GB1464432A - Indolobenzazepine derivatives - Google Patents
Indolobenzazepine derivativesInfo
- Publication number
- GB1464432A GB1464432A GB1911876A GB1911876A GB1464432A GB 1464432 A GB1464432 A GB 1464432A GB 1911876 A GB1911876 A GB 1911876A GB 1911876 A GB1911876 A GB 1911876A GB 1464432 A GB1464432 A GB 1464432A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- compound
- methyl
- ethyl
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
1464432 Indolobenzazepines ROCHE PRODUCTS Ltd 11 March 1975 [25 March 1974] 19118/76 Divided out of 1464431 Heading C2C Novel compounds of Formula I wherein R is methyl or ethyl are prepared either by removal by conventional methods of group R<SP>4</SP> from a compound of Formula IV wherein R<SP>3</SP> and R<SP>4</SP> are both methyl or ethyl or R<SP>3</SP> is ethyl or methyl and R<SP>4</SP> is benzyl, or by cyclization in situ of the imine formed by reaction of 1,3-dimethylpiperidone and a compound of Formula II Intermediates of Formula IV above are prepared by reaction of formaldehyde and an amine R<SP>3</SP>NHR<SP>4</SP> with a compound of Formula III formed by reaction of methyl ethyl ketone with a compound of Formula II above.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1911876A GB1464432A (en) | 1974-03-25 | 1975-03-11 | Indolobenzazepine derivatives |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1320774A GB1464431A (en) | 1974-03-25 | 1974-03-25 | Indolobenzazepine derivatives and a process for the manufacture thereof |
GB1911876A GB1464432A (en) | 1974-03-25 | 1975-03-11 | Indolobenzazepine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1464432A true GB1464432A (en) | 1977-02-16 |
Family
ID=26249629
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1911876A Expired GB1464432A (en) | 1974-03-25 | 1975-03-11 | Indolobenzazepine derivatives |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1464432A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0024852A1 (en) * | 1979-08-13 | 1981-03-11 | American Home Products Corporation | 2,3-Dihydro-1H-indole derivatives and intermediates therefor, processes for their preparation, pharmaceutical compositions containing these derivatives and their preparation |
-
1975
- 1975-03-11 GB GB1911876A patent/GB1464432A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0024852A1 (en) * | 1979-08-13 | 1981-03-11 | American Home Products Corporation | 2,3-Dihydro-1H-indole derivatives and intermediates therefor, processes for their preparation, pharmaceutical compositions containing these derivatives and their preparation |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |