GB1489989A - Alpha,alpha-diaryl-beta-(tert-amino)-propanols processes for their preparation and pharmaceutical compositions containing them - Google Patents
Alpha,alpha-diaryl-beta-(tert-amino)-propanols processes for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- GB1489989A GB1489989A GB8236/75A GB823675A GB1489989A GB 1489989 A GB1489989 A GB 1489989A GB 8236/75 A GB8236/75 A GB 8236/75A GB 823675 A GB823675 A GB 823675A GB 1489989 A GB1489989 A GB 1489989A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alpha
- propanols
- diaryl
- tert
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 3
- 125000001424 substituent group Chemical group 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 1
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- FKLJPTJMIBLJAV-UHFFFAOYSA-N Compound IV Chemical compound O1N=C(C)C=C1CCCCCCCOC1=CC=C(C=2OCCN=2)C=C1 FKLJPTJMIBLJAV-UHFFFAOYSA-N 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- 150000001335 aliphatic alkanes Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- NLFBCYMMUAKCPC-KQQUZDAGSA-N ethyl (e)-3-[3-amino-2-cyano-1-[(e)-3-ethoxy-3-oxoprop-1-enyl]sulfanyl-3-oxoprop-1-enyl]sulfanylprop-2-enoate Chemical compound CCOC(=O)\C=C\SC(=C(C#N)C(N)=O)S\C=C\C(=O)OCC NLFBCYMMUAKCPC-KQQUZDAGSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 230000000894 saliuretic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2410284A DE2410284C3 (de) | 1974-03-04 | 1974-03-04 | Verwendung von mehrfach substituierten α , α -Diphenyl-β -(tert. amino)-propanolen bei der saluretischen Therapie |
| DE2508203A DE2508203C2 (de) | 1975-02-26 | 1975-02-26 | Verwendung von mehrfach substituierten α,α-Diphenyl-β-(tert.-amino)-propanolen bei der saluretischen Therapie |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1489989A true GB1489989A (en) | 1977-10-26 |
Family
ID=25766732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB8236/75A Expired GB1489989A (en) | 1974-03-04 | 1975-02-27 | Alpha,alpha-diaryl-beta-(tert-amino)-propanols processes for their preparation and pharmaceutical compositions containing them |
Country Status (13)
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL93401C (US08197722-20120612-C00042.png) * | 1954-10-23 | |||
| GB993525A (en) * | 1961-05-19 | 1965-05-26 | Smith Kline French Lab | Substituted propanolamines and process for preparing the same |
-
1975
- 1975-02-27 SE SE7502248A patent/SE415973B/xx unknown
- 1975-02-27 GB GB8236/75A patent/GB1489989A/en not_active Expired
- 1975-03-03 DK DK83975*#A patent/DK83975A/da not_active Application Discontinuation
- 1975-03-03 US US05/554,902 patent/US4025633A/en not_active Expired - Lifetime
- 1975-03-04 NL NL7502530A patent/NL7502530A/xx not_active Application Discontinuation
- 1975-03-04 CH CH270575A patent/CH612170A5/xx not_active IP Right Cessation
- 1975-03-04 ES ES435291A patent/ES435291A1/es not_active Expired
- 1975-03-04 BE BE153950A patent/BE826235A/xx not_active IP Right Cessation
- 1975-03-04 CA CA221,228A patent/CA1047514A/en not_active Expired
- 1975-03-04 FR FR7506760A patent/FR2262973B1/fr not_active Expired
- 1975-03-04 DD DD184552A patent/DD117674A5/xx unknown
-
1978
- 1978-12-30 MY MY241/78A patent/MY7800241A/xx unknown
-
1979
- 1979-05-03 HK HK292/79A patent/HK29279A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE415973B (sv) | 1980-11-17 |
| US4025633A (en) | 1977-05-24 |
| FR2262973B1 (US08197722-20120612-C00042.png) | 1980-01-04 |
| ES435291A1 (es) | 1977-04-01 |
| FR2262973A1 (US08197722-20120612-C00042.png) | 1975-10-03 |
| CH612170A5 (US08197722-20120612-C00042.png) | 1979-07-13 |
| DD117674A5 (US08197722-20120612-C00042.png) | 1976-01-20 |
| CA1047514A (en) | 1979-01-30 |
| BE826235A (fr) | 1975-06-30 |
| SE7502248L (US08197722-20120612-C00042.png) | 1975-09-05 |
| DK83975A (US08197722-20120612-C00042.png) | 1975-09-05 |
| NL7502530A (nl) | 1975-09-08 |
| MY7800241A (en) | 1978-12-31 |
| HK29279A (en) | 1979-05-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |