GB1496759A - Cephalosporin derivatives - Google Patents
Cephalosporin derivativesInfo
- Publication number
- GB1496759A GB1496759A GB3700677A GB3700677A GB1496759A GB 1496759 A GB1496759 A GB 1496759A GB 3700677 A GB3700677 A GB 3700677A GB 3700677 A GB3700677 A GB 3700677A GB 1496759 A GB1496759 A GB 1496759A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- dec
- derivatives
- syn
- blocking group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
- C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Abstract
1496759 Cephalosporin derivatives GLAXO LABORATORIES Ltd 20 Dec 1974 [21 Dec 1973] 37006/77 Divided out of 1496757 Heading C2C Novel compounds I (R is H or methyl) and salts or derivatives thereof, the compounds being syn isomers or mixtures of syn and anti isomers containing at least 90% of the former, are prepared by reaction of a compound II or a salt or N-silyl derivative thereof with a compound III in the form of an acylation agent (B is S or SO; R<SP>19</SP> is H or a blocking group and R<SP>20</SP> is a blocking group) or by carbamoylation of a compound IV followed where necessary by conventional modifications. Pharmaceutical compositions comprise a compound I together with a diluent or carrier and are useful as antibiotics.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3700677A GB1496759A (en) | 1974-12-20 | 1974-12-20 | Cephalosporin derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3700677A GB1496759A (en) | 1974-12-20 | 1974-12-20 | Cephalosporin derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1496759A true GB1496759A (en) | 1978-01-05 |
Family
ID=10392953
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3700677A Expired GB1496759A (en) | 1974-12-20 | 1974-12-20 | Cephalosporin derivatives |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1496759A (en) |
-
1974
- 1974-12-20 GB GB3700677A patent/GB1496759A/en not_active Expired
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |