GB1480643A - Amidino-phenyl-ureas processes for their preparation and compositions incorporating them - Google Patents
Amidino-phenyl-ureas processes for their preparation and compositions incorporating themInfo
- Publication number
- GB1480643A GB1480643A GB3137074A GB3137074A GB1480643A GB 1480643 A GB1480643 A GB 1480643A GB 3137074 A GB3137074 A GB 3137074A GB 3137074 A GB3137074 A GB 3137074A GB 1480643 A GB1480643 A GB 1480643A
- Authority
- GB
- United Kingdom
- Prior art keywords
- amidino
- phenyl
- urea
- alkyl
- general formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title 1
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- UFFBMTHBGFGIHF-UHFFFAOYSA-N 2,6-dimethylaniline Chemical compound CC1=CC=CC(C)=C1N UFFBMTHBGFGIHF-UHFFFAOYSA-N 0.000 abstract 2
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 2
- FWQUBKZCULDUQS-UHFFFAOYSA-N 2-chloro-n,6-dimethylaniline Chemical compound CNC1=C(C)C=CC=C1Cl FWQUBKZCULDUQS-UHFFFAOYSA-N 0.000 abstract 2
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 abstract 2
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 abstract 2
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- MSXDAEZTXQQLTJ-UHFFFAOYSA-N 1-(2-chloro-6-methylphenyl)-3-(diaminomethylidene)urea Chemical compound CC1=CC=CC(Cl)=C1NC(=O)N=C(N)N MSXDAEZTXQQLTJ-UHFFFAOYSA-N 0.000 abstract 1
- OYWRJJBDWXNKRO-UHFFFAOYSA-N 1-(4-bromo-2-chloro-6-methylphenyl)-3-(diaminomethylidene)urea Chemical compound CC1=CC(Br)=CC(Cl)=C1NC(=O)NC(N)=N OYWRJJBDWXNKRO-UHFFFAOYSA-N 0.000 abstract 1
- FVWJDGCUZMFFES-UHFFFAOYSA-N 1-carbamimidoyl-1-phenylurea Chemical compound NC(=N)N(C(N)=O)C1=CC=CC=C1 FVWJDGCUZMFFES-UHFFFAOYSA-N 0.000 abstract 1
- YQLRKXVEALTVCZ-UHFFFAOYSA-N 2-isocyanato-1,3-dimethylbenzene Chemical compound CC1=CC=CC(C)=C1N=C=O YQLRKXVEALTVCZ-UHFFFAOYSA-N 0.000 abstract 1
- SRLXJSUKDMSPQJ-UHFFFAOYSA-N 3-(diaminomethylidene)-1-(4-methoxy-2,6-dimethylphenyl)-1-methylurea Chemical compound COC1=CC(C)=C(N(C)C(=O)NC(N)=N)C(C)=C1 SRLXJSUKDMSPQJ-UHFFFAOYSA-N 0.000 abstract 1
- XNCOSPRUTUOJCJ-UHFFFAOYSA-N Biguanide Chemical compound NC(N)=NC(N)=N XNCOSPRUTUOJCJ-UHFFFAOYSA-N 0.000 abstract 1
- 229940123208 Biguanide Drugs 0.000 abstract 1
- 206010020601 Hyperchlorhydria Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000007101 Muscle Cramp Diseases 0.000 abstract 1
- 208000005392 Spasm Diseases 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- QSACPWSIIRFHHR-UHFFFAOYSA-N dimethylphenyl isocyanide Natural products CC1=CC=CC(C)=C1C#N QSACPWSIIRFHHR-UHFFFAOYSA-N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- UUEVFMOUBSLVJW-UHFFFAOYSA-N oxo-[[1-[2-[2-[2-[4-(oxoazaniumylmethylidene)pyridin-1-yl]ethoxy]ethoxy]ethyl]pyridin-4-ylidene]methyl]azanium;dibromide Chemical compound [Br-].[Br-].C1=CC(=C[NH+]=O)C=CN1CCOCCOCCN1C=CC(=C[NH+]=O)C=C1 UUEVFMOUBSLVJW-UHFFFAOYSA-N 0.000 abstract 1
- 230000036269 ulceration Effects 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37962773A | 1973-07-16 | 1973-07-16 | |
| US37962673A | 1973-07-16 | 1973-07-16 | |
| US37977373A | 1973-07-16 | 1973-07-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1480643A true GB1480643A (en) | 1977-07-20 |
Family
ID=27409463
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3137074A Expired GB1480643A (en) | 1973-07-16 | 1974-07-16 | Amidino-phenyl-ureas processes for their preparation and compositions incorporating them |
Country Status (2)
| Country | Link |
|---|---|
| FR (1) | FR2237625B1 (enrdf_load_html_response) |
| GB (1) | GB1480643A (enrdf_load_html_response) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0073276A1 (en) * | 1981-08-24 | 1983-03-09 | Rorer International (Overseas) Inc. | A method of increasing the feed efficiency of animals, and compositions for use in such a method |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1194835A (en) * | 1966-07-07 | 1970-06-10 | Wellcome Found | Novel 1-Amidino-3-Phenyl-Urea Derivatives, the preparation thereof and Compositions containing the same |
-
1974
- 1974-07-16 GB GB3137074A patent/GB1480643A/en not_active Expired
- 1974-07-16 FR FR7424763A patent/FR2237625B1/fr not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0073276A1 (en) * | 1981-08-24 | 1983-03-09 | Rorer International (Overseas) Inc. | A method of increasing the feed efficiency of animals, and compositions for use in such a method |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2237625B1 (enrdf_load_html_response) | 1978-07-28 |
| FR2237625A1 (enrdf_load_html_response) | 1975-02-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SU873875A3 (ru) | Способ получени производных о-метилбензанилида | |
| SU648103A3 (ru) | Способ получени тетразол - (1,5-а) хинолинов или их солей | |
| GB1345880A (en) | Pyridazine derivatives | |
| MX9603004A (es) | Guanididas sustituidas del acido cinamico, procedimiento para su preparacion, su empleo como medicamento o agente de diagnostico, asi como medicamento que las contiene. | |
| GB1460980A (en) | 3-substituted diphenylhydantoins | |
| US3594349A (en) | Substituted polymeric as-triazines | |
| GB1480643A (en) | Amidino-phenyl-ureas processes for their preparation and compositions incorporating them | |
| GB1362918A (en) | Thioesters of guanidinoorganic acids and production thereof | |
| GB1398201A (en) | N-sulphenylated carbamidoximes a process for their preparation and their fungicidal and bactericidal use | |
| IE38531L (en) | Production of n-chloroformyl-carbamic acid amides | |
| GB1436307A (en) | Diaromatic o-aminoalkyl-oximes | |
| US3097240A (en) | Novel sulfonyl-ureas | |
| SU441705A1 (ru) | Способ получени -(4-) (2-метокси-5-хлорбензамидо-этил) бензолсульфонил -циклопентилмочевины | |
| GB1435476A (en) | Thiazole derivatives processes for their preparation and compositions incorporating them | |
| EP0110559A1 (en) | Process for the preparation of 4-chloro-2-nitrobenzonitrile | |
| GB1381063A (en) | Process for the manufacture of 2-aryl-v-triazoles | |
| GB1398655A (en) | Process for the production of lactam hydrazones of aromatic systems | |
| US4111989A (en) | N-Substituted alkanesulfenyl-N-alkyl and N-substituted alkanethio-sulfenyl-N-alkyl carbamoyl halide compounds | |
| GB1450801A (en) | Pyridinecarboxamide sulphonylurea hypoglycemic agents | |
| GB1311432A (en) | Guanidine derivatives their preparation and antiviral compositions containing them | |
| GB1259568A (enrdf_load_html_response) | ||
| GB1458130A (en) | N-2,4-dihalo-2-triazin-6-yl-ureas and process for their manufacture | |
| ES444512A1 (es) | Procedimiento para la preparacion de sales de metales alca- linos de las arilenbis-sulfonilureas. | |
| GB1272354A (en) | Hypoglycemic arylsulphonylureas and arylsulphonylsemicarbazides | |
| GB1418854A (en) | Cyclic sulphoximides |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |