GB1454975A - Process for the preparation of 7-amino-delta3-cephem derivatives - Google Patents
Process for the preparation of 7-amino-delta3-cephem derivativesInfo
- Publication number
- GB1454975A GB1454975A GB825575A GB825575A GB1454975A GB 1454975 A GB1454975 A GB 1454975A GB 825575 A GB825575 A GB 825575A GB 825575 A GB825575 A GB 825575A GB 1454975 A GB1454975 A GB 1454975A
- Authority
- GB
- United Kingdom
- Prior art keywords
- amino
- cephem derivatives
- delta3
- preparation
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C12P35/02—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by desacylation of the substituent in the 7 position
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Cephalosporin Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Abstract
7-Amino- DELTA <3>-cephem derivatives of the following formula <IMAGE> are prepared, in which the substituents are as defined in Claim 1. The said cephem derivatives are obtained by bringing an appropriately substituted acetamidodesacetoxycephalosporanic acid or a derivative thereof into contact with penicillin acylase. This is covalently bonded to a water-soluble support and can additionally be present in a form enclosed in a water-insoluble support material. The process product can be used as an intermediate for the synthesis of antimicrobial substances.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2409569A DE2409569C2 (en) | 1974-02-28 | 1974-02-28 | Process for the preparation of 7-amino-Ω3-cephem derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1454975A true GB1454975A (en) | 1976-11-10 |
Family
ID=5908688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB825575A Expired GB1454975A (en) | 1974-02-28 | 1975-02-27 | Process for the preparation of 7-amino-delta3-cephem derivatives |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS5724118B2 (en) |
| AT (1) | AT338974B (en) |
| AU (1) | AU7855275A (en) |
| BE (1) | BE825999A (en) |
| CA (1) | CA1048950A (en) |
| CH (1) | CH611302A5 (en) |
| CS (1) | CS185675B2 (en) |
| DD (1) | DD117073A5 (en) |
| DE (1) | DE2409569C2 (en) |
| DK (1) | DK78175A (en) |
| ES (1) | ES435151A1 (en) |
| FI (1) | FI750557A (en) |
| FR (1) | FR2262667B1 (en) |
| GB (1) | GB1454975A (en) |
| HK (1) | HK67179A (en) |
| IE (1) | IE41134B1 (en) |
| IL (1) | IL46698A (en) |
| KE (1) | KE2992A (en) |
| LU (1) | LU71925A1 (en) |
| NL (1) | NL7502291A (en) |
| NO (1) | NO750383L (en) |
| SE (1) | SE7502230L (en) |
| ZA (1) | ZA751230B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002085913A1 (en) * | 2001-04-18 | 2002-10-31 | Otsuka Kagaku Kabushiki Kaisha | Penicillin and cephalosporin compound |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50123885A (en) * | 1974-03-15 | 1975-09-29 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL39158A (en) * | 1971-04-28 | 1977-08-31 | Snam Progetti | Enzymatic scission and synthesis of penicillins and cephalosporins |
-
1974
- 1974-02-28 DE DE2409569A patent/DE2409569C2/en not_active Expired
-
1975
- 1975-02-06 NO NO750383A patent/NO750383L/no unknown
- 1975-02-25 CA CA75220717A patent/CA1048950A/en not_active Expired
- 1975-02-25 AU AU78552/75A patent/AU7855275A/en not_active Expired
- 1975-02-25 IL IL46698A patent/IL46698A/en unknown
- 1975-02-26 JP JP2299275A patent/JPS5724118B2/ja not_active Expired
- 1975-02-26 BE BE153756A patent/BE825999A/en unknown
- 1975-02-26 CH CH238475A patent/CH611302A5/en not_active IP Right Cessation
- 1975-02-26 CS CS7500001289A patent/CS185675B2/en unknown
- 1975-02-26 FI FI750557A patent/FI750557A/fi not_active Application Discontinuation
- 1975-02-26 LU LU71925A patent/LU71925A1/xx unknown
- 1975-02-26 NL NL7502291A patent/NL7502291A/en not_active Application Discontinuation
- 1975-02-26 AT AT146575A patent/AT338974B/en not_active IP Right Cessation
- 1975-02-26 DD DD184435A patent/DD117073A5/xx unknown
- 1975-02-27 ZA ZA00751230A patent/ZA751230B/en unknown
- 1975-02-27 DK DK78175*#A patent/DK78175A/da unknown
- 1975-02-27 ES ES435151A patent/ES435151A1/en not_active Expired
- 1975-02-27 IE IE416/75A patent/IE41134B1/en unknown
- 1975-02-27 GB GB825575A patent/GB1454975A/en not_active Expired
- 1975-02-27 SE SE7502230A patent/SE7502230L/xx unknown
- 1975-02-28 FR FR7506375A patent/FR2262667B1/fr not_active Expired
-
1979
- 1979-09-11 KE KE2992A patent/KE2992A/en unknown
- 1979-09-20 HK HK671/79A patent/HK67179A/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002085913A1 (en) * | 2001-04-18 | 2002-10-31 | Otsuka Kagaku Kabushiki Kaisha | Penicillin and cephalosporin compound |
Also Published As
| Publication number | Publication date |
|---|---|
| SE7502230L (en) | 1975-08-29 |
| DD117073A5 (en) | 1975-12-20 |
| AT338974B (en) | 1977-09-26 |
| NO750383L (en) | 1975-08-29 |
| BE825999A (en) | 1975-08-26 |
| DE2409569A1 (en) | 1975-09-11 |
| JPS5724118B2 (en) | 1982-05-22 |
| JPS50123888A (en) | 1975-09-29 |
| NL7502291A (en) | 1975-09-01 |
| FI750557A (en) | 1975-08-29 |
| ZA751230B (en) | 1976-01-28 |
| LU71925A1 (en) | 1975-12-09 |
| AU7855275A (en) | 1976-08-26 |
| DE2409569C2 (en) | 1982-02-18 |
| FR2262667B1 (en) | 1978-07-13 |
| ATA146575A (en) | 1977-01-15 |
| CH611302A5 (en) | 1979-05-31 |
| IE41134L (en) | 1975-08-28 |
| CS185675B2 (en) | 1978-10-31 |
| CA1048950A (en) | 1979-02-20 |
| HK67179A (en) | 1979-09-28 |
| IE41134B1 (en) | 1979-10-24 |
| KE2992A (en) | 1979-09-28 |
| IL46698A0 (en) | 1975-04-25 |
| DK78175A (en) | 1975-10-20 |
| IL46698A (en) | 1978-01-31 |
| FR2262667A1 (en) | 1975-09-26 |
| ES435151A1 (en) | 1976-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |