GB1483250A - Production of 6-aminopenicillins and 7-aminocephalosporin - Google Patents

Production of 6-aminopenicillins and 7-aminocephalosporin

Info

Publication number
GB1483250A
GB1483250A GB5490174A GB5490174A GB1483250A GB 1483250 A GB1483250 A GB 1483250A GB 5490174 A GB5490174 A GB 5490174A GB 5490174 A GB5490174 A GB 5490174A GB 1483250 A GB1483250 A GB 1483250A
Authority
GB
United Kingdom
Prior art keywords
formula
compound
solvolysis
subjecting
aminocephalosporin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5490174A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of GB1483250A publication Critical patent/GB1483250A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

6-Aminopenam and 7-aminocephem compounds of the formula H<2>N-A are prepared by subjecting a compound of the formula R<1>-C(SR<2>)=N-A, in which R<1> represents an organic radical and R<2> represents a substituted mercapto group, to a solvolysis or by reacting a compound of the formula R<1>-CS-NH-A with a sulphidising agent to give the compound of the second formula given above and subjecting the latter to a solvolysis. The compounds are obtained in good yield, if desired in the one-pot process. They are intermediates for the synthesis of antibiotics of the penicillin and cephalosporin series.
GB5490174A 1973-12-28 1974-12-19 Production of 6-aminopenicillins and 7-aminocephalosporin Expired GB1483250A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP743181A JPS5629672B2 (en) 1973-12-28 1973-12-28

Publications (1)

Publication Number Publication Date
GB1483250A true GB1483250A (en) 1977-08-17

Family

ID=11550204

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5490174A Expired GB1483250A (en) 1973-12-28 1974-12-19 Production of 6-aminopenicillins and 7-aminocephalosporin

Country Status (7)

Country Link
JP (1) JPS5629672B2 (en)
CA (1) CA1060434A (en)
CH (1) CH615188A5 (en)
DE (1) DE2460332A1 (en)
FR (1) FR2272094A1 (en)
GB (1) GB1483250A (en)
NL (1) NL7416970A (en)

Also Published As

Publication number Publication date
NL7416970A (en) 1975-07-01
JPS5096591A (en) 1975-07-31
CH615188A5 (en) 1980-01-15
FR2272094A1 (en) 1975-12-19
CA1060434A (en) 1979-08-14
DE2460332A1 (en) 1975-07-10
JPS5629672B2 (en) 1981-07-09

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee