GB1465405A - 1,2,4-benzotriazine derivatives - Google Patents

1,2,4-benzotriazine derivatives

Info

Publication number
GB1465405A
GB1465405A GB486274A GB486274A GB1465405A GB 1465405 A GB1465405 A GB 1465405A GB 486274 A GB486274 A GB 486274A GB 486274 A GB486274 A GB 486274A GB 1465405 A GB1465405 A GB 1465405A
Authority
GB
United Kingdom
Prior art keywords
optionally substituted
feb
heterocyclic
alkoxy
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB486274A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH155573A external-priority patent/CH576231A5/de
Priority claimed from CH1273373A external-priority patent/CH576459A5/de
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of GB1465405A publication Critical patent/GB1465405A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
    • C07D253/10—Condensed 1,2,4-triazines; Hydrogenated condensed 1,2,4-triazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Food Science & Technology (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Animal Husbandry (AREA)
  • Agronomy & Crop Science (AREA)
  • Health & Medical Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Detergent Compositions (AREA)
  • Paints Or Removers (AREA)
  • Fodder In General (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Cosmetics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
GB486274A 1973-02-02 1974-02-01 1,2,4-benzotriazine derivatives Expired GB1465405A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH155573A CH576231A5 (en) 1973-02-02 1973-02-02 1,2,4,-benztriazine-1,4-di-N-oxide derivs. - used in veterinary medicine against pathogenic micro-organisms or to promote growth
CH1273373A CH576459A5 (en) 1973-09-05 1973-09-05 1,2,4,-benztriazine-1,4-di-N-oxide derivs. - used in veterinary medicine against pathogenic micro-organisms or to promote growth

Publications (1)

Publication Number Publication Date
GB1465405A true GB1465405A (en) 1977-02-23

Family

ID=25687988

Family Applications (1)

Application Number Title Priority Date Filing Date
GB486274A Expired GB1465405A (en) 1973-02-02 1974-02-01 1,2,4-benzotriazine derivatives

Country Status (12)

Country Link
US (1) US4160833A (enExample)
JP (1) JPS49124235A (enExample)
AR (1) AR207145A1 (enExample)
BE (1) BE810511A (enExample)
CA (1) CA1049014A (enExample)
DE (1) DE2404375A1 (enExample)
FR (1) FR2215967B1 (enExample)
GB (1) GB1465405A (enExample)
IE (1) IE38778B1 (enExample)
IL (1) IL44058A (enExample)
NL (1) NL7401370A (enExample)
SU (1) SU589914A3 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2538179C2 (de) * 1975-08-27 1986-05-28 Bayer Ag, 5090 Leverkusen 3-Alkoxy-benzo-1,2,4-triazine, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Fungizide
NL7801827A (nl) * 1977-02-22 1978-08-24 Ciba Geigy Nieuwe heterocyclische verbindingen.
DE2802488A1 (de) * 1978-01-20 1979-07-26 Bayer Ag 3-azolyl-benzotriazine und -benzotriazin-1-oxide, verfahren zu ihrer herstellung, sowie ihre verwendung zur bekaempfung von pflanzenkrankheiten
NZ194612A (en) * 1979-08-31 1982-12-21 Ici Australia Ltd Benzotriazine derivatives intermediates and herbicidal compositions
US5175287A (en) * 1986-09-25 1992-12-29 S R I International Process for preparing 1,2,4-benzotriazine oxides
US5616584A (en) 1986-09-25 1997-04-01 Sri International 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents
DE3790581B4 (de) * 1986-09-25 2004-12-23 Sri International, Menlo Park Verfahren zur selektiven Vernichtung von hypoxischen Tumorzellen
IE62911B1 (en) * 1988-03-18 1995-03-08 Stanford Res Inst Int 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents
GR1000941B (el) * 1989-03-17 1993-03-16 Stanford Res Inst Int Μεθοδος παρασκευης οξειδιων 1,2,4,βενζοτριαζινης.
EP0478545B1 (en) * 1989-09-18 1999-08-11 Sri International 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents
DE19651415A1 (de) * 1996-12-11 1998-06-18 Henkel Ecolab Gmbh & Co Ohg Verfahren zur Instrumentendesinfektion
BR0215212A (pt) * 2001-12-21 2004-12-07 Novo Nordisk As Ativador de carboxamida ou sulfonamida de glicoquinase, composto, composição farmacêutica, e, uso de um composto
EP1531815B1 (en) 2002-06-27 2014-09-24 Novo Nordisk A/S Glucokinase activators
US20050282814A1 (en) * 2002-10-03 2005-12-22 Targegen, Inc. Vasculostatic agents and methods of use thereof
WO2005066145A1 (en) 2004-01-06 2005-07-21 Novo Nordisk A/S Heteroaryl-ureas and their use as glucokinase activators
NZ551027A (en) 2004-04-08 2011-01-28 Targegen Inc Benzotriazine inhibitors of kinases
PL382308A1 (pl) * 2004-08-25 2007-08-20 Targegen, Inc. Związki heterocykliczne i sposoby stosowania
JP2008543775A (ja) * 2005-06-08 2008-12-04 ターゲジェン インコーポレーティッド 眼の障害を治療するための方法および組成物
ES2382815T3 (es) 2005-07-08 2012-06-13 Novo Nordisk A/S Dicicloalquilcarbamoil ureas como activadores de glucoquinasa
EP2377856A1 (en) 2005-07-14 2011-10-19 Novo Nordisk A/S Urea glucokinase activators
MY167260A (en) * 2005-11-01 2018-08-14 Targegen Inc Bi-aryl meta-pyrimidine inhibitors of kinases
US8133900B2 (en) * 2005-11-01 2012-03-13 Targegen, Inc. Use of bi-aryl meta-pyrimidine inhibitors of kinases
US8604042B2 (en) * 2005-11-01 2013-12-10 Targegen, Inc. Bi-aryl meta-pyrimidine inhibitors of kinases
WO2008084043A1 (en) 2007-01-09 2008-07-17 Novo Nordisk A/S Urea glucokinase activators
WO2008084044A1 (en) 2007-01-11 2008-07-17 Novo Nordisk A/S Urea glucokinase activators
AU2010363329A1 (en) 2010-11-07 2013-05-09 Targegen, Inc. Compositions and methods for treating myelofibrosis
EP2800744A4 (en) * 2011-12-07 2015-06-03 Sri Internat Inc BENZOTRIAZINE OXIDE AS A MEDICAMENT AGAINST MYCOBACTERIUM TUBERCULOSIS
CA3093025A1 (en) 2018-06-12 2019-12-19 Vtv Therapeutics Llc Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs
WO2021167840A1 (en) 2020-02-18 2021-08-26 Vtv Therapeutics Llc Sulfoxide and sulfone glucokinase activators and methods of use thereof
CN115894385B (zh) * 2023-01-09 2025-02-07 中国科学院长春应用化学研究所 替拉扎明衍生物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3957779A (en) * 1972-11-15 1976-05-18 Bayer Aktiengesellschaft Benzo-1,2,4-triazines
US3991189A (en) * 1972-11-15 1976-11-09 Bayer Aktiengesellschaft Microbiocidal methods and compositions using substituted 1,2,4-triazine-1,4-di-N-oxide derivatives
SE7501624L (enExample) * 1974-03-15 1975-09-16 Ciba Geigy Ag

Also Published As

Publication number Publication date
AU6485674A (en) 1975-07-24
DE2404375A1 (de) 1974-08-08
FR2215967B1 (enExample) 1977-01-28
IL44058A (en) 1978-10-31
IE38778B1 (en) 1978-05-24
FR2215967A1 (enExample) 1974-08-30
IL44058A0 (en) 1974-05-16
US4160833A (en) 1979-07-10
AR207145A1 (es) 1976-09-15
IE38778L (en) 1974-08-02
NL7401370A (enExample) 1974-08-06
BE810511A (fr) 1974-08-01
SU589914A3 (ru) 1978-01-25
JPS49124235A (enExample) 1974-11-28
CA1049014A (en) 1979-02-20

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
48S Specification amended (sect. 8/1949)
SP Amendment (slips) printed
PCNP Patent ceased through non-payment of renewal fee