GB1491863A - 2,5-or 2,6-disubstituted benzoxazoles - Google Patents
2,5-or 2,6-disubstituted benzoxazolesInfo
- Publication number
- GB1491863A GB1491863A GB49260/73A GB4926073A GB1491863A GB 1491863 A GB1491863 A GB 1491863A GB 49260/73 A GB49260/73 A GB 49260/73A GB 4926073 A GB4926073 A GB 4926073A GB 1491863 A GB1491863 A GB 1491863A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- convert
- alkyl
- reacting
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 2,6-disubstituted benzoxazoles Chemical class 0.000 title abstract 6
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 7
- 125000002560 nitrile group Chemical group 0.000 abstract 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- 125000000355 1,3-benzoxazolyl group Chemical class O1C(=NC2=C1C=CC=C2)* 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 3
- 125000002252 acyl group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 3
- CDAWCLOXVUBKRW-UHFFFAOYSA-N 2-aminophenol Chemical compound NC1=CC=CC=C1O CDAWCLOXVUBKRW-UHFFFAOYSA-N 0.000 abstract 2
- NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical compound C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 230000003301 hydrolyzing effect Effects 0.000 abstract 2
- 150000002825 nitriles Chemical class 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 abstract 1
- VFRDBQGBQYINBH-UHFFFAOYSA-N 2-(2,6-dichlorophenyl)acetyl chloride Chemical compound ClC(=O)CC1=C(Cl)C=CC=C1Cl VFRDBQGBQYINBH-UHFFFAOYSA-N 0.000 abstract 1
- YOCRMABISPGUSN-UHFFFAOYSA-N 2-(3-amino-4-hydroxyphenyl)propanenitrile Chemical compound N#CC(C)C1=CC=C(O)C(N)=C1 YOCRMABISPGUSN-UHFFFAOYSA-N 0.000 abstract 1
- VMZCDNSFRSVYKQ-UHFFFAOYSA-N 2-phenylacetyl chloride Chemical compound ClC(=O)CC1=CC=CC=C1 VMZCDNSFRSVYKQ-UHFFFAOYSA-N 0.000 abstract 1
- 125000006577 C1-C6 hydroxyalkyl group Chemical group 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001414 amino alcohols Chemical class 0.000 abstract 1
- UAZDIGCOBKKMPU-UHFFFAOYSA-O azanium;azide Chemical compound [NH4+].[N-]=[N+]=[N-] UAZDIGCOBKKMPU-UHFFFAOYSA-O 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- UOQQYQILJGCDCO-UHFFFAOYSA-N n-[5-(1-cyanoethyl)-2-hydroxyphenyl]-2-phenylacetamide Chemical compound N#CC(C)C1=CC=C(O)C(NC(=O)CC=2C=CC=CC=2)=C1 UOQQYQILJGCDCO-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (26)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB49260/73A GB1491863A (en) | 1973-10-23 | 1973-10-23 | 2,5-or 2,6-disubstituted benzoxazoles |
| AR256198A AR207232A1 (es) | 1973-10-23 | 1974-01-01 | Procedimiento para preparar un derivado benzoxazolico |
| ZA00746341A ZA746341B (en) | 1973-10-23 | 1974-10-04 | 2,5 and 2,6 disubstituted benzoxazoles |
| IL45837A IL45837A (en) | 1973-10-23 | 1974-10-11 | Alpha-(2-substituted-5(or 6)-benzoxazolyl)alkanoic acid derivatives their preparation and pharmaceutical compositions containing them |
| CS747094A CS188927B2 (en) | 1973-10-23 | 1974-10-16 | Method of producing derivatives of 2-benzyl benzoxale |
| AU74546/74A AU486943B2 (en) | 1973-10-23 | 1974-10-21 | 2, 5 or 2, 6-disubstituted benzoxazoles |
| BG028005A BG26197A3 (bg) | 1973-10-23 | 1974-10-21 | Метод за получаване на 2,5- и 2,6-дисубституирани бензоксазоли |
| IE2168/74A IE40080B1 (en) | 1973-10-23 | 1974-10-22 | 2,5- or 2,6-disubstituted benzoxazoles |
| HULI265A HU170452B (enrdf_load_stackoverflow) | 1973-10-23 | 1974-10-22 | |
| SU7402074061A SU577992A3 (ru) | 1973-10-23 | 1974-10-22 | Способ получени производных бензоксазола |
| DE19742450042 DE2450042A1 (de) | 1973-10-23 | 1974-10-22 | Neue benzoxazolderivate und verfahren zu ihrer herstellung |
| CA212,029A CA1038393A (en) | 1973-10-23 | 1974-10-22 | 2,5 or 2,6 disubstituted benzoxazoles |
| BE6044793A BE821350A (fr) | 1973-10-23 | 1974-10-22 | Derives de benzoxazole a substitution 2 |
| FR7435407A FR2248039B1 (enrdf_load_stackoverflow) | 1973-10-23 | 1974-10-22 | |
| NL7413788A NL7413788A (nl) | 1973-10-23 | 1974-10-22 | Werkwijze voor de bereiding van biologisch actieve benzoxazolen, werkwijze voor de be- reiding van een gevormd geneesmiddel en een dergelijk geneesmiddel. |
| RO7480290A RO72841A (ro) | 1973-10-23 | 1974-10-22 | Procedeu de preparare a derivatilor de benzoxazol |
| CH1414374A CH605863A5 (enrdf_load_stackoverflow) | 1973-10-23 | 1974-10-22 | |
| AT849374A AT341519B (de) | 1973-10-23 | 1974-10-22 | Verfahren zur herstellung von neuen benzoxazolderivaten |
| DK552774A DK552774A (enrdf_load_stackoverflow) | 1973-10-23 | 1974-10-22 | |
| PL1974175042A PL94057B1 (enrdf_load_stackoverflow) | 1973-10-23 | 1974-10-23 | |
| SE7413352A SE7413352L (enrdf_load_stackoverflow) | 1973-10-23 | 1974-10-23 | |
| ES431299A ES431299A1 (es) | 1973-10-22 | 1974-10-23 | Procedimiento para evaluar la lisura de un anodo. un procedimiento para preparar un derivado del benzoxazol. |
| DD181873A DD114609A5 (enrdf_load_stackoverflow) | 1973-10-23 | 1974-10-23 | |
| JP49122355A JPS5070362A (enrdf_load_stackoverflow) | 1973-10-23 | 1974-10-23 | |
| AR259897A AR207369A1 (es) | 1973-10-23 | 1975-01-01 | Un producto intermedio que es un derivado de benzoxasol util para la preparacion de benzoxazoles |
| US05/655,668 US4025637A (en) | 1973-10-23 | 1976-02-04 | 2,5 OR 2,6 Disubstituted benzoxazoles |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB49260/73A GB1491863A (en) | 1973-10-23 | 1973-10-23 | 2,5-or 2,6-disubstituted benzoxazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1491863A true GB1491863A (en) | 1977-11-16 |
Family
ID=10451725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB49260/73A Expired GB1491863A (en) | 1973-10-22 | 1973-10-23 | 2,5-or 2,6-disubstituted benzoxazoles |
Country Status (22)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1435721A (en) * | 1972-05-18 | 1976-05-12 | Lilly Industries Ltd | Benzoxazole derivatives |
| US3888864A (en) | 1973-06-29 | 1975-06-10 | Hoffmann La Roche | Amino lower alkyl ether derivatives of opium alkaloids |
| IT1099589B (it) * | 1978-08-04 | 1985-09-18 | Ravizza Spa | Processo per la preparazione di derivati dell'acido benzoxazolil propionico |
| IT1157295B (it) * | 1982-07-19 | 1987-02-11 | Ravizza Spa | Processo perfezionato per la preparazione di derivati dell'acido benzoxazolil propionico |
| JPH03173874A (ja) * | 1989-09-29 | 1991-07-29 | Mitsubishi Kasei Corp | 新規複素環化合物 |
| DE102006021878A1 (de) * | 2006-05-11 | 2007-11-15 | Sanofi-Aventis | Phenylamino-benzoxazol substituierte Carbonsäuren, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
-
1973
- 1973-10-23 GB GB49260/73A patent/GB1491863A/en not_active Expired
-
1974
- 1974-01-01 AR AR256198A patent/AR207232A1/es active
- 1974-10-04 ZA ZA00746341A patent/ZA746341B/xx unknown
- 1974-10-11 IL IL45837A patent/IL45837A/xx unknown
- 1974-10-16 CS CS747094A patent/CS188927B2/cs unknown
- 1974-10-21 BG BG028005A patent/BG26197A3/xx unknown
- 1974-10-22 IE IE2168/74A patent/IE40080B1/xx unknown
- 1974-10-22 BE BE6044793A patent/BE821350A/xx unknown
- 1974-10-22 NL NL7413788A patent/NL7413788A/xx not_active Application Discontinuation
- 1974-10-22 DK DK552774A patent/DK552774A/da unknown
- 1974-10-22 AT AT849374A patent/AT341519B/de not_active IP Right Cessation
- 1974-10-22 HU HULI265A patent/HU170452B/hu unknown
- 1974-10-22 SU SU7402074061A patent/SU577992A3/ru active
- 1974-10-22 CA CA212,029A patent/CA1038393A/en not_active Expired
- 1974-10-22 FR FR7435407A patent/FR2248039B1/fr not_active Expired
- 1974-10-22 RO RO7480290A patent/RO72841A/ro unknown
- 1974-10-22 DE DE19742450042 patent/DE2450042A1/de not_active Withdrawn
- 1974-10-22 CH CH1414374A patent/CH605863A5/xx not_active IP Right Cessation
- 1974-10-23 SE SE7413352A patent/SE7413352L/xx unknown
- 1974-10-23 JP JP49122355A patent/JPS5070362A/ja active Pending
- 1974-10-23 PL PL1974175042A patent/PL94057B1/pl unknown
- 1974-10-23 DD DD181873A patent/DD114609A5/xx unknown
-
1975
- 1975-01-01 AR AR259897A patent/AR207369A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| ATA849374A (de) | 1977-06-15 |
| AT341519B (de) | 1978-02-10 |
| DE2450042A1 (de) | 1975-04-24 |
| AR207232A1 (es) | 1976-09-22 |
| FR2248039B1 (enrdf_load_stackoverflow) | 1978-07-28 |
| DD114609A5 (enrdf_load_stackoverflow) | 1975-08-12 |
| PL94057B1 (enrdf_load_stackoverflow) | 1977-07-30 |
| CH605863A5 (enrdf_load_stackoverflow) | 1978-10-13 |
| ZA746341B (en) | 1976-06-30 |
| FR2248039A1 (enrdf_load_stackoverflow) | 1975-05-16 |
| CA1038393A (en) | 1978-09-12 |
| IE40080B1 (en) | 1979-03-14 |
| JPS5070362A (enrdf_load_stackoverflow) | 1975-06-11 |
| BE821350A (fr) | 1975-04-22 |
| BG26197A3 (bg) | 1979-02-15 |
| DK552774A (enrdf_load_stackoverflow) | 1975-06-16 |
| RO72841A (ro) | 1982-05-10 |
| AU7454674A (en) | 1976-04-29 |
| HU170452B (enrdf_load_stackoverflow) | 1977-06-28 |
| CS188927B2 (en) | 1979-03-30 |
| NL7413788A (nl) | 1975-04-25 |
| IE40080L (en) | 1975-04-23 |
| SU577992A3 (ru) | 1977-10-25 |
| IL45837A (en) | 1978-03-10 |
| AR207369A1 (es) | 1976-09-30 |
| IL45837A0 (en) | 1974-12-31 |
| SE7413352L (enrdf_load_stackoverflow) | 1975-04-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1435721A (en) | Benzoxazole derivatives | |
| KR850001179A (ko) | 류코트리엔 길항제의 제조방법 | |
| BR8102426A (pt) | Processo para preparacao de cianetos de aclla | |
| GB1491863A (en) | 2,5-or 2,6-disubstituted benzoxazoles | |
| ES253662A1 (es) | Procedimiento para la preparacion de derivados de la fenilalanina | |
| GB1314801A (en) | Isoxazolopyrimidine derivatives and their use as herbicides | |
| GB1139940A (en) | Oxazole derivatives | |
| GB1137529A (en) | Thiazole compositions | |
| GB1354939A (en) | Process for the manufacture of 1,1,2-triphenylalk-1-enes | |
| GB1435722A (en) | O-aminophenol derivatives | |
| GB1038344A (en) | New benzo aza-cycloalkenes | |
| IE32086B1 (en) | Oxazole derivatives | |
| GB1427693A (en) | 4,5-dihydro-1,2,4-oxadiazoles | |
| GB1095236A (en) | N-carboxyalkyl-(2-methylene alkanoyl) aniline derivatives | |
| GB1152885A (en) | Indazole-3-yl-Oxyalkanoic Acids and process for the preparation thereof | |
| YU10496A (sh) | Postupak za proizvodnju oksazolidinona novi oksazolidinoni kao i primena oksazolidinona | |
| IE40077B1 (en) | Benzoxazoles | |
| GB980251A (en) | New piperazine derivatives | |
| ES350186A1 (es) | Procedimiento para la preparacion de derivados de furazan. | |
| GB817745A (en) | 2-thiohydantoins | |
| GB664550A (en) | Stabilizers for photographic emulsions | |
| BE794639A (en) | Phenoxy-alkyloxy-4-oxo-4h-1-benzopyran-2-carboxylic - acids and-2-yl tetrazoles - anaphylactic slow reacting substance anta | |
| GB1272269A (en) | beta-PHENYL-ACRYLIC ACID NITRILES | |
| FR2313917A1 (fr) | Nouveaux agents de contraste radiographique constitues par les derives de l'acide n-acetyl n-(diamino-3,5 triiodo-2,4,6 phenyl) b-aminopropionique, leurs intermediaires de synthese et leur preparation | |
| GB1030391A (en) | Improvements in or relating to intermediates of use in the production of cephalosporins |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |