GB1471399A - Sulphonamides - Google Patents
SulphonamidesInfo
- Publication number
- GB1471399A GB1471399A GB2594275A GB2594275A GB1471399A GB 1471399 A GB1471399 A GB 1471399A GB 2594275 A GB2594275 A GB 2594275A GB 2594275 A GB2594275 A GB 2594275A GB 1471399 A GB1471399 A GB 1471399A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cyclopropyl
- cyclohexyl
- group
- dihydrocytosine
- cyanoethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003456 sulfonamides Chemical class 0.000 title 1
- -1 sulphanilamide alkali metal salts Chemical class 0.000 abstract 5
- 125000006701 (C1-C7) alkyl group Chemical group 0.000 abstract 3
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 1
- UJAAQJZEVGWFCM-UHFFFAOYSA-N 1-(2-cyanoethyl)-1-(cyclopropylmethyl)urea Chemical compound N#CCCN(C(=O)N)CC1CC1 UJAAQJZEVGWFCM-UHFFFAOYSA-N 0.000 abstract 1
- WZIDXHYJYCPRGU-UHFFFAOYSA-N 1-(2-cyanoethyl)-1-cyclopentylurea Chemical compound N#CCCN(C(=O)N)C1CCCC1 WZIDXHYJYCPRGU-UHFFFAOYSA-N 0.000 abstract 1
- SKGBDXKGMAITTB-UHFFFAOYSA-N 1-ethyl-5-methyl-4-sulfanylidenepyrimidin-2-one Chemical compound CCN1C=C(C)C(=S)NC1=O SKGBDXKGMAITTB-UHFFFAOYSA-N 0.000 abstract 1
- QGKGASXQTBQINX-UHFFFAOYSA-N 3,4-dihydro-1h-pyrimidin-2-one Chemical group O=C1NCC=CN1 QGKGASXQTBQINX-UHFFFAOYSA-N 0.000 abstract 1
- YHGZCPAPXDXHCY-UHFFFAOYSA-N 3-(cyclopentylamino)propanenitrile Chemical compound N#CCCNC1CCCC1 YHGZCPAPXDXHCY-UHFFFAOYSA-N 0.000 abstract 1
- TXBNHIOKNSJQMO-UHFFFAOYSA-N 3-(cyclopropylmethylamino)propanenitrile Chemical compound N#CCCNCC1CC1 TXBNHIOKNSJQMO-UHFFFAOYSA-N 0.000 abstract 1
- SDPKJYGDPREKJW-UHFFFAOYSA-N 4-amino-1-(cyclopropylmethyl)pyrimidin-2-one Chemical compound O=C1N=C(N)C=CN1CC1CC1 SDPKJYGDPREKJW-UHFFFAOYSA-N 0.000 abstract 1
- TWZFIOJEBDZSAQ-UHFFFAOYSA-N 4-amino-1-cyclohexylpyrimidin-2-one Chemical compound O=C1N=C(N)C=CN1C1CCCCC1 TWZFIOJEBDZSAQ-UHFFFAOYSA-N 0.000 abstract 1
- DXFLKFBBEGOBFE-UHFFFAOYSA-N 4-amino-1-cyclopentylpyrimidin-2-one Chemical compound O=C1N=C(N)C=CN1C1CCCC1 DXFLKFBBEGOBFE-UHFFFAOYSA-N 0.000 abstract 1
- GGBCQYHNNBOTGS-UHFFFAOYSA-N 4-amino-1-cyclopropylpyrimidin-2-one Chemical compound O=C1N=C(N)C=CN1C1CC1 GGBCQYHNNBOTGS-UHFFFAOYSA-N 0.000 abstract 1
- MOIXWKHGGNWSRZ-UHFFFAOYSA-N 4-amino-N-(2H-pyrimidin-1-yl)benzenesulfonamide Chemical class S(=O)(C1=CC=C(C=C1)N)(=O)NN1CN=CC=C1 MOIXWKHGGNWSRZ-UHFFFAOYSA-N 0.000 abstract 1
- FXSQLUATVCBTIM-UHFFFAOYSA-N 5-(cyclohexylmethyl)-4-sulfanylidene-1H-pyrimidin-2-one Chemical class C1(CCCCC1)CC=1C(NC(NC=1)=O)=S FXSQLUATVCBTIM-UHFFFAOYSA-N 0.000 abstract 1
- HSHFQPHGGINVQC-UHFFFAOYSA-N 6-(cyclohexylamino)-5-methyl-1H-pyrimidin-2-one Chemical class C1(CCCCC1)NC1=NC(NC=C1C)=O HSHFQPHGGINVQC-UHFFFAOYSA-N 0.000 abstract 1
- HCRHTGNBOHNVDE-UHFFFAOYSA-N 6-amino-3-(cyclopropylmethyl)-4,5-dihydropyrimidin-2-one Chemical compound C1CC(N)=NC(=O)N1CC1CC1 HCRHTGNBOHNVDE-UHFFFAOYSA-N 0.000 abstract 1
- DEFJDLZWCNNPCA-UHFFFAOYSA-N 6-amino-5-bromo-3-(cyclopropylmethyl)-4,5-dihydropyrimidin-2-one Chemical compound C1C(Br)C(N)=NC(=O)N1CC1CC1 DEFJDLZWCNNPCA-UHFFFAOYSA-N 0.000 abstract 1
- SSSDWZFUOHOUAC-UHFFFAOYSA-N 6-amino-5-bromo-3-cyclopentyl-4,5-dihydropyrimidin-2-one Chemical compound C1C(Br)C(N)=NC(=O)N1C1CCCC1 SSSDWZFUOHOUAC-UHFFFAOYSA-N 0.000 abstract 1
- 101000653791 Bos taurus Protein S100-A12 Proteins 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 150000002828 nitro derivatives Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 229940124530 sulfonamide Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/18—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/26—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/56—One oxygen atom and one sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/69—Benzenesulfonamido-pyrimidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US480784A US3923792A (en) | 1974-06-19 | 1974-06-19 | Sulfacytosine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1471399A true GB1471399A (en) | 1977-04-27 |
Family
ID=23909351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2594275A Expired GB1471399A (en) | 1974-06-19 | 1975-06-18 | Sulphonamides |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US3923792A (enExample) |
| JP (1) | JPS5113781A (enExample) |
| AU (1) | AU8222075A (enExample) |
| BE (1) | BE830360A (enExample) |
| DD (1) | DD118090A5 (enExample) |
| DE (1) | DE2526795A1 (enExample) |
| DK (1) | DK274575A (enExample) |
| ES (1) | ES438661A1 (enExample) |
| FI (1) | FI751786A7 (enExample) |
| FR (1) | FR2275218A1 (enExample) |
| GB (1) | GB1471399A (enExample) |
| HU (1) | HU170013B (enExample) |
| IE (1) | IE41563B1 (enExample) |
| IL (1) | IL47500A0 (enExample) |
| LU (1) | LU72748A1 (enExample) |
| NL (1) | NL7507154A (enExample) |
| NO (1) | NO752174L (enExample) |
| PL (1) | PL95005B1 (enExample) |
| SE (1) | SE7506907L (enExample) |
| ZA (1) | ZA752558B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54106635A (en) * | 1978-01-30 | 1979-08-21 | Mo Tekusuchiruni I | Apparatus for separating fiber and supplying said fiber into spinning chamber |
| IL92096A0 (en) | 1988-10-25 | 1990-07-12 | Abbott Lab | Carboxylic nucleoside analogs |
| US5153352A (en) * | 1988-10-25 | 1992-10-06 | Bristol-Myers Squibb Company | Process for preparation of intermediates of carbocyclic nucleoside analogs |
| US5246931A (en) * | 1988-10-25 | 1993-09-21 | Bristol-Myers Squibb Company | Carbocyclic nucleoside analogs |
| US4988703A (en) * | 1989-05-22 | 1991-01-29 | Abbott Laboratories | Carbocyclic nucleoside analogs with antiviral activity |
| DE69230349T2 (de) * | 1991-03-05 | 2000-07-27 | Ajinomoto Co., Inc. | Cyclopropanderivat |
| US7973060B2 (en) * | 2005-10-13 | 2011-07-05 | Crystalgenomics, Inc. | Fab I inhibitor and process for preparing same |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3422098A (en) * | 1962-12-14 | 1969-01-14 | Ciba Geigy Corp | Sulfanilamido-pyrimidines |
| US3457278A (en) * | 1964-10-15 | 1969-07-22 | Geigy Chem Corp | Cyclopropyl-4-sulfanilamido-pyrimidines |
| US3375247A (en) * | 1965-08-02 | 1968-03-26 | Parke Davis & Co | Heterocyclic compounds and methods for their production |
-
1974
- 1974-06-19 US US480784A patent/US3923792A/en not_active Expired - Lifetime
-
1975
- 1975-04-21 ZA ZA00752558A patent/ZA752558B/xx unknown
- 1975-06-16 DE DE19752526795 patent/DE2526795A1/de active Pending
- 1975-06-16 SE SE7506907A patent/SE7506907L/xx unknown
- 1975-06-16 NL NL7507154A patent/NL7507154A/xx unknown
- 1975-06-16 FI FI751786A patent/FI751786A7/fi not_active Application Discontinuation
- 1975-06-17 DD DD186692A patent/DD118090A5/xx unknown
- 1975-06-17 IL IL47500A patent/IL47500A0/xx unknown
- 1975-06-17 JP JP50072813A patent/JPS5113781A/ja active Pending
- 1975-06-17 FR FR7518866A patent/FR2275218A1/fr not_active Withdrawn
- 1975-06-17 LU LU72748A patent/LU72748A1/xx unknown
- 1975-06-18 HU HUHO1807A patent/HU170013B/hu unknown
- 1975-06-18 ES ES438661A patent/ES438661A1/es not_active Expired
- 1975-06-18 IE IE1365/75A patent/IE41563B1/en unknown
- 1975-06-18 AU AU82220/75A patent/AU8222075A/en not_active Expired
- 1975-06-18 GB GB2594275A patent/GB1471399A/en not_active Expired
- 1975-06-18 NO NO752174A patent/NO752174L/no unknown
- 1975-06-18 PL PL1975181325A patent/PL95005B1/pl unknown
- 1975-06-18 DK DK274575A patent/DK274575A/da unknown
- 1975-06-18 BE BE157434A patent/BE830360A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2275218A1 (fr) | 1976-01-16 |
| ZA752558B (en) | 1976-03-31 |
| DE2526795A1 (de) | 1976-01-08 |
| LU72748A1 (enExample) | 1976-11-11 |
| IE41563L (en) | 1975-12-19 |
| SE7506907L (sv) | 1975-12-22 |
| ES438661A1 (es) | 1977-03-01 |
| BE830360A (fr) | 1975-12-18 |
| US3923792A (en) | 1975-12-02 |
| IE41563B1 (en) | 1980-01-30 |
| DK274575A (da) | 1975-12-20 |
| PL95005B1 (enExample) | 1977-09-30 |
| JPS5113781A (enExample) | 1976-02-03 |
| AU8222075A (en) | 1976-12-23 |
| NL7507154A (nl) | 1975-12-23 |
| IL47500A0 (en) | 1975-08-31 |
| DD118090A5 (enExample) | 1976-02-12 |
| NO752174L (enExample) | 1975-12-22 |
| HU170013B (enExample) | 1977-03-28 |
| FI751786A7 (enExample) | 1975-12-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |