GB1473705A - Material separation apparatus - Google Patents

Material separation apparatus

Info

Publication number
GB1473705A
GB1473705A GB2837874A GB2837874A GB1473705A GB 1473705 A GB1473705 A GB 1473705A GB 2837874 A GB2837874 A GB 2837874A GB 2837874 A GB2837874 A GB 2837874A GB 1473705 A GB1473705 A GB 1473705A
Authority
GB
United Kingdom
Prior art keywords
chamber structure
rotor
plasma
separation chamber
separation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2837874A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Instrumentation Laboratory Co
Original Assignee
Instrumentation Laboratory Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instrumentation Laboratory Co filed Critical Instrumentation Laboratory Co
Publication of GB1473705A publication Critical patent/GB1473705A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B1/00—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles
    • B04B1/10—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles with discharging outlets in the plane of the maximum diameter of the bowl
    • B04B1/14—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles with discharging outlets in the plane of the maximum diameter of the bowl with periodical discharge
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/111666—Utilizing a centrifuge or compartmented rotor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Ecology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Centrifugal Separators (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

1473705 Centrifugal separators INSTRUM- ENTATION LABORATORY 26 June 1974 [5 July 1973] 28378/74 Heading B2P [Also in Division G1] A blood analysis system comprises a plasma analysis unit which includes a cuvette 224, a separation apparatus 12 for separating plasma from whole blood, a first conduit 202, 60 for supplying whole blood to the separation apparatus and a second conduit 62, 214, 218, 222 for transferring plasma from the separation apparatus to the analysis cell 224 for analysis. Reagent may be introduced into cell 224 (by means not shown) before the plasma is transferred to the cell and the measurement signal from photosensor 230 may be processed by control system 232 and an output displayed at 236. The separation apparatus in the embodiment shown comprises (Fig. 1) a rotor which may be rotated by permanent split capacitor motor 24 and belt 30, within the rotor separation chamber structure which as shown comprises chambers 122, 124 (or in another embodiment in which the rotor is driven by a flexible shaft, a single chamber), the separation chamber structure being offset from the rotor axis, also within the rotor second chamber structure 120, discharge port structure 104, 106 located adjacent the lower position of the separation chamber structure on the side remote from the rotor axis restriction structure 130 between the separation chamber structure and the second chamber structure, an upper portion of the separation chamber structure being adjacent the restriction structure and a lower portion being spaced further from the rotor axis than the upper portion, the restriction structure being adapted to retain a first portion of the separated material in the separation chamber structure while permitting a second portion (e.g. the plasma) to flow from the separation chamber structure into the second chamber structure, valve structure 110, 158 for normally closing the discharge port structure and second port structure 54 for introducing material into and removing material from the second chamber structure. The valve structures each comprise a seal disc (154) of resilient material pressed in the closed position of the valve against an open end of the discharge port by a glass actuating sphere (158) by means of a flat on a cylindrical glass filled nylon pin 110, both nylon pins being engaged by a steel actuator disc 170 for vertical movement by actuator 182 to move the valves between their open and closed positions.
GB2837874A 1973-07-05 1974-06-26 Material separation apparatus Expired GB1473705A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US376719A US3880592A (en) 1973-07-05 1973-07-05 Blood analysis system including a plasma separator

Publications (1)

Publication Number Publication Date
GB1473705A true GB1473705A (en) 1977-05-18

Family

ID=23486186

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2837874A Expired GB1473705A (en) 1973-07-05 1974-06-26 Material separation apparatus

Country Status (7)

Country Link
US (1) US3880592A (en)
JP (2) JPS534949B2 (en)
CA (1) CA1012942A (en)
DE (1) DE2432498C3 (en)
FR (1) FR2236179B1 (en)
GB (1) GB1473705A (en)
IT (1) IT1020659B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2141051A (en) * 1983-06-06 1984-12-12 Seiko Instr & Electronics Centrifugal separator device

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU171920B (en) * 1975-12-30 1978-04-28 Mueszeripari Muevek Lab Device for blood-typing
US4015774A (en) * 1976-06-07 1977-04-05 Minneapolis War Memorial Blood Bank Dual centrifuge and sample container
NL7613690A (en) * 1976-12-09 1978-06-13 Cenco Instr Bv CYTOCENTRIFUGE.
US4274885A (en) * 1979-07-19 1981-06-23 Swartout Bobbye J Method for washing centrifugal analyzer test disks
US4409820A (en) * 1981-06-17 1983-10-18 Irwin Nash Apparatus and method for use in quantitative analysis of a fluid suspension
JPS5817514U (en) * 1981-07-29 1983-02-03 日野自動車株式会社 Instrument lighting system
DE3616062A1 (en) * 1986-05-13 1987-11-19 Fresenius Ag METHOD FOR DETERMINING GAS PARTIAL PRESSURES IN BLOOD AND DEVICE FOR IMPLEMENTING THE METHOD
US4933291A (en) * 1986-12-22 1990-06-12 Eastman Kodak Company Centrifugable pipette tip and pipette therefor
WO1999014593A1 (en) * 1997-09-16 1999-03-25 Sekisui Chemical Co., Ltd. Blood test container and blood test method
US6248542B1 (en) * 1997-12-09 2001-06-19 Massachusetts Institute Of Technology Optoelectronic sensor
JP3847053B2 (en) * 2000-03-15 2006-11-15 純 菊地 Blood analyzer
EP1458488B1 (en) 2000-11-02 2011-12-21 CaridianBCT, Inc. Fluid separation devices, systems and methods
US7214346B2 (en) 2001-02-07 2007-05-08 Massachusetts Institute Of Technology Optoelectronic detection system
US7422860B2 (en) 2001-02-07 2008-09-09 Massachusetts Institute Of Technology Optoelectronic detection system
US8216797B2 (en) 2001-02-07 2012-07-10 Massachusetts Institute Of Technology Pathogen detection biosensor
US7182866B2 (en) * 2004-03-31 2007-02-27 Dirk Blaine Forman Apparatus and method for separating impurities from a stream
US7850917B2 (en) * 2008-03-11 2010-12-14 Ortho-Clinical Diagnostics, Inc. Particle agglutination in a tip
US10596570B2 (en) * 2014-05-16 2020-03-24 Qvella Corporation Apparatus, system and method for performing automated centrifugal separation

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE110576C (en) *
US1101549A (en) * 1911-10-24 1914-06-30 Balthasar Hoffman Centrifugal separating-machine.
US2291117A (en) * 1939-12-29 1942-07-28 Laval Separator Co De Centrifugal separator
US2883103A (en) * 1953-03-09 1959-04-21 Technicon International Ltd Centrifuge apparatus and method
US2834541A (en) * 1956-09-20 1958-05-13 Sorvall Inc Ivan Centrifuging apparatus and system
FR1260968A (en) * 1959-06-24 1961-05-12 Becton Dickinson Co Container for blood, and method and machine for separating precipitates from the liquid constituents of blood
US3096283A (en) * 1959-06-24 1963-07-02 Becton Dickinson Co Container for blood and machine for separating precipitates from liquid blood constituents
FR1360423A (en) * 1959-06-24 1964-05-08 Centrifugation apparatus and method
US3211530A (en) * 1962-04-10 1965-10-12 Technicon Instr Centrifugal separator and analyzing means
US3291387A (en) * 1964-01-16 1966-12-13 Technicon Instr Continuous centrifugal separator
JPS4915339Y1 (en) * 1968-10-03 1974-04-17
GB1337424A (en) * 1970-10-08 1973-11-14 Rohe Scientific Corp Automated centrifuging apparatus

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2141051A (en) * 1983-06-06 1984-12-12 Seiko Instr & Electronics Centrifugal separator device

Also Published As

Publication number Publication date
FR2236179A1 (en) 1975-01-31
FR2236179B1 (en) 1978-01-13
JPS5038167A (en) 1975-04-09
JPS534949B2 (en) 1978-02-22
CA1012942A (en) 1977-06-28
DE2432498C3 (en) 1981-10-22
JPS5224262B2 (en) 1977-06-30
JPS515665A (en) 1976-01-17
IT1020659B (en) 1977-12-30
US3880592A (en) 1975-04-29
DE2432498A1 (en) 1975-01-30
DE2432498B2 (en) 1981-03-12

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee