GB1445324A - Derivatives of substituted tetrahydro-m-oxazines - Google Patents
Derivatives of substituted tetrahydro-m-oxazinesInfo
- Publication number
- GB1445324A GB1445324A GB1208975A GB1208975A GB1445324A GB 1445324 A GB1445324 A GB 1445324A GB 1208975 A GB1208975 A GB 1208975A GB 1208975 A GB1208975 A GB 1208975A GB 1445324 A GB1445324 A GB 1445324A
- Authority
- GB
- United Kingdom
- Prior art keywords
- substituted
- anticholinergic
- oxazines
- derivatives
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 Substituted Chemical class 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000001078 anti-cholinergic effect Effects 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical group [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000002269 analeptic agent Substances 0.000 abstract 1
- 230000003555 analeptic effect Effects 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 239000000812 cholinergic antagonist Substances 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 230000001670 myorelaxant effect Effects 0.000 abstract 1
- 230000002276 neurotropic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
- ZWZVWGITAAIFPS-UHFFFAOYSA-N thiophosgene Chemical compound ClC(Cl)=S ZWZVWGITAAIFPS-UHFFFAOYSA-N 0.000 abstract 1
- 230000002936 tranquilizing effect Effects 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
- C07D265/08—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7412388A FR2269950B2 (enExample) | 1974-04-09 | 1974-04-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1445324A true GB1445324A (en) | 1976-08-11 |
Family
ID=9137438
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1208975A Expired GB1445324A (en) | 1974-04-09 | 1975-03-24 | Derivatives of substituted tetrahydro-m-oxazines |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS50142523A (enExample) |
| BE (1) | BE827650R (enExample) |
| CA (1) | CA1064033A (enExample) |
| CH (1) | CH568997A5 (enExample) |
| DE (1) | DE2513229A1 (enExample) |
| ES (1) | ES436233A2 (enExample) |
| FR (1) | FR2269950B2 (enExample) |
| GB (1) | GB1445324A (enExample) |
| IT (1) | IT1044488B (enExample) |
| LU (1) | LU72236A1 (enExample) |
| NL (1) | NL7504192A (enExample) |
-
1974
- 1974-04-09 FR FR7412388A patent/FR2269950B2/fr not_active Expired
-
1975
- 1975-03-20 CH CH357575A patent/CH568997A5/xx not_active IP Right Cessation
- 1975-03-24 GB GB1208975A patent/GB1445324A/en not_active Expired
- 1975-03-25 DE DE19752513229 patent/DE2513229A1/de not_active Withdrawn
- 1975-04-02 ES ES436233A patent/ES436233A2/es not_active Expired
- 1975-04-07 BE BE155167A patent/BE827650R/xx active
- 1975-04-07 LU LU72236A patent/LU72236A1/xx unknown
- 1975-04-08 JP JP4269175A patent/JPS50142523A/ja active Pending
- 1975-04-08 IT IT6789275A patent/IT1044488B/it active
- 1975-04-08 NL NL7504192A patent/NL7504192A/xx unknown
- 1975-04-09 CA CA224,203A patent/CA1064033A/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IT1044488B (it) | 1980-03-20 |
| FR2269950B2 (enExample) | 1978-07-28 |
| FR2269950A2 (enExample) | 1975-12-05 |
| LU72236A1 (enExample) | 1976-03-02 |
| JPS50142523A (enExample) | 1975-11-17 |
| DE2513229A1 (de) | 1975-10-30 |
| BE827650R (fr) | 1975-10-07 |
| ES436233A2 (es) | 1977-03-01 |
| CH568997A5 (enExample) | 1975-11-14 |
| CA1064033A (fr) | 1979-10-09 |
| NL7504192A (nl) | 1975-10-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |