GB1482048A - Oxatricyclooctane derivatives for use in the synthesis of prostaglandins - Google Patents
Oxatricyclooctane derivatives for use in the synthesis of prostaglandinsInfo
- Publication number
- GB1482048A GB1482048A GB4889476A GB4889476A GB1482048A GB 1482048 A GB1482048 A GB 1482048A GB 4889476 A GB4889476 A GB 4889476A GB 4889476 A GB4889476 A GB 4889476A GB 1482048 A GB1482048 A GB 1482048A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- alkyl
- oxatricyclooctanes
- racemates
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 title 1
- 150000003180 prostaglandins Chemical class 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- -1 Bicyclo[3, 1 ,0]hex - 2 - ene - 6 - carboxaldehyde acetals Chemical class 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 150000001299 aldehydes Chemical class 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 150000003935 benzaldehydes Chemical class 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
- 150000002334 glycols Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000006303 photolysis reaction Methods 0.000 abstract 1
- 230000015843 photosynthesis, light reaction Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
- C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
- C07C35/27—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system containing six carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48829574A | 1974-07-12 | 1974-07-12 | |
| US55270775A | 1975-02-24 | 1975-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1482048A true GB1482048A (en) | 1977-08-03 |
Family
ID=27049301
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2494075A Expired GB1482047A (en) | 1974-07-12 | 1975-06-11 | Bicyclohexane derivatives for use in the synthesis of prostaglandins |
| GB4889576A Expired GB1482049A (en) | 1974-07-12 | 1975-06-11 | Bicyclohexane derivatives for use in the synthesis of prostaglandins |
| GB4889476A Expired GB1482048A (en) | 1974-07-12 | 1975-06-11 | Oxatricyclooctane derivatives for use in the synthesis of prostaglandins |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2494075A Expired GB1482047A (en) | 1974-07-12 | 1975-06-11 | Bicyclohexane derivatives for use in the synthesis of prostaglandins |
| GB4889576A Expired GB1482049A (en) | 1974-07-12 | 1975-06-11 | Bicyclohexane derivatives for use in the synthesis of prostaglandins |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS5134146A (xx) |
| CH (2) | CH619922A5 (xx) |
| DE (1) | DE2530221A1 (xx) |
| FR (3) | FR2285385A1 (xx) |
| GB (3) | GB1482047A (xx) |
| NL (1) | NL7508301A (xx) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4029681A (en) * | 1976-02-13 | 1977-06-14 | The Upjohn Company | 13,14-Didehydro-PG analogs |
-
1975
- 1975-06-11 GB GB2494075A patent/GB1482047A/en not_active Expired
- 1975-06-11 GB GB4889576A patent/GB1482049A/en not_active Expired
- 1975-06-11 GB GB4889476A patent/GB1482048A/en not_active Expired
- 1975-06-30 CH CH849975A patent/CH619922A5/de not_active IP Right Cessation
- 1975-07-07 DE DE19752530221 patent/DE2530221A1/de not_active Withdrawn
- 1975-07-11 NL NL7508301A patent/NL7508301A/xx not_active Application Discontinuation
- 1975-07-11 FR FR7521890A patent/FR2285385A1/fr active Granted
- 1975-07-11 JP JP8460175A patent/JPS5134146A/ja active Pending
- 1975-12-23 FR FR7539517A patent/FR2285373A1/fr active Granted
- 1975-12-23 FR FR7539516A patent/FR2285364A1/fr active Granted
-
1979
- 1979-03-20 CH CH261379A patent/CH615923A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2285364B1 (xx) | 1980-07-18 |
| CH619922A5 (en) | 1980-10-31 |
| GB1482047A (en) | 1977-08-03 |
| GB1482049A (en) | 1977-08-03 |
| JPS5134146A (ja) | 1976-03-23 |
| DE2530221A1 (de) | 1976-01-29 |
| CH615923A5 (en) | 1980-02-29 |
| FR2285385A1 (fr) | 1976-04-16 |
| NL7508301A (nl) | 1976-01-14 |
| FR2285385B1 (xx) | 1979-03-09 |
| FR2285364A1 (fr) | 1976-04-16 |
| AU8243775A (en) | 1977-01-06 |
| FR2285373B1 (xx) | 1980-07-18 |
| FR2285373A1 (fr) | 1976-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |