GB1471276A - 5-benzylpicolinic acid deri vatives - Google Patents
5-benzylpicolinic acid deri vativesInfo
- Publication number
- GB1471276A GB1471276A GB96376A GB96376A GB1471276A GB 1471276 A GB1471276 A GB 1471276A GB 96376 A GB96376 A GB 96376A GB 96376 A GB96376 A GB 96376A GB 1471276 A GB1471276 A GB 1471276A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkoxy
- acid
- hydroxy
- compounds
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- MSNWMTGDQGJSNP-UHFFFAOYSA-N 5-benzylpyridine-2-carboxylic acid Chemical compound C1=NC(C(=O)O)=CC=C1CC1=CC=CC=C1 MSNWMTGDQGJSNP-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000003545 alkoxy group Chemical group 0.000 abstract 5
- 239000002253 acid Substances 0.000 abstract 4
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 230000001590 oxidative effect Effects 0.000 abstract 2
- JPJALAQPGMAKDF-UHFFFAOYSA-N selenium dioxide Chemical compound O=[Se]=O JPJALAQPGMAKDF-UHFFFAOYSA-N 0.000 abstract 2
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 1
- 125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000003840 hydrochlorides Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- -1 nitro, amino, acetylamino, hydroxy Chemical group 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 150000004965 peroxy acids Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1000375A JPS5186472A (en) | 1975-01-22 | 1975-01-22 | 55 benjirupikorinsanjudotaino seiho |
| JP1000275A JPS5186471A (en) | 1975-01-22 | 1975-01-22 | 55 benjirupikorinsanjudotaino seiho |
| JP1000075A JPS5186467A (en) | 1975-01-22 | 1975-01-22 | 55 benjirupikorinsanjudotaino seiho |
| JP1000175A JPS5186470A (en) | 1975-01-22 | 1975-01-22 | 55 benjirupikorinsanjudotaino seiho |
| JP999875A JPS5186468A (en) | 1975-01-22 | 1975-01-22 | 55 benjirupikorinsanjudotainoseiho |
| JP999975A JPS5186469A (en) | 1975-01-22 | 1975-01-22 | 55 benjirupikorinsanjudotaino seiho |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1471276A true GB1471276A (en) | 1977-04-21 |
Family
ID=27548239
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB96376A Expired GB1471276A (en) | 1975-01-22 | 1976-01-12 | 5-benzylpicolinic acid deri vatives |
Country Status (3)
| Country | Link |
|---|---|
| DE (1) | DE2602340C3 (enrdf_load_stackoverflow) |
| FR (1) | FR2298331A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1471276A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4271170A (en) | 1978-12-28 | 1981-06-02 | Ono Pharmaceutical Co., Ltd., | Pyridine derivatives |
| EP1132376A4 (en) * | 1998-11-20 | 2002-09-18 | Takeda Chemical Industries Ltd | BETA-AMYLOID PROTEIN PRODUCTION / SECRETION INHIBITORS |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008525363A (ja) | 2004-12-23 | 2008-07-17 | グラクソ グループ リミテッド | プロスタグランジン媒介疾患治療のためのピリジン化合物 |
-
1976
- 1976-01-12 GB GB96376A patent/GB1471276A/en not_active Expired
- 1976-01-21 FR FR7601613A patent/FR2298331A1/fr active Granted
- 1976-01-22 DE DE19762602340 patent/DE2602340C3/de not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4271170A (en) | 1978-12-28 | 1981-06-02 | Ono Pharmaceutical Co., Ltd., | Pyridine derivatives |
| EP1132376A4 (en) * | 1998-11-20 | 2002-09-18 | Takeda Chemical Industries Ltd | BETA-AMYLOID PROTEIN PRODUCTION / SECRETION INHIBITORS |
| US6586475B1 (en) | 1998-11-20 | 2003-07-01 | Takeda Chemical Industries, Ltd. | β-amyloid protein production/secretion inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2602340B2 (de) | 1977-12-29 |
| DE2602340A1 (de) | 1976-07-29 |
| FR2298331A1 (fr) | 1976-08-20 |
| DE2602340C3 (de) | 1978-08-31 |
| FR2298331B1 (enrdf_load_stackoverflow) | 1979-09-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |