GB1478609A - Guanidine derivative - Google Patents
Guanidine derivativeInfo
- Publication number
- GB1478609A GB1478609A GB12724/76A GB1272476A GB1478609A GB 1478609 A GB1478609 A GB 1478609A GB 12724/76 A GB12724/76 A GB 12724/76A GB 1272476 A GB1272476 A GB 1272476A GB 1478609 A GB1478609 A GB 1478609A
- Authority
- GB
- United Kingdom
- Prior art keywords
- salt
- formula
- guanidine derivative
- novel compound
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1478609 Guanidine derivative ARZNEIMITTELWERK DRESDEN VEB 30 March 1976 [1 April 1975] 12724/76 Heading C2C The novel compound of formula and acid addition salts thereof are prepared by reacting 2 - (2<SP>1</SP>,6<SP>1</SP> - dichlorophenylamino)ethylguanidine or a salt thereof with a compound of Formula II or a salt thereof wherein R 1 is imino, R 2 is C 1-3 alkylthio, C 1-3 alkoxy or optionally substituted pyrazolyl or R 1 and R 2 together with the carbon atom to which they are attached represent nitrile. Pharmaceutical compositions in conventional forms and having antihypertensive activity comprise an above novel compound and a solid or liquid diluent or carrier.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DD185126A DD119039A1 (en) | 1975-04-01 | 1975-04-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1478609A true GB1478609A (en) | 1977-07-06 |
Family
ID=5499742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB12724/76A Expired GB1478609A (en) | 1975-04-01 | 1976-03-30 | Guanidine derivative |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS51143629A (en) |
| AT (1) | AT346857B (en) |
| BE (1) | BE840301A (en) |
| BG (1) | BG24463A1 (en) |
| CS (1) | CS186430B1 (en) |
| DD (1) | DD119039A1 (en) |
| DE (1) | DE2612137A1 (en) |
| DK (1) | DK133676A (en) |
| FI (1) | FI760856A (en) |
| FR (1) | FR2305974A1 (en) |
| GB (1) | GB1478609A (en) |
| HU (1) | HU170764B (en) |
| NL (1) | NL7603404A (en) |
| PL (1) | PL100186B1 (en) |
| SE (1) | SE7603853L (en) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1016071A (en) * | 1961-02-15 | 1966-01-05 | Smith Kline French Lab | New guanidine derivatives and process for preparing the same |
-
1975
- 1975-04-01 DD DD185126A patent/DD119039A1/xx unknown
-
1976
- 1976-03-22 DE DE19762612137 patent/DE2612137A1/en active Pending
- 1976-03-23 AT AT212376A patent/AT346857B/en not_active IP Right Cessation
- 1976-03-26 DK DK133676A patent/DK133676A/en unknown
- 1976-03-29 CS CS7600002016A patent/CS186430B1/en unknown
- 1976-03-30 GB GB12724/76A patent/GB1478609A/en not_active Expired
- 1976-03-31 FI FI760856A patent/FI760856A/fi not_active Application Discontinuation
- 1976-03-31 PL PL1976188402A patent/PL100186B1/en unknown
- 1976-03-31 SE SE7603853A patent/SE7603853L/en unknown
- 1976-04-01 JP JP51036691A patent/JPS51143629A/en active Pending
- 1976-04-01 FR FR7609554A patent/FR2305974A1/en active Granted
- 1976-04-01 NL NL7603404A patent/NL7603404A/en not_active Application Discontinuation
- 1976-04-01 BE BE165783A patent/BE840301A/en unknown
- 1976-04-01 BG BG7600032773A patent/BG24463A1/en unknown
- 1976-04-01 HU HU76AE00000464A patent/HU170764B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK133676A (en) | 1976-10-02 |
| AT346857B (en) | 1978-11-27 |
| PL100186B1 (en) | 1978-09-30 |
| NL7603404A (en) | 1976-10-05 |
| DE2612137A1 (en) | 1976-10-14 |
| BG24463A1 (en) | 1978-03-10 |
| SE7603853L (en) | 1976-10-02 |
| ATA212376A (en) | 1978-04-15 |
| BE840301A (en) | 1976-10-01 |
| FI760856A (en) | 1976-10-02 |
| HU170764B (en) | 1977-09-28 |
| CS186430B1 (en) | 1978-12-29 |
| DD119039A1 (en) | 1976-04-05 |
| FR2305974A1 (en) | 1976-10-29 |
| JPS51143629A (en) | 1976-12-10 |
| FR2305974B1 (en) | 1979-01-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |