GB1456358A - Triazolobenzodiazepines - Google Patents
TriazolobenzodiazepinesInfo
- Publication number
- GB1456358A GB1456358A GB4176775A GB4176775A GB1456358A GB 1456358 A GB1456358 A GB 1456358A GB 4176775 A GB4176775 A GB 4176775A GB 4176775 A GB4176775 A GB 4176775A GB 1456358 A GB1456358 A GB 1456358A
- Authority
- GB
- United Kingdom
- Prior art keywords
- carried out
- triazolobenzodiazepines
- alkali metal
- iii
- nchr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000460 chlorine Substances 0.000 abstract 5
- 229910052801 chlorine Inorganic materials 0.000 abstract 4
- 229910052794 bromium Inorganic materials 0.000 abstract 3
- 229910052731 fluorine Inorganic materials 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- -1 CF 3 Inorganic materials 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001339 alkali metal compounds Chemical class 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229940035363 muscle relaxants Drugs 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 125000001979 organolithium group Chemical group 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 239000003204 tranquilizing agent Substances 0.000 abstract 1
- 230000002936 tranquilizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US525363A US3910944A (en) | 1974-11-20 | 1974-11-20 | Spiro(cyclopropane-1,4{40 -(4H)-s-triazolo-(4,3-a)(1,4)benzodiazepines) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1456358A true GB1456358A (en) | 1976-11-24 |
Family
ID=24092932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4176775A Expired GB1456358A (en) | 1974-11-20 | 1975-10-13 | Triazolobenzodiazepines |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3910944A (enExample) |
| JP (1) | JPS5165799A (enExample) |
| DE (1) | DE2548737A1 (enExample) |
| FR (1) | FR2291758A1 (enExample) |
| GB (1) | GB1456358A (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1234810A (en) * | 1983-12-19 | 1988-04-05 | Steve Nichols | Non-hygroscopic adinazolam methanesulfonate salt and process therefor |
| US4663321A (en) * | 1984-06-26 | 1987-05-05 | Merck & Co., Inc. | Triazolobenzodiazepines and pharmaceutical use |
| IL105128A0 (en) * | 1992-03-25 | 1994-01-25 | Smithkline Beecham Corp | Processes and intermediates for the preparation of 2-substituted benzaldehydes |
| US5659084A (en) * | 1993-03-25 | 1997-08-19 | Smithkline Beecham Corporation | Processes and intermediates for the preparation of 2-substituted benzaldehydes |
| WO2012075456A1 (en) * | 2010-12-02 | 2012-06-07 | Constellation Pharmaceuticals | Bromodomain inhibitors and uses thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3681343A (en) * | 1971-05-11 | 1972-08-01 | Upjohn Co | 6-phenyl-s-triazolo{8 4,3-a{9 {8 1,4{9 {0 benzodiazepines |
-
1974
- 1974-11-20 US US525363A patent/US3910944A/en not_active Expired - Lifetime
-
1975
- 1975-10-13 GB GB4176775A patent/GB1456358A/en not_active Expired
- 1975-10-15 JP JP50124220A patent/JPS5165799A/ja active Pending
- 1975-10-31 DE DE19752548737 patent/DE2548737A1/de active Pending
- 1975-11-20 FR FR7535547A patent/FR2291758A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5165799A (en) | 1976-06-07 |
| FR2291758B1 (enExample) | 1978-07-28 |
| US3910944A (en) | 1975-10-07 |
| FR2291758A1 (fr) | 1976-06-18 |
| DE2548737A1 (de) | 1976-05-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1147379A (en) | 4-alkyl-dialkoxy-ª‡-methylphenethylamines and pharmacologically acceptable salts | |
| GB1456358A (en) | Triazolobenzodiazepines | |
| GB1399230A (en) | Pyrazolodiazepine compounds and methods for their production | |
| GB1495176A (en) | Derivatives of 5h-dibenz(b,f)azepine and process for the manufacture thereof | |
| GB1475314A (en) | Phenyl-propylamine derivatives | |
| GB1451902A (en) | Bromo dihydrolysergic acid | |
| GB1508276A (en) | Oxamic and dioxamic acid derivatives | |
| GB1348449A (en) | Benzodiazepine derivatives | |
| GB1449426A (en) | Phenoxyalkylamine derivatives and preparation therof | |
| GB1431259A (en) | 1-substituted-6-phenyl-4h-s-triazolo- 4,3-a- 1,4- benzodiazepines | |
| GB1474305A (en) | Benzodiazepine derivatives | |
| GB1373271A (en) | Indoles | |
| GB1302353A (enExample) | ||
| GB1290300A (enExample) | ||
| GB1275875A (en) | 3-amino-2-(3,4-disubstituted)bicyclo(2.2.2)octan-2-ols | |
| GB1470748A (en) | 6-2-pyridyl-4h-s-triazolo-4,3-a-1,4-benzodiazepines | |
| GB1222294A (en) | Oxazinobenzodiazepine derivatives | |
| GB1463908A (en) | 1-dimethylamino-methyl-6-substituted-4h-s-triazolo-4,3-a- 1,4-benzodiazepine | |
| GB1302352A (enExample) | ||
| GB1325630A (en) | Benzodiazepine derivatives and a process for the manufacture thereof | |
| GB1298300A (en) | Benzodiazepines | |
| GB1444529A (en) | Benzodiazepine derivatives | |
| GB1329130A (en) | Isoindolo 1,2-b benzothiazol-11 -4bh- one 5-oxides | |
| GB1472487A (en) | Benzodiazepine derivatives | |
| GB1344655A (en) | Diphenylmethyl aminopropyl ethers |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |