GB1455738A - Unsaturated nitriles - Google Patents
Unsaturated nitrilesInfo
- Publication number
- GB1455738A GB1455738A GB456076A GB456076A GB1455738A GB 1455738 A GB1455738 A GB 1455738A GB 456076 A GB456076 A GB 456076A GB 456076 A GB456076 A GB 456076A GB 1455738 A GB1455738 A GB 1455738A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydroxy
- formyl
- alkyl
- methylsulphonylethyl
- dimethoxybenzoate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
- C07C45/515—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an acetalised, ketalised hemi-acetalised, or hemi-ketalised hydroxyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1455738 Nitriles F HOFFMANN-LA ROCHE & CO AG 26 July 1974 [27 July 1973] 04560/76 Divided out of 1455736 Heading C2C Compounds of the general formula (R<SP>1,2</SP> = alkyl, alkenyl; Y = leaving group; A<SP>2</SP> = CF 3 , CN, alkoxycarbonyl, CR<SP>8</SP>R<SP>9</SP>R<SP>13</SP>; R<SP>8,9</SP> = H, alkyl; R<SP>13</SP> = OH, alkoxy, NR<SP>3</SP>R<SP>4</SP>; R<SP>3,4</SP> = H, alkyl, alkanoyl) are prepared by standard methods, e.g. reacting the corresponding compound containing a formyl or 1-hydroxy- 2-methylsulphonylethyl group para to A<SP>2</SP> with YCH 2 CH 2 CN, optionally followed by replacement of the leaving group by another. The preparation of methyl 4-formyl and chloroformyl - 2,6 - dimethoxybenzoate, 1 - ethyl and diethyl 2,6 - diethoxyterephthalate, ethyl 4- formyl and chloroformyl - 2,6 - diethoxybenzoate, methyl 4-cyano, aminomethyl and acetamidomethyl - 3,5 - dimethoxybenzoate, N - (2,6 - dimethoxy - 4 - methylsulphonylacetylbenzyl)acetamide, N - [2,6 - dimethoxy - 4 - (1 - hydroxy - 2- methylsulphonylethyl)benzyl] - acetamide and 4- (1 - hydroxyethyl), (1 - hydroxy - 1 - methylethyl), (1 - hydroxy - 1 - ethylpropyl) and (1 - hydroxypropyl)-3,5-dimethoxybenzaldehyde is described.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1099573A CH598231A5 (en) | 1973-07-27 | 1973-07-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1455738A true GB1455738A (en) | 1976-11-17 |
Family
ID=4368954
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB455976A Expired GB1455737A (en) | 1973-07-27 | 1974-07-26 | Acetals |
GB3316974A Expired GB1455736A (en) | 1973-07-27 | 1974-07-26 | Benzylpyrimidine derivatives |
GB456176A Expired GB1455739A (en) | 1973-07-27 | 1974-07-26 | Acid amides |
GB456076A Expired GB1455738A (en) | 1973-07-27 | 1974-07-26 | Unsaturated nitriles |
GB456276A Expired GB1455740A (en) | 1973-07-27 | 1974-07-26 | Benzylpyrimidine derivatives |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB455976A Expired GB1455737A (en) | 1973-07-27 | 1974-07-26 | Acetals |
GB3316974A Expired GB1455736A (en) | 1973-07-27 | 1974-07-26 | Benzylpyrimidine derivatives |
GB456176A Expired GB1455739A (en) | 1973-07-27 | 1974-07-26 | Acid amides |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB456276A Expired GB1455740A (en) | 1973-07-27 | 1974-07-26 | Benzylpyrimidine derivatives |
Country Status (11)
Country | Link |
---|---|
JP (1) | JPS5041876A (en) |
BE (1) | BE818131A (en) |
CA (1) | CA1026759A (en) |
CH (1) | CH598231A5 (en) |
DE (1) | DE2435934A1 (en) |
DK (1) | DK135374B (en) |
FR (1) | FR2238496B1 (en) |
GB (5) | GB1455737A (en) |
NL (1) | NL7410100A (en) |
SE (1) | SE415975B (en) |
ZA (1) | ZA744512B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1084498A (en) | 1977-05-05 | 1980-08-26 | Alexander E. Wick | Benzylpyrimidines and process for the preparation thereof |
HU188588B (en) * | 1982-08-13 | 1986-04-28 | Egyt Gyogyszervegyeszeti Gyar | Process for the production of 2,4-diamino-5-benzyl-pyrimidine-derivatives |
KR100962732B1 (en) | 2005-06-02 | 2010-06-09 | 에프. 호프만-라 로슈 아게 | Piperidin-4-yl-amide derivatives and their use as sst receptor subtype 5 antagonists |
US7855194B2 (en) | 2006-03-27 | 2010-12-21 | Hoffmann-La Roche Inc. | Pyrimidine, quinazoline, pteridine and triazine derivatives |
-
1973
- 1973-07-27 CH CH1099573A patent/CH598231A5/xx not_active IP Right Cessation
-
1974
- 1974-07-11 DK DK374174AA patent/DK135374B/en not_active IP Right Cessation
- 1974-07-15 ZA ZA00744512A patent/ZA744512B/en unknown
- 1974-07-19 FR FR7425210A patent/FR2238496B1/fr not_active Expired
- 1974-07-25 DE DE2435934A patent/DE2435934A1/en not_active Ceased
- 1974-07-26 GB GB455976A patent/GB1455737A/en not_active Expired
- 1974-07-26 GB GB3316974A patent/GB1455736A/en not_active Expired
- 1974-07-26 GB GB456176A patent/GB1455739A/en not_active Expired
- 1974-07-26 JP JP49085239A patent/JPS5041876A/ja active Pending
- 1974-07-26 NL NL7410100A patent/NL7410100A/en not_active Application Discontinuation
- 1974-07-26 GB GB456076A patent/GB1455738A/en not_active Expired
- 1974-07-26 CA CA205,706A patent/CA1026759A/en not_active Expired
- 1974-07-26 GB GB456276A patent/GB1455740A/en not_active Expired
- 1974-07-26 SE SE7409733A patent/SE415975B/en unknown
- 1974-07-26 BE BE146980A patent/BE818131A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SE415975B (en) | 1980-11-17 |
DK135374B (en) | 1977-04-18 |
CA1026759A (en) | 1978-02-21 |
SE7409733L (en) | 1975-01-28 |
AU7148874A (en) | 1976-01-22 |
CH598231A5 (en) | 1978-04-28 |
JPS5041876A (en) | 1975-04-16 |
DK374174A (en) | 1975-04-01 |
GB1455739A (en) | 1976-11-17 |
GB1455736A (en) | 1976-11-17 |
DE2435934A1 (en) | 1975-02-13 |
BE818131A (en) | 1975-01-27 |
FR2238496B1 (en) | 1977-09-09 |
NL7410100A (en) | 1975-01-29 |
ZA744512B (en) | 1975-09-24 |
DK135374C (en) | 1977-10-03 |
GB1455737A (en) | 1976-11-17 |
FR2238496A1 (en) | 1975-02-21 |
GB1455740A (en) | 1976-11-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |