GB1455220A - - Google Patents
Info
- Publication number
- GB1455220A GB1455220A GB3979974A GB3979974A GB1455220A GB 1455220 A GB1455220 A GB 1455220A GB 3979974 A GB3979974 A GB 3979974A GB 3979974 A GB3979974 A GB 3979974A GB 1455220 A GB1455220 A GB 1455220A
- Authority
- GB
- United Kingdom
- Prior art keywords
- dihydrospiro
- furan
- give
- steroids
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 alkali metal cyanide Chemical class 0.000 abstract 4
- 150000003431 steroids Chemical class 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 2
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 229940030606 diuretics Drugs 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39723273A | 1973-09-14 | 1973-09-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1455220A true GB1455220A (en:Method) | 1976-11-10 |
Family
ID=23570365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3979974A Expired GB1455220A (en:Method) | 1973-09-14 | 1974-09-12 |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS5850239B2 (en:Method) |
| CA (1) | CA1033354A (en:Method) |
| CH (1) | CH602791A5 (en:Method) |
| DE (1) | DE2443746A1 (en:Method) |
| FR (1) | FR2243701B1 (en:Method) |
| GB (1) | GB1455220A (en:Method) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA009176B1 (ru) * | 1995-12-11 | 2007-12-28 | Дж.Д.Серл Энд Ко. | Способ получения 7-альфа-карбоксил-9,11-эпоксистероидов и промежуточных продуктов, используемых для их получения, и общий способ эпоксидирования по олефиновым двойным связям |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1170299A3 (en) * | 1995-12-11 | 2004-11-10 | G.D. Searle & Co. | Intermediates useful in the preparation of 9,11-epoxy steroids and methods for their production |
| ATE375992T1 (de) | 1996-12-11 | 2007-11-15 | Searle Llc | Epoxidierungsverfahren |
| US6887991B1 (en) | 1996-12-11 | 2005-05-03 | G. D. Searle & Company | Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein |
| EP1223174A3 (en) * | 1996-12-11 | 2005-03-16 | G.D. Searle & Co. | Processes for preparation of 3-keto-7alpha-alkoxycarbonyl-delta-4,5- steroids and intermediates useful therein |
| US7235655B2 (en) | 2002-03-22 | 2007-06-26 | Pharmacia & Upjohn Company | Processes to prepare eplerenone |
| EP1794177A2 (en) * | 2004-09-09 | 2007-06-13 | Pharmacia Corporation | Process for preparing 7 -alkoxycarbonyl substituted steroids |
-
1974
- 1974-09-12 DE DE19742443746 patent/DE2443746A1/de not_active Withdrawn
- 1974-09-12 GB GB3979974A patent/GB1455220A/en not_active Expired
- 1974-09-13 CA CA209,165A patent/CA1033354A/en not_active Expired
- 1974-09-13 JP JP49105924A patent/JPS5850239B2/ja not_active Expired
- 1974-09-13 FR FR7431120A patent/FR2243701B1/fr not_active Expired
- 1974-09-16 CH CH1254474A patent/CH602791A5/xx not_active IP Right Cessation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA009176B1 (ru) * | 1995-12-11 | 2007-12-28 | Дж.Д.Серл Энд Ко. | Способ получения 7-альфа-карбоксил-9,11-эпоксистероидов и промежуточных продуктов, используемых для их получения, и общий способ эпоксидирования по олефиновым двойным связям |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2443746A1 (de) | 1975-03-20 |
| FR2243701B1 (en:Method) | 1978-07-21 |
| JPS5850239B2 (ja) | 1983-11-09 |
| CH602791A5 (en:Method) | 1978-08-15 |
| CA1033354A (en) | 1978-06-20 |
| JPS5053363A (en:Method) | 1975-05-12 |
| FR2243701A1 (en:Method) | 1975-04-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |