GB1445630A - Prostaglandin derivatives - Google Patents
Prostaglandin derivativesInfo
- Publication number
- GB1445630A GB1445630A GB386476A GB386476A GB1445630A GB 1445630 A GB1445630 A GB 1445630A GB 386476 A GB386476 A GB 386476A GB 386476 A GB386476 A GB 386476A GB 1445630 A GB1445630 A GB 1445630A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydroxy
- octenyl
- trans
- hydrogenating
- cis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003180 prostaglandins Chemical class 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- HZNVUJQVZSTENZ-UHFFFAOYSA-N 2,3-dichloro-5,6-dicyano-1,4-benzoquinone Chemical compound ClC1=C(Cl)C(=O)C(C#N)=C(C#N)C1=O HZNVUJQVZSTENZ-UHFFFAOYSA-N 0.000 abstract 2
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 2
- -1 3 - oxooctyl Chemical group 0.000 abstract 1
- KPSZWAJWFMFMFF-UHFFFAOYSA-N delta-Hexylen-alpha-carbonsaeure Natural products CC=CCCCC(O)=O KPSZWAJWFMFMFF-UHFFFAOYSA-N 0.000 abstract 1
- MNWFXJYAOYHMED-UHFFFAOYSA-N hexane carboxylic acid Natural products CCCCCCC(O)=O MNWFXJYAOYHMED-UHFFFAOYSA-N 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- LROBJRRFCPYLIT-UHFFFAOYSA-M magnesium;ethyne;bromide Chemical compound [Mg+2].[Br-].[C-]#C LROBJRRFCPYLIT-UHFFFAOYSA-M 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- QBERHIJABFXGRZ-UHFFFAOYSA-M rhodium;triphenylphosphane;chloride Chemical compound [Cl-].[Rh].C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1.C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1.C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1 QBERHIJABFXGRZ-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30157172A | 1972-10-27 | 1972-10-27 | |
| US383007A US3922302A (en) | 1973-07-26 | 1973-07-26 | 15-Ethynyl-11-deoxy PGE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1445630A true GB1445630A (en) | 1976-08-11 |
Family
ID=26972455
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB386476A Expired GB1445630A (en) | 1972-10-27 | 1973-10-18 | Prostaglandin derivatives |
| GB4860373A Expired GB1445628A (en) | 1972-10-27 | 1973-10-18 | Prostaglandin derivatives |
| GB386376A Expired GB1445629A (en) | 1972-10-27 | 1973-10-18 | Prostaglandin derivatives |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4860373A Expired GB1445628A (en) | 1972-10-27 | 1973-10-18 | Prostaglandin derivatives |
| GB386376A Expired GB1445629A (en) | 1972-10-27 | 1973-10-18 | Prostaglandin derivatives |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS4980043A (enExample) |
| CA (1) | CA1018970A (enExample) |
| DE (1) | DE2353788A1 (enExample) |
| FR (1) | FR2204422B1 (enExample) |
| GB (3) | GB1445630A (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4091015A (en) * | 1972-10-27 | 1978-05-23 | American Home Products Corporation | 15-Substituted prostanoic acids |
| DE2907118A1 (de) * | 1979-02-20 | 1980-09-04 | Schering Ag | Neue prostacyclin-derivate und verfahren zu ihrer herstellung |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3671570A (en) * | 1970-07-30 | 1972-06-20 | Ayerst Mckenna & Harrison | Derivatives of 9-oxo-15-hydroxyprostanoic acid, homologs thereof and their preparation |
| BE794516A (fr) * | 1972-01-26 | 1973-05-16 | Wisconsin Alumni Res Found | Nouvelles prostaglandines et leur procede de preparation |
-
1973
- 1973-10-12 CA CA183,241A patent/CA1018970A/en not_active Expired
- 1973-10-18 GB GB386476A patent/GB1445630A/en not_active Expired
- 1973-10-18 GB GB4860373A patent/GB1445628A/en not_active Expired
- 1973-10-18 GB GB386376A patent/GB1445629A/en not_active Expired
- 1973-10-26 FR FR7338302A patent/FR2204422B1/fr not_active Expired
- 1973-10-26 DE DE19732353788 patent/DE2353788A1/de not_active Withdrawn
- 1973-10-27 JP JP12116473A patent/JPS4980043A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE2353788A1 (de) | 1974-05-09 |
| GB1445628A (en) | 1976-08-11 |
| CA1018970A (en) | 1977-10-11 |
| GB1445629A (en) | 1976-08-11 |
| FR2204422B1 (enExample) | 1977-11-10 |
| JPS4980043A (enExample) | 1974-08-02 |
| FR2204422A1 (enExample) | 1974-05-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 429A | Application made for amendment of specification (sect. 29/1949) | ||
| 429H | Application (made) for amendment of specification now open to opposition (sect. 29/1949) | ||
| 429D | Case decided by the comptroller ** specification amended (sect. 29/1949) | ||
| SPA | Amended specification published | ||
| PCNP | Patent ceased through non-payment of renewal fee |