GB1444552A - Aminoethanols - Google Patents

Aminoethanols

Info

Publication number
GB1444552A
GB1444552A GB5600272A GB5600272A GB1444552A GB 1444552 A GB1444552 A GB 1444552A GB 5600272 A GB5600272 A GB 5600272A GB 5600272 A GB5600272 A GB 5600272A GB 1444552 A GB1444552 A GB 1444552A
Authority
GB
United Kingdom
Prior art keywords
group
dec
formula
aminoethanols
oxazolidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5600272A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Priority to GB5600272A priority Critical patent/GB1444552A/en
Publication of GB1444552A publication Critical patent/GB1444552A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

1444552 N-Disubstituted-2-aminoethanols BEECHAM GROUP Ltd 5 Dec 1973 [5 Dec 1972] 56002/72 Heading C2C Compounds of formula wherein R is a n-propyl or i-butyl group, are obtained by reducing an oxazolidine derivative of formula wherein either (1) R 1 and R 2 are both C 2 H 5 , (2) R 1 =CH 3 and R 2 =n-C 3 H 7 , (3) R 1 =i-C 3 H 7 and R 2 = C 2 H 5 or (4) R 1 = CH 3 and R 2 = i-C 4 H 9 . Preferred reducing systems are hydrogen plus a metal catalyst (e.g. Ni), complex hydrides (e.g. LiAlH 4 or NaBH 4 ) or cyclohexene in the presence of a palladium-on-charcoal catalyst. The oxazolidine starting materials are prepared by reacting a 2-aminoethanol N-substituted by group R 2 with the corresponding aldehyde, R 1 -CHO.
GB5600272A 1972-12-05 1972-12-05 Aminoethanols Expired GB1444552A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB5600272A GB1444552A (en) 1972-12-05 1972-12-05 Aminoethanols

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5600272A GB1444552A (en) 1972-12-05 1972-12-05 Aminoethanols

Publications (1)

Publication Number Publication Date
GB1444552A true GB1444552A (en) 1976-08-04

Family

ID=10475475

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5600272A Expired GB1444552A (en) 1972-12-05 1972-12-05 Aminoethanols

Country Status (1)

Country Link
GB (1) GB1444552A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110987A (en) * 1988-06-17 1992-05-05 Emory University Method of preparing sphingosine derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110987A (en) * 1988-06-17 1992-05-05 Emory University Method of preparing sphingosine derivatives

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee