GB1494625A - Pharmaceutical preparations - Google Patents
Pharmaceutical preparationsInfo
- Publication number
- GB1494625A GB1494625A GB5068/74A GB506874A GB1494625A GB 1494625 A GB1494625 A GB 1494625A GB 5068/74 A GB5068/74 A GB 5068/74A GB 506874 A GB506874 A GB 506874A GB 1494625 A GB1494625 A GB 1494625A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkaloid
- vincamine
- feb
- pharmaceutical preparations
- preparations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- RXPRRQLKFXBCSJ-GIVPXCGWSA-N vincamine Chemical class C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C[C@](O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-GIVPXCGWSA-N 0.000 abstract 3
- 238000002360 preparation method Methods 0.000 abstract 2
- WYJAPUKIYAZSEM-MOPGFXCFSA-N Eburnamonine Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)CC(=O)N5C2=C1 WYJAPUKIYAZSEM-MOPGFXCFSA-N 0.000 abstract 1
- UJYGDMFEEDNVBF-UHFFFAOYSA-N Ergocorninine Natural products C1=CC(C=2C(N(C)CC(C=2)C(=O)NC2(C(=O)N3C(C(N4CCCC4C3(O)O2)=O)C(C)C)C(C)C)C2)=C3C2=CNC3=C1 UJYGDMFEEDNVBF-UHFFFAOYSA-N 0.000 abstract 1
- AFVFQIVMOAPDHO-UHFFFAOYSA-M Methanesulfonate Chemical compound CS([O-])(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-M 0.000 abstract 1
- 229930013930 alkaloid Natural products 0.000 abstract 1
- 150000003797 alkaloid derivatives Chemical class 0.000 abstract 1
- YDOTUXAWKBPQJW-UHFFFAOYSA-N alpha-Ergocryptinine Natural products C1=CC(C=2C(N(C)CC(C=2)C(=O)NC2(C(=O)N3C(C(N4CCCC4C3(O)O2)=O)CC(C)C)C(C)C)C2)=C3C2=CNC3=C1 YDOTUXAWKBPQJW-UHFFFAOYSA-N 0.000 abstract 1
- YDOTUXAWKBPQJW-NSLWYYNWSA-N alpha-ergocryptine Chemical compound C1=CC(C=2[C@H](N(C)C[C@@H](C=2)C(=O)N[C@]2(C(=O)N3[C@H](C(N4CCC[C@H]4[C@]3(O)O2)=O)CC(C)C)C(C)C)C2)=C3C2=CNC3=C1 YDOTUXAWKBPQJW-NSLWYYNWSA-N 0.000 abstract 1
- 229950001817 alpha-ergocryptine Drugs 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 229960004318 dihydroergocristine Drugs 0.000 abstract 1
- DEQITUUQPICUMR-HJPBWRTMSA-N dihydroergocristine Chemical compound C([C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](C(N21)=O)(NC(=O)[C@H]1CN(C)[C@H]2[C@@H](C=3C=CC=C4NC=C(C=34)C2)C1)C(C)C)C1=CC=CC=C1 DEQITUUQPICUMR-HJPBWRTMSA-N 0.000 abstract 1
- RXPRRQLKFXBCSJ-UHFFFAOYSA-N dl-Vincamin Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)CC(O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- XQUUDUKVJKNJNP-OGGGUQDZSA-N ergocornine Chemical compound C([C@H]1N(C)C2)C([C]34)=CN=C4C=CC=C3C1=C[C@H]2C(=O)N[C@@]1(C(C)C)C(=O)N2[C@@H](C(C)C)C(=O)N3CCC[C@H]3[C@]2(O)O1 XQUUDUKVJKNJNP-OGGGUQDZSA-N 0.000 abstract 1
- OWEUDBYTKOYTAD-MKTPKCENSA-N ergocristine Chemical compound C([C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](C(N21)=O)(NC(=O)[C@@H]1C=C2C3=CC=CC4=NC=C([C]34)C[C@H]2N(C)C1)C(C)C)C1=CC=CC=C1 OWEUDBYTKOYTAD-MKTPKCENSA-N 0.000 abstract 1
- HEFIYUQVAZFDEE-UHFFFAOYSA-N ergocristinine Natural products N12C(=O)C(C(C)C)(NC(=O)C3C=C4C=5C=CC=C6NC=C(C=56)CC4N(C)C3)OC2(O)C2CCCN2C(=O)C1CC1=CC=CC=C1 HEFIYUQVAZFDEE-UHFFFAOYSA-N 0.000 abstract 1
- 229960003133 ergot alkaloid Drugs 0.000 abstract 1
- 150000003840 hydrochlorides Chemical class 0.000 abstract 1
- 239000006194 liquid suspension Substances 0.000 abstract 1
- 150000004701 malic acid derivatives Chemical class 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- WYJAPUKIYAZSEM-UHFFFAOYSA-N rac-Eburnamonin Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)CC(=O)N5C2=C1 WYJAPUKIYAZSEM-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 150000003892 tartrate salts Chemical class 0.000 abstract 1
- 229960002922 vinburnine Drugs 0.000 abstract 1
- 229960002726 vincamine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5068/74A GB1494625A (en) | 1974-02-04 | 1974-02-04 | Pharmaceutical preparations |
| US05/546,444 US3987173A (en) | 1974-02-04 | 1975-02-03 | Pharmaceutical preparations comprising vincamine alkaloids and dihydroergocristine |
| DE19752504387 DE2504387A1 (de) | 1974-02-04 | 1975-02-03 | Arzneimittelgemisch |
| NL7501278A NL7501278A (nl) | 1974-02-04 | 1975-02-04 | Mengsels van een ergot en een vincamine. |
| FR7503406A FR2259609B1 (https=) | 1974-02-04 | 1975-02-04 | |
| BE153066A BE825188A (fr) | 1974-02-04 | 1975-02-04 | Composition therapeurique d'une vincamine et d'un alcaloide de l'ergot pour l'amelioration de la circulation cerebrale |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5068/74A GB1494625A (en) | 1974-02-04 | 1974-02-04 | Pharmaceutical preparations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1494625A true GB1494625A (en) | 1977-12-07 |
Family
ID=9789155
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5068/74A Expired GB1494625A (en) | 1974-02-04 | 1974-02-04 | Pharmaceutical preparations |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3987173A (https=) |
| BE (1) | BE825188A (https=) |
| DE (1) | DE2504387A1 (https=) |
| FR (1) | FR2259609B1 (https=) |
| GB (1) | GB1494625A (https=) |
| NL (1) | NL7501278A (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2525433C2 (ru) * | 2011-10-05 | 2014-08-10 | Общество С Ограниченной Ответственностью "Фарма Старт" | Лекарственный препарат винкамина в форме матричных таблеток для улучшения мозгового кровообращения и способ его изготовления |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4315937A (en) * | 1979-11-28 | 1982-02-16 | Sandoz Ltd. | Ergots and their use in treating minimal brain dysfunction |
| DE3227122A1 (de) * | 1982-07-20 | 1984-01-26 | Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim | Stabile loesungen von mutterkornalkaloiden |
| US7771746B2 (en) * | 1999-12-03 | 2010-08-10 | Polichem Sa | Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2108993A1 (en) | 1970-10-28 | 1972-05-26 | Forschag | Vincamine alkaloid fraction - with sedative and vasoregulating effect |
-
1974
- 1974-02-04 GB GB5068/74A patent/GB1494625A/en not_active Expired
-
1975
- 1975-02-03 US US05/546,444 patent/US3987173A/en not_active Expired - Lifetime
- 1975-02-03 DE DE19752504387 patent/DE2504387A1/de not_active Withdrawn
- 1975-02-04 FR FR7503406A patent/FR2259609B1/fr not_active Expired
- 1975-02-04 NL NL7501278A patent/NL7501278A/xx not_active Application Discontinuation
- 1975-02-04 BE BE153066A patent/BE825188A/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2525433C2 (ru) * | 2011-10-05 | 2014-08-10 | Общество С Ограниченной Ответственностью "Фарма Старт" | Лекарственный препарат винкамина в форме матричных таблеток для улучшения мозгового кровообращения и способ его изготовления |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2259609A1 (https=) | 1975-08-29 |
| NL7501278A (nl) | 1975-08-06 |
| DE2504387A1 (de) | 1975-08-07 |
| FR2259609B1 (https=) | 1978-07-21 |
| US3987173A (en) | 1976-10-19 |
| BE825188A (fr) | 1975-08-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |