GB1445324A - Derivatives of substituted tetrahydro-m-oxazines - Google Patents
Derivatives of substituted tetrahydro-m-oxazinesInfo
- Publication number
- GB1445324A GB1445324A GB1208975A GB1208975A GB1445324A GB 1445324 A GB1445324 A GB 1445324A GB 1208975 A GB1208975 A GB 1208975A GB 1208975 A GB1208975 A GB 1208975A GB 1445324 A GB1445324 A GB 1445324A
- Authority
- GB
- United Kingdom
- Prior art keywords
- substituted
- anticholinergic
- oxazines
- derivatives
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
- C07D265/08—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1445324 Substituted - 1,3 - oxazimes DELALANDE SA 24 March 1975 [9 April 1974] 12089/75 Addition to 1359751 Heading C2C Novel compounds of the Formula I wherein Ar is a phenyl radical substituted by one or two halogens selected from chlorine and fluorine, one or two C 1-4 alkyl, one or two methoxy or a trifluoromethyl, benzyloxy or methylcarbonylamino may be prepared by reducing a cyano compound to ArOCH 2 CHOHCH 2 CH 2 NH 2 followed by reaction with thiophosgene to yield which cyclizes on heating to the required compound. Pharmaceutical compositions of the compounds I with the usual excipients show antidepressive, neurotropic, sedative, anticataleptisant, anticonvulsivant, tranquillizing, myorelaxant, analgesic, anti - inflammatory, anti - ulcerous, antibronchoconstrictive, anticholinergic, vasodilatory, cardiovascular analeptic, hypotensive and central anticholinergic properties when administered orally, parenterally or rectally.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7412388A FR2269950B2 (en) | 1974-04-09 | 1974-04-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1445324A true GB1445324A (en) | 1976-08-11 |
Family
ID=9137438
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1208975A Expired GB1445324A (en) | 1974-04-09 | 1975-03-24 | Derivatives of substituted tetrahydro-m-oxazines |
Country Status (11)
Country | Link |
---|---|
JP (1) | JPS50142523A (en) |
BE (1) | BE827650R (en) |
CA (1) | CA1064033A (en) |
CH (1) | CH568997A5 (en) |
DE (1) | DE2513229A1 (en) |
ES (1) | ES436233A2 (en) |
FR (1) | FR2269950B2 (en) |
GB (1) | GB1445324A (en) |
IT (1) | IT1044488B (en) |
LU (1) | LU72236A1 (en) |
NL (1) | NL7504192A (en) |
-
1974
- 1974-04-09 FR FR7412388A patent/FR2269950B2/fr not_active Expired
-
1975
- 1975-03-20 CH CH357575A patent/CH568997A5/xx not_active IP Right Cessation
- 1975-03-24 GB GB1208975A patent/GB1445324A/en not_active Expired
- 1975-03-25 DE DE19752513229 patent/DE2513229A1/en not_active Withdrawn
- 1975-04-02 ES ES436233A patent/ES436233A2/en not_active Expired
- 1975-04-07 BE BE155167A patent/BE827650R/en active
- 1975-04-07 LU LU72236A patent/LU72236A1/xx unknown
- 1975-04-08 JP JP4269175A patent/JPS50142523A/ja active Pending
- 1975-04-08 IT IT6789275A patent/IT1044488B/en active
- 1975-04-08 NL NL7504192A patent/NL7504192A/en unknown
- 1975-04-09 CA CA224,203A patent/CA1064033A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2269950B2 (en) | 1978-07-28 |
DE2513229A1 (en) | 1975-10-30 |
CA1064033A (en) | 1979-10-09 |
JPS50142523A (en) | 1975-11-17 |
IT1044488B (en) | 1980-03-20 |
LU72236A1 (en) | 1976-03-02 |
FR2269950A2 (en) | 1975-12-05 |
NL7504192A (en) | 1975-10-13 |
BE827650R (en) | 1975-10-07 |
ES436233A2 (en) | 1977-03-01 |
CH568997A5 (en) | 1975-11-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |