GB1490466A - Compositions for the detection of fibrinogen fibrinogen split products and/or fibrin split products - Google Patents

Compositions for the detection of fibrinogen fibrinogen split products and/or fibrin split products

Info

Publication number
GB1490466A
GB1490466A GB6135/76A GB613576A GB1490466A GB 1490466 A GB1490466 A GB 1490466A GB 6135/76 A GB6135/76 A GB 6135/76A GB 613576 A GB613576 A GB 613576A GB 1490466 A GB1490466 A GB 1490466A
Authority
GB
United Kingdom
Prior art keywords
fibrinogen
cells
dyed
dyestuff
killed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB6135/76A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of GB1490466A publication Critical patent/GB1490466A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/305—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F)
    • G01N2333/31—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/75—Fibrin; Fibrinogen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/882—Staphylococcus
    • Y10S435/883—Staphylococcus aureus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

1490466 Detection of fibrinogen &c. using dyed Staph. aurens WARNER-LAMBERT CO 17 Feb 1976 [7 March 1975] 06135/76 Heading GIB A compositions for determining fibrinogen, fibrin split products and fibrinogen split products in blood comprises an imiazole buffer suspension of killed Staphylococcus aurens cells dyed with a triphenyl tetrazolium chloride dyestuff or with fast Black Salt K. (a diazo-salt of 2, 5-dimethoxy-4- [(4-P-nitrophenyl)-azo] -benzenamine). The dyestuff may be 2, 3, 5-triphenyl tetrazolium chloride, 2- (P-iodophenyl)-3-(P-nitrophenyl)-5-phenyltetrazolium chloride or 3, 3<SP>1</SP>-dimethoxy-4,4<SP>1</SP>- biphenylene)-bis-(2, 5-diphenyl-2H-tetrazolium chloride). A saline solution of the dyestuff may be added to the fermentation broth in the presence of a polyalkylene glycol molecular weight from 1000 to 5000, then the killed dyed cells are washed free of unused dyestuff. When fast Black Salt K is used it is added to a suspension of the killed cells. The killed dyed cells suspended in imidazole buffer may be lyophilized. In use in the determination of fibrinogen etc.; aliquots of the dyed cells are added to serial dilutions of the serum under test in wells of a microtitre plate and the wells inspected for clumping of the cells.
GB6135/76A 1975-03-07 1976-02-17 Compositions for the detection of fibrinogen fibrinogen split products and/or fibrin split products Expired GB1490466A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/556,504 US3990947A (en) 1975-03-07 1975-03-07 Composition for detecting fibrinogen, fibrinogen split products and fibrin split products

Publications (1)

Publication Number Publication Date
GB1490466A true GB1490466A (en) 1977-11-02

Family

ID=24221614

Family Applications (1)

Application Number Title Priority Date Filing Date
GB6135/76A Expired GB1490466A (en) 1975-03-07 1976-02-17 Compositions for the detection of fibrinogen fibrinogen split products and/or fibrin split products

Country Status (15)

Country Link
US (1) US3990947A (en)
JP (1) JPS51117095A (en)
AU (1) AU507738B2 (en)
BE (1) BE839145A (en)
CA (1) CA1061229A (en)
DE (1) DE2608733A1 (en)
DK (1) DK95676A (en)
FR (1) FR2303291A1 (en)
GB (1) GB1490466A (en)
IE (1) IE42640B1 (en)
IT (1) IT1057927B (en)
LU (1) LU74498A1 (en)
NL (1) NL7602094A (en)
NO (1) NO760768L (en)
SE (1) SE7602866L (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2197468A (en) * 1986-09-19 1988-05-18 Yissum Res Dev Co Immunoassay reagents, kits and methods

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2525804B2 (en) * 1975-06-10 1980-04-03 Behringwerke Ag, 3550 Marburg Stable clumping factor, use of the same for the detection of fibrinogen and fibrin breakdown products and production of the same
DE2644622C3 (en) * 1976-10-02 1979-11-29 Behringwerke Ag, 3550 Marburg Extraction of microorganisms and diagnostic agents containing them
US4567137A (en) * 1983-01-20 1986-01-28 Philpot Van B Serum thrombin time in clinical medicine
US4461830A (en) * 1983-01-20 1984-07-24 Buren Philpot V Jun Serum fibrinogen viscosity in clinical medicine
JPS62502262A (en) * 1985-03-27 1987-09-03 ブロンコスタット・プロプライアタリー・リミテツド Vaccines without adjuvants
DD261844A1 (en) * 1986-07-09 1988-11-09 Adw Ddr METHOD FOR PRACTICING FIBRINMONOMERS
US5424193A (en) * 1993-02-25 1995-06-13 Quidel Corporation Assays employing dyed microorganism labels
CN110257475B (en) * 2019-06-28 2023-05-02 深圳市国赛生物技术有限公司 Fibrinogen detection reagent, preparation method thereof and detection reagent product

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3881993A (en) * 1971-03-16 1975-05-06 Miles Lab Testing device for microorganisms
US3834991A (en) * 1972-05-23 1974-09-10 Warner Lambert Co Colorimetric assay for lysozyme
US3790447A (en) * 1972-07-05 1974-02-05 Abbott Lab Streptococci diagnostic method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2197468A (en) * 1986-09-19 1988-05-18 Yissum Res Dev Co Immunoassay reagents, kits and methods
GB2197468B (en) * 1986-09-19 1991-03-13 Yissum Res Dev Co Immunoassay methods and kits

Also Published As

Publication number Publication date
BE839145A (en) 1976-07-01
JPS5523080B2 (en) 1980-06-20
US3990947A (en) 1976-11-09
LU74498A1 (en) 1976-09-01
CA1061229A (en) 1979-08-28
AU1172776A (en) 1977-09-08
FR2303291B1 (en) 1980-08-01
IT1057927B (en) 1982-03-30
JPS51117095A (en) 1976-10-14
IE42640L (en) 1976-09-07
AU507738B2 (en) 1980-02-28
FR2303291A1 (en) 1976-10-01
DK95676A (en) 1976-09-08
NO760768L (en) 1976-09-08
IE42640B1 (en) 1980-09-24
SE7602866L (en) 1976-09-08
DE2608733A1 (en) 1976-09-16
NL7602094A (en) 1976-09-09

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee