1500063 A GB 1500063A GB 25530/75 A GB25530/75 A GB 25530/75A GB 2553075 A GB2553075 A GB 2553075A GB 1500063 A GB1500063 A GB 1500063A
- Authority
- GB
- United Kingdom
- Prior art keywords
- indolinone
- fluorenone
- fluorenone derivatives
- het
- june
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
- C07D203/10—Radicals substituted by singly bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH838174A CH602710A5 (en) | 1974-06-19 | 1974-06-19 | Substd. 9-fluorenone and 2-indolinone derivs |
CH838074A CH599160A5 (en) | 1974-06-19 | 1974-06-19 | Substd. 9-fluorenone and 2-indolinone derivs |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1500063A true GB1500063A (en) | 1978-02-08 |
Family
ID=25703229
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB25530/75A Expired GB1500063A (en) | 1974-06-19 | 1975-06-16 | Indolinone and fluorenone derivatives |
Country Status (18)
Country | Link |
---|---|
JP (1) | JPS51125060A (fr) |
AT (1) | ATA466375A (fr) |
AU (1) | AU8216875A (fr) |
CA (1) | CA1036163A (fr) |
DD (1) | DD118086A5 (fr) |
DE (1) | DE2525656A1 (fr) |
DK (1) | DK259475A (fr) |
ES (1) | ES438637A1 (fr) |
FI (1) | FI751727A (fr) |
FR (1) | FR2275200A1 (fr) |
GB (1) | GB1500063A (fr) |
HU (1) | HU169926B (fr) |
IE (1) | IE41562B1 (fr) |
IL (1) | IL47503A0 (fr) |
NL (1) | NL7507131A (fr) |
NO (1) | NO752078L (fr) |
SE (1) | SE7506757L (fr) |
SU (1) | SU583755A3 (fr) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0005828A1 (fr) * | 1978-06-06 | 1979-12-12 | Hoechst Aktiengesellschaft | Nouvelles dérivés de la phénylpipérazine substitués, médicaments les contenant et procédés pour leur préparation |
US6911439B2 (en) | 1999-01-22 | 2005-06-28 | Elan Pharmaceuticals, Inc. | Heteroaryl, heterocyclic and aryl compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US7579466B2 (en) | 2006-02-27 | 2009-08-25 | Elan Pharmaceuticals, Inc. | Pyrimidinyl sulfonamide compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US7727996B2 (en) | 2005-09-29 | 2010-06-01 | Elan Pharmaceuticals, Inc. | Carbamate compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US7763632B2 (en) | 2005-09-29 | 2010-07-27 | Elan Pharmaceuticals, Inc. | Pyrimidinyl amide compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US8367836B2 (en) | 2009-04-27 | 2013-02-05 | Elan Pharmaceuticals, Inc. | Pyridinone antagonists of alpha-4 integrins |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI281470B (en) | 2002-05-24 | 2007-05-21 | Elan Pharm Inc | Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins |
TW200307671A (en) | 2002-05-24 | 2003-12-16 | Elan Pharm Inc | Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins |
-
1975
- 1975-06-09 DE DE19752525656 patent/DE2525656A1/de active Pending
- 1975-06-10 FI FI751727A patent/FI751727A/fi unknown
- 1975-06-10 DK DK259475A patent/DK259475A/da unknown
- 1975-06-11 NO NO752078A patent/NO752078L/no unknown
- 1975-06-12 SE SE7506757A patent/SE7506757L/xx unknown
- 1975-06-16 NL NL7507131A patent/NL7507131A/xx not_active Application Discontinuation
- 1975-06-16 GB GB25530/75A patent/GB1500063A/en not_active Expired
- 1975-06-17 ES ES438637A patent/ES438637A1/es not_active Expired
- 1975-06-17 AU AU82168/75A patent/AU8216875A/en not_active Expired
- 1975-06-17 DD DD186699A patent/DD118086A5/xx unknown
- 1975-06-17 IE IE1359/75A patent/IE41562B1/en unknown
- 1975-06-17 HU HUSA2805A patent/HU169926B/hu unknown
- 1975-06-17 IL IL47503A patent/IL47503A0/xx unknown
- 1975-06-17 FR FR7518882A patent/FR2275200A1/fr active Granted
- 1975-06-18 AT AT466375A patent/ATA466375A/de not_active Application Discontinuation
- 1975-06-18 JP JP50073280A patent/JPS51125060A/ja active Pending
- 1975-06-18 CA CA229,607A patent/CA1036163A/fr not_active Expired
- 1975-06-19 SU SU7502145931A patent/SU583755A3/ru active
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0005828A1 (fr) * | 1978-06-06 | 1979-12-12 | Hoechst Aktiengesellschaft | Nouvelles dérivés de la phénylpipérazine substitués, médicaments les contenant et procédés pour leur préparation |
US6911439B2 (en) | 1999-01-22 | 2005-06-28 | Elan Pharmaceuticals, Inc. | Heteroaryl, heterocyclic and aryl compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US7005433B2 (en) | 1999-01-22 | 2006-02-28 | Elan Pharmaceuticals, Inc. | Heteroaryl, heterocyclic and aryl compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US7973044B2 (en) | 1999-01-22 | 2011-07-05 | Elan Pharmaceuticals, Inc. | Heteroaryl, heterocyclic and aryl compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US7968547B2 (en) | 1999-01-22 | 2011-06-28 | Elan Pharmaceuticals, Inc. | Heteroaryl, heterocyclic and aryl compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US7741328B2 (en) | 1999-01-22 | 2010-06-22 | Elan Pharmaceuticals, Inc. | Heteroaryl, heterocyclic and aryl compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US7763632B2 (en) | 2005-09-29 | 2010-07-27 | Elan Pharmaceuticals, Inc. | Pyrimidinyl amide compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US7727996B2 (en) | 2005-09-29 | 2010-06-01 | Elan Pharmaceuticals, Inc. | Carbamate compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US8158642B2 (en) | 2005-09-29 | 2012-04-17 | Elan Pharmaceuticals, Inc. | Carbamate compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US8367688B2 (en) | 2005-09-29 | 2013-02-05 | Elan Pharmaceuticals, Inc. | Carbamate compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US7820687B2 (en) | 2006-02-27 | 2010-10-26 | Elan Pharmaceuticals, Inc. | Pyrimidinyl sulfonamide compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US7579466B2 (en) | 2006-02-27 | 2009-08-25 | Elan Pharmaceuticals, Inc. | Pyrimidinyl sulfonamide compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US8367836B2 (en) | 2009-04-27 | 2013-02-05 | Elan Pharmaceuticals, Inc. | Pyridinone antagonists of alpha-4 integrins |
Also Published As
Publication number | Publication date |
---|---|
AU8216875A (en) | 1976-12-23 |
FR2275200B1 (fr) | 1979-06-08 |
IE41562B1 (en) | 1980-01-30 |
DK259475A (da) | 1975-12-20 |
IL47503A0 (en) | 1975-08-31 |
ES438637A1 (es) | 1977-06-01 |
FI751727A (fr) | 1975-12-20 |
SU583755A3 (ru) | 1977-12-05 |
DE2525656A1 (de) | 1976-01-15 |
NL7507131A (nl) | 1975-12-23 |
NO752078L (fr) | 1975-12-22 |
FR2275200A1 (fr) | 1976-01-16 |
HU169926B (fr) | 1977-02-28 |
DD118086A5 (fr) | 1976-02-12 |
CA1036163A (fr) | 1978-08-08 |
JPS51125060A (en) | 1976-11-01 |
IE41562L (en) | 1975-12-19 |
SE7506757L (sv) | 1975-12-22 |
ATA466375A (de) | 1979-08-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |