GB1467528A - Piperazinium 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolyl acetate - Google Patents
Piperazinium 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolyl acetateInfo
- Publication number
- GB1467528A GB1467528A GB682775A GB682775A GB1467528A GB 1467528 A GB1467528 A GB 1467528A GB 682775 A GB682775 A GB 682775A GB 682775 A GB682775 A GB 682775A GB 1467528 A GB1467528 A GB 1467528A
- Authority
- GB
- United Kingdom
- Prior art keywords
- piperazinium
- chlorobenzoyl
- methoxy
- methyl
- indomethacin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 Piperazinium 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolyl acetate Chemical compound 0.000 title 1
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 241001620634 Roger Species 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 229960000905 indomethacin Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES423834A ES423834A1 (es) | 1974-03-02 | 1974-03-02 | Procedimiento de obtencion de una nueva sal de piperacina del acido (1 - p - clorobenzoil - 2 - metil - 5 - metoxi - 3- indolil) acetico. |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1467528A true GB1467528A (en) | 1977-03-16 |
Family
ID=8466108
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB682775A Expired GB1467528A (en) | 1974-03-02 | 1975-02-18 | Piperazinium 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolyl acetate |
Country Status (4)
Country | Link |
---|---|
BE (1) | BE826038A (enrdf_load_stackoverflow) |
ES (1) | ES423834A1 (enrdf_load_stackoverflow) |
FR (1) | FR2262522B1 (enrdf_load_stackoverflow) |
GB (1) | GB1467528A (enrdf_load_stackoverflow) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4551475A (en) * | 1981-02-24 | 1985-11-05 | Ciba-Geigy Corporation | Pharmaceutical preparations for topical application which contain salts of alkanecarboxylic acids |
RU2144534C1 (ru) * | 1997-06-30 | 2000-01-20 | Николай Иванович Трубчанин | Способ получения морфолиния 3-метил-1,2,4-триазолил-5-тиоацетата, проявляющего гепатозащитную, ранозаживляющую и противовирусную активность |
EP1893190A4 (en) * | 2005-04-28 | 2010-07-28 | Theraquest Biosciences Llc | METHODS AND COMPOSITIONS FOR TREATING PAIN |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61152656A (ja) * | 1984-12-27 | 1986-07-11 | Taiho Yakuhin Kogyo Kk | ピペラジン誘導体 |
-
1974
- 1974-03-02 ES ES423834A patent/ES423834A1/es not_active Expired
-
1975
- 1975-02-18 GB GB682775A patent/GB1467528A/en not_active Expired
- 1975-02-27 BE BE2054178A patent/BE826038A/xx unknown
- 1975-02-28 FR FR7507103A patent/FR2262522B1/fr not_active Expired
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4551475A (en) * | 1981-02-24 | 1985-11-05 | Ciba-Geigy Corporation | Pharmaceutical preparations for topical application which contain salts of alkanecarboxylic acids |
RU2144534C1 (ru) * | 1997-06-30 | 2000-01-20 | Николай Иванович Трубчанин | Способ получения морфолиния 3-метил-1,2,4-триазолил-5-тиоацетата, проявляющего гепатозащитную, ранозаживляющую и противовирусную активность |
EP1893190A4 (en) * | 2005-04-28 | 2010-07-28 | Theraquest Biosciences Llc | METHODS AND COMPOSITIONS FOR TREATING PAIN |
Also Published As
Publication number | Publication date |
---|---|
BE826038A (fr) | 1975-06-16 |
ES423834A1 (es) | 1976-06-01 |
FR2262522A1 (enrdf_load_stackoverflow) | 1975-09-26 |
FR2262522B1 (enrdf_load_stackoverflow) | 1980-02-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |