GB1465405A - 1,2,4-benzotriazine derivatives - Google Patents

1,2,4-benzotriazine derivatives

Info

Publication number
GB1465405A
GB1465405A GB486274A GB486274A GB1465405A GB 1465405 A GB1465405 A GB 1465405A GB 486274 A GB486274 A GB 486274A GB 486274 A GB486274 A GB 486274A GB 1465405 A GB1465405 A GB 1465405A
Authority
GB
United Kingdom
Prior art keywords
optionally substituted
feb
heterocyclic
alkoxy
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB486274A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH155573A external-priority patent/CH576231A5/de
Priority claimed from CH1273373A external-priority patent/CH576459A5/de
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of GB1465405A publication Critical patent/GB1465405A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
    • C07D253/10—Condensed 1,2,4-triazines; Hydrogenated condensed 1,2,4-triazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Food Science & Technology (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Animal Husbandry (AREA)
  • Agronomy & Crop Science (AREA)
  • Health & Medical Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)
  • Paints Or Removers (AREA)
  • Fodder In General (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
GB486274A 1973-02-02 1974-02-01 1,2,4-benzotriazine derivatives Expired GB1465405A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH155573A CH576231A5 (en) 1973-02-02 1973-02-02 1,2,4,-benztriazine-1,4-di-N-oxide derivs. - used in veterinary medicine against pathogenic micro-organisms or to promote growth
CH1273373A CH576459A5 (en) 1973-09-05 1973-09-05 1,2,4,-benztriazine-1,4-di-N-oxide derivs. - used in veterinary medicine against pathogenic micro-organisms or to promote growth

Publications (1)

Publication Number Publication Date
GB1465405A true GB1465405A (en) 1977-02-23

Family

ID=25687988

Family Applications (1)

Application Number Title Priority Date Filing Date
GB486274A Expired GB1465405A (en) 1973-02-02 1974-02-01 1,2,4-benzotriazine derivatives

Country Status (12)

Country Link
US (1) US4160833A (enExample)
JP (1) JPS49124235A (enExample)
AR (1) AR207145A1 (enExample)
BE (1) BE810511A (enExample)
CA (1) CA1049014A (enExample)
DE (1) DE2404375A1 (enExample)
FR (1) FR2215967B1 (enExample)
GB (1) GB1465405A (enExample)
IE (1) IE38778B1 (enExample)
IL (1) IL44058A (enExample)
NL (1) NL7401370A (enExample)
SU (1) SU589914A3 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2538179C2 (de) * 1975-08-27 1986-05-28 Bayer Ag, 5090 Leverkusen 3-Alkoxy-benzo-1,2,4-triazine, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Fungizide
NL7801827A (nl) * 1977-02-22 1978-08-24 Ciba Geigy Nieuwe heterocyclische verbindingen.
DE2802488A1 (de) * 1978-01-20 1979-07-26 Bayer Ag 3-azolyl-benzotriazine und -benzotriazin-1-oxide, verfahren zu ihrer herstellung, sowie ihre verwendung zur bekaempfung von pflanzenkrankheiten
NZ194612A (en) * 1979-08-31 1982-12-21 Ici Australia Ltd Benzotriazine derivatives intermediates and herbicidal compositions
GB2203151B (en) * 1986-09-25 1991-05-29 Stanford Res Inst Int 1,2,4-benzotriazine oxides as radiosensitisers and selective cytotoxic agents
US5175287A (en) * 1986-09-25 1992-12-29 S R I International Process for preparing 1,2,4-benzotriazine oxides
US5616584A (en) 1986-09-25 1997-04-01 Sri International 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents
IE62911B1 (en) * 1988-03-18 1995-03-08 Stanford Res Inst Int 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents
GR1000941B (el) * 1989-03-17 1993-03-16 Stanford Res Inst Int Μεθοδος παρασκευης οξειδιων 1,2,4,βενζοτριαζινης.
HU221201B1 (en) 1989-09-18 2002-08-28 Stanford Res Inst Int Process for producing 1,2,4-benzotriazin-oxide derivatives applicable as radiation sensitizer and selective cytotoxic agent, and pharmaceutical compositions containing them
DE19651415A1 (de) * 1996-12-11 1998-06-18 Henkel Ecolab Gmbh & Co Ohg Verfahren zur Instrumentendesinfektion
US20030171411A1 (en) * 2001-12-21 2003-09-11 Kodra Janos Tibor Amide derivatives as therapeutic agents
EP1531815B1 (en) 2002-06-27 2014-09-24 Novo Nordisk A/S Glucokinase activators
US20050282814A1 (en) * 2002-10-03 2005-12-22 Targegen, Inc. Vasculostatic agents and methods of use thereof
DK1723128T3 (da) 2004-01-06 2013-02-18 Novo Nordisk As Heteroarylurinstoffer og deres anvendelse som glucokinaseaktivatorer
NZ551027A (en) * 2004-04-08 2011-01-28 Targegen Inc Benzotriazine inhibitors of kinases
MX2007002208A (es) 2004-08-25 2007-05-08 Targegen Inc Compuestos hetrociclicos y metodos de uso.
CA2611720A1 (en) * 2005-06-08 2006-12-14 Targegen, Inc. Methods and compositions for the treatment of ocular disorders
ATE547396T1 (de) 2005-07-08 2012-03-15 Novo Nordisk As Dicycloalkylcarbamoyl-harnstoffe als glucokinase- aktivatoren
RU2443691C2 (ru) 2005-07-14 2012-02-27 Транстех Фарма, Инк. Мочевинные активаторы глюкокиназы
US8604042B2 (en) * 2005-11-01 2013-12-10 Targegen, Inc. Bi-aryl meta-pyrimidine inhibitors of kinases
MX362412B (es) * 2005-11-01 2019-01-15 Targegen Inc Inhibidores de biaril meta-pirimidina de cinasas.
US8133900B2 (en) * 2005-11-01 2012-03-13 Targegen, Inc. Use of bi-aryl meta-pyrimidine inhibitors of kinases
JP2010515701A (ja) 2007-01-09 2010-05-13 ノボ・ノルデイスク・エー／エス ウレアグルコキナーゼアクチベーター
EP2099777B1 (en) 2007-01-11 2015-08-12 Novo Nordisk A/S Urea glucokinase activators
WO2012060847A1 (en) 2010-11-07 2012-05-10 Targegen, Inc. Compositions and methods for treating myelofibrosis
CN104105692B (zh) * 2011-12-07 2016-06-29 思研（Sri）国际顾问与咨询公司 作为结核分枝杆菌靶向药物的苯并三嗪氧化物
WO2019241089A1 (en) 2018-06-12 2019-12-19 Vtv Therapeutics Llc Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs
WO2021167840A1 (en) 2020-02-18 2021-08-26 Vtv Therapeutics Llc Sulfoxide and sulfone glucokinase activators and methods of use thereof
CN115894385B (zh) * 2023-01-09 2025-02-07 中国科学院长春应用化学研究所 替拉扎明衍生物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3957779A (en) * 1972-11-15 1976-05-18 Bayer Aktiengesellschaft Benzo-1,2,4-triazines
US3991189A (en) * 1972-11-15 1976-11-09 Bayer Aktiengesellschaft Microbiocidal methods and compositions using substituted 1,2,4-triazine-1,4-di-N-oxide derivatives
SE7501624L (enExample) * 1974-03-15 1975-09-16 Ciba Geigy Ag

Also Published As

Publication number Publication date
NL7401370A (enExample) 1974-08-06
FR2215967A1 (enExample) 1974-08-30
CA1049014A (en) 1979-02-20
IL44058A0 (en) 1974-05-16
SU589914A3 (ru) 1978-01-25
FR2215967B1 (enExample) 1977-01-28
DE2404375A1 (de) 1974-08-08
JPS49124235A (enExample) 1974-11-28
US4160833A (en) 1979-07-10
AU6485674A (en) 1975-07-24
IE38778L (en) 1974-08-02
BE810511A (fr) 1974-08-01
AR207145A1 (es) 1976-09-15
IL44058A (en) 1978-10-31
IE38778B1 (en) 1978-05-24

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
48S Specification amended (sect. 8/1949)
SP Amendment (slips) printed
PCNP Patent ceased through non-payment of renewal fee