GB1450540A - Composition method and device for determining bilirubin and urobilinogen - Google Patents

Composition method and device for determining bilirubin and urobilinogen

Info

Publication number
GB1450540A
GB1450540A GB6022173A GB6022173A GB1450540A GB 1450540 A GB1450540 A GB 1450540A GB 6022173 A GB6022173 A GB 6022173A GB 6022173 A GB6022173 A GB 6022173A GB 1450540 A GB1450540 A GB 1450540A
Authority
GB
United Kingdom
Prior art keywords
urobilinogen
bilirubin
determination
compound
aqueous solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB6022173A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Publication of GB1450540A publication Critical patent/GB1450540A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/728—Bilirubin; including biliverdin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/903—Diazo reactions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N
    • Y10T436/146666—Bile pigment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

1450540 Determination of bilirubin and urobilinogen MILES LABORATORIES Inc 31 Dec 1973 [2 Jan 1973] 60221/73 Heading G1B A test composition used in the determination of both bilirubin and urobilinogen in aqueous solution comprises a compound of Formula in which R<SP>1</SP> and R<SP>11</SP>, which may be the same or different, are anions and in which the benzene rings may be substituted by -H, -CH 3 , -OCH 3 , -SO 3 H or -Cl, and an acid constituent which may be a solid adduct of a Friedel-Crafts salt and an organic Lewis base, the adduct being hydrolysable to release a mineral acid, or a solid water-soluble organic or inorganic acid. The composition may be in the form of a dry powder or tablet containing an effervescent couple or may be incorporated in to or on to a carrier member, itself attached to a holder or support. A method for the determination of both bilirubin and urobilinogen in an aqueous solution comprises contacting the aqueous solution with a compound of formula as above or a composition of the compound with a carrier or diluent. Preferred compounds are 4, 4<SP>1</SP>-diazobiphenyl compounds.
GB6022173A 1973-01-02 1973-12-31 Composition method and device for determining bilirubin and urobilinogen Expired GB1450540A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00320117A US3814586A (en) 1973-01-02 1973-01-02 Composition,method and device for determining bilirubin and urobilinogen

Publications (1)

Publication Number Publication Date
GB1450540A true GB1450540A (en) 1976-09-22

Family

ID=23244963

Family Applications (1)

Application Number Title Priority Date Filing Date
GB6022173A Expired GB1450540A (en) 1973-01-02 1973-12-31 Composition method and device for determining bilirubin and urobilinogen

Country Status (5)

Country Link
US (1) US3814586A (en)
JP (1) JPS4999091A (en)
CA (1) CA1025337A (en)
DE (1) DE2364844A1 (en)
GB (1) GB1450540A (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3915649A (en) * 1974-08-14 1975-10-28 American Cyanamid Co Bilirubin test material
DE2521402C3 (en) * 1975-05-14 1979-07-26 Behringwerke Ag, 3550 Marburg Diagnostic agent for the detection of urobilinogen
US4078892A (en) * 1975-06-30 1978-03-14 Becton, Dickinson And Company Novel means and method for diagnostic quantitation of serum or plasma bilirubin
US4288344A (en) * 1976-11-22 1981-09-08 Andre Reiss Stable diazonium salt generator for improved marijuana analysis
US4069017A (en) * 1977-01-14 1978-01-17 Eastman Kodak Company Colorimetric assay for bilirubin
DE2855363B1 (en) * 1978-12-21 1980-05-29 Boehringer Mannheim Gmbh Control reagent for test strips for the detection of urobilinogen in urine
US4311483A (en) * 1979-06-18 1982-01-19 Beckman Instruments, Inc. Kinetic method for directly determining total bilirubin
US4325908A (en) * 1980-02-20 1982-04-20 Warner-Lambert Company Theophylline test
US4405718A (en) * 1981-07-20 1983-09-20 Miles Laboratories, Inc. Method and composition for urobilinogen control standard
US4468467A (en) * 1982-02-01 1984-08-28 Eastman Kodak Company Diazonium salt for bilirubin assay
DE3225331A1 (en) * 1982-07-07 1984-01-12 Boehringer Mannheim Gmbh, 6800 Mannheim METHOD FOR DETERMINING DIRECT AND TOTAL BILIRUBIN, AND REAGENT SUITABLE FOR THIS
US5736408A (en) * 1994-11-23 1998-04-07 Carter; Jesse M. Method for the detection of urobilinogen in urine on an automated analyzer
US5935861A (en) * 1997-11-21 1999-08-10 Boehringer Mannheim Corporation Diazonium ion assay reagents and methods for their use
US8012761B2 (en) * 2006-12-14 2011-09-06 Kimberly-Clark Worldwide, Inc. Detection of formaldehyde in urine samples
US7846383B2 (en) * 2006-12-15 2010-12-07 Kimberly-Clark Worldwide, Inc. Lateral flow assay device and absorbent article containing same
CN101122604B (en) * 2007-08-28 2011-08-17 石同才 Reagent kit for determining serum bilirubin by fast blue B method
WO2015015517A1 (en) * 2013-07-31 2015-02-05 Council Of Scientific & Industrial Research Water soluble polyfluorene functionalized with glucuronic acid useful in bilirubin sensing
WO2019089768A1 (en) * 2017-11-01 2019-05-09 William Marsh Rice University Low resource device and system for measurement of bilirubin levels

Also Published As

Publication number Publication date
JPS4999091A (en) 1974-09-19
DE2364844A1 (en) 1974-07-18
US3814586A (en) 1974-06-04
CA1025337A (en) 1978-01-31

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee