GB1464432A - Indolobenzazepine derivatives - Google Patents

Indolobenzazepine derivatives

Info

Publication number
GB1464432A
GB1464432A GB1911876A GB1911876A GB1464432A GB 1464432 A GB1464432 A GB 1464432A GB 1911876 A GB1911876 A GB 1911876A GB 1911876 A GB1911876 A GB 1911876A GB 1464432 A GB1464432 A GB 1464432A
Authority
GB
United Kingdom
Prior art keywords
formula
compound
methyl
ethyl
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1911876A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Products Ltd
Original Assignee
Roche Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB1320774A external-priority patent/GB1464431A/en
Application filed by Roche Products Ltd filed Critical Roche Products Ltd
Priority to GB1911876A priority Critical patent/GB1464432A/en
Publication of GB1464432A publication Critical patent/GB1464432A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

1464432 Indolobenzazepines ROCHE PRODUCTS Ltd 11 March 1975 [25 March 1974] 19118/76 Divided out of 1464431 Heading C2C Novel compounds of Formula I wherein R is methyl or ethyl are prepared either by removal by conventional methods of group R<SP>4</SP> from a compound of Formula IV wherein R<SP>3</SP> and R<SP>4</SP> are both methyl or ethyl or R<SP>3</SP> is ethyl or methyl and R<SP>4</SP> is benzyl, or by cyclization in situ of the imine formed by reaction of 1,3-dimethylpiperidone and a compound of Formula II Intermediates of Formula IV above are prepared by reaction of formaldehyde and an amine R<SP>3</SP>NHR<SP>4</SP> with a compound of Formula III formed by reaction of methyl ethyl ketone with a compound of Formula II above.
GB1911876A 1974-03-25 1975-03-11 Indolobenzazepine derivatives Expired GB1464432A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1911876A GB1464432A (en) 1974-03-25 1975-03-11 Indolobenzazepine derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1320774A GB1464431A (en) 1974-03-25 1974-03-25 Indolobenzazepine derivatives and a process for the manufacture thereof
GB1911876A GB1464432A (en) 1974-03-25 1975-03-11 Indolobenzazepine derivatives

Publications (1)

Publication Number Publication Date
GB1464432A true GB1464432A (en) 1977-02-16

Family

ID=26249629

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1911876A Expired GB1464432A (en) 1974-03-25 1975-03-11 Indolobenzazepine derivatives

Country Status (1)

Country Link
GB (1) GB1464432A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0024852A1 (en) * 1979-08-13 1981-03-11 American Home Products Corporation 2,3-Dihydro-1H-indole derivatives and intermediates therefor, processes for their preparation, pharmaceutical compositions containing these derivatives and their preparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0024852A1 (en) * 1979-08-13 1981-03-11 American Home Products Corporation 2,3-Dihydro-1H-indole derivatives and intermediates therefor, processes for their preparation, pharmaceutical compositions containing these derivatives and their preparation

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee