GB1475891A - Method of preparing dl-or l-tetramisole and acid addition salts thereof - Google Patents
Method of preparing dl-or l-tetramisole and acid addition salts thereofInfo
- Publication number
- GB1475891A GB1475891A GB2270974A GB2270974A GB1475891A GB 1475891 A GB1475891 A GB 1475891A GB 2270974 A GB2270974 A GB 2270974A GB 2270974 A GB2270974 A GB 2270974A GB 1475891 A GB1475891 A GB 1475891A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- acid addition
- phenyl
- iminothiazolidine
- concentrated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 4
- 150000003839 salts Chemical class 0.000 title abstract 4
- HLFSDGLLUJUHTE-SNVBAGLBSA-N Levamisole Chemical compound C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 HLFSDGLLUJUHTE-SNVBAGLBSA-N 0.000 title 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 6
- FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical compound C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 abstract 2
- ZMZDMBWJUHKJPS-UHFFFAOYSA-N thiocyanic acid Chemical compound SC#N ZMZDMBWJUHKJPS-UHFFFAOYSA-N 0.000 abstract 2
- NOWKCMXCCJGMRR-UHFFFAOYSA-N Aziridine Chemical compound C1CN1 NOWKCMXCCJGMRR-UHFFFAOYSA-N 0.000 abstract 1
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 abstract 1
- AWMVMTVKBNGEAK-UHFFFAOYSA-N Styrene oxide Chemical compound C1OC1C1=CC=CC=C1 AWMVMTVKBNGEAK-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 238000007865 diluting Methods 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/18—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
- C07D203/10—Radicals substituted by singly bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37122873A | 1973-06-18 | 1973-06-18 | |
| US371229A US3890341A (en) | 1973-06-18 | 1973-06-18 | Method of preparing di 6-phenyl-2,3,5,6-tetrahydro-imidazo{8 2,1-B{9 thiazole and acid addition salts thereof |
| US43623074A | 1974-01-24 | 1974-01-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1475891A true GB1475891A (en) | 1977-06-10 |
Family
ID=27409005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2270974A Expired GB1475891A (en) | 1973-06-18 | 1974-05-21 | Method of preparing dl-or l-tetramisole and acid addition salts thereof |
Country Status (5)
| Country | Link |
|---|---|
| DE (1) | DE2429227A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2233329B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1475891A (enrdf_load_stackoverflow) |
| IT (1) | IT1047136B (enrdf_load_stackoverflow) |
| NL (1) | NL183942C (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4072687A (en) * | 1975-11-06 | 1978-02-07 | Ajinomoto Co., Inc. | Process for producing 2-amino-(2)-thiazoline-4-carboxylic acid |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU409983B2 (en) * | 1965-07-19 | 1970-12-31 | Imperial Chemical Industries Of Australia New Zealand Limited | Process for the manufacture of thia zolidines and thiazolidines produced thereby |
| GB1076109A (en) * | 1965-10-05 | 1967-07-19 | Americal Cyanamid Company | Substituted 6-phenyl 2,3,5,6-tetrahydroimidazo[2,1-b] thiazoles, salts thereof, novel intermediates thereof, and the preparation of the above compounds |
| BE772646A (fr) * | 1970-09-24 | 1972-03-15 | Ici Ltd | Production du tetramisole |
-
1974
- 1974-05-21 GB GB2270974A patent/GB1475891A/en not_active Expired
- 1974-05-31 NL NL7407407A patent/NL183942C/xx active Search and Examination
- 1974-06-14 IT IT5152474A patent/IT1047136B/it active
- 1974-06-18 FR FR7421167A patent/FR2233329B1/fr not_active Expired
- 1974-06-18 DE DE19742429227 patent/DE2429227A1/de active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| IT1047136B (it) | 1980-09-10 |
| FR2233329A1 (enrdf_load_stackoverflow) | 1975-01-10 |
| NL183942C (nl) | 1989-03-01 |
| NL7407407A (enrdf_load_stackoverflow) | 1974-12-20 |
| DE2429227C2 (enrdf_load_stackoverflow) | 1988-11-03 |
| DE2429227A1 (de) | 1975-01-09 |
| AU6947374A (en) | 1975-12-04 |
| FR2233329B1 (enrdf_load_stackoverflow) | 1978-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19930521 |