GB1445324A - Derivatives of substituted tetrahydro-m-oxazines - Google Patents

Derivatives of substituted tetrahydro-m-oxazines

Info

Publication number
GB1445324A
GB1445324A GB1208975A GB1208975A GB1445324A GB 1445324 A GB1445324 A GB 1445324A GB 1208975 A GB1208975 A GB 1208975A GB 1208975 A GB1208975 A GB 1208975A GB 1445324 A GB1445324 A GB 1445324A
Authority
GB
United Kingdom
Prior art keywords
substituted
anticholinergic
oxazines
derivatives
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1208975A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Publication of GB1445324A publication Critical patent/GB1445324A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/061,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
    • C07D265/081,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1445324 Substituted - 1,3 - oxazimes DELALANDE SA 24 March 1975 [9 April 1974] 12089/75 Addition to 1359751 Heading C2C Novel compounds of the Formula I wherein Ar is a phenyl radical substituted by one or two halogens selected from chlorine and fluorine, one or two C 1-4 alkyl, one or two methoxy or a trifluoromethyl, benzyloxy or methylcarbonylamino may be prepared by reducing a cyano compound to ArOCH 2 CHOHCH 2 CH 2 NH 2 followed by reaction with thiophosgene to yield which cyclizes on heating to the required compound. Pharmaceutical compositions of the compounds I with the usual excipients show antidepressive, neurotropic, sedative, anticataleptisant, anticonvulsivant, tranquillizing, myorelaxant, analgesic, anti - inflammatory, anti - ulcerous, antibronchoconstrictive, anticholinergic, vasodilatory, cardiovascular analeptic, hypotensive and central anticholinergic properties when administered orally, parenterally or rectally.
GB1208975A 1974-04-09 1975-03-24 Derivatives of substituted tetrahydro-m-oxazines Expired GB1445324A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7412388A FR2269950B2 (en) 1974-04-09 1974-04-09

Publications (1)

Publication Number Publication Date
GB1445324A true GB1445324A (en) 1976-08-11

Family

ID=9137438

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1208975A Expired GB1445324A (en) 1974-04-09 1975-03-24 Derivatives of substituted tetrahydro-m-oxazines

Country Status (11)

Country Link
JP (1) JPS50142523A (en)
BE (1) BE827650R (en)
CA (1) CA1064033A (en)
CH (1) CH568997A5 (en)
DE (1) DE2513229A1 (en)
ES (1) ES436233A2 (en)
FR (1) FR2269950B2 (en)
GB (1) GB1445324A (en)
IT (1) IT1044488B (en)
LU (1) LU72236A1 (en)
NL (1) NL7504192A (en)

Also Published As

Publication number Publication date
FR2269950B2 (en) 1978-07-28
DE2513229A1 (en) 1975-10-30
CA1064033A (en) 1979-10-09
JPS50142523A (en) 1975-11-17
IT1044488B (en) 1980-03-20
LU72236A1 (en) 1976-03-02
FR2269950A2 (en) 1975-12-05
NL7504192A (en) 1975-10-13
BE827650R (en) 1975-10-07
ES436233A2 (en) 1977-03-01
CH568997A5 (en) 1975-11-14

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee