GB1438151A - Method for the production of a carrier for biologically active compounds - Google Patents

Method for the production of a carrier for biologically active compounds

Info

Publication number
GB1438151A
GB1438151A GB3742773A GB3742773A GB1438151A GB 1438151 A GB1438151 A GB 1438151A GB 3742773 A GB3742773 A GB 3742773A GB 3742773 A GB3742773 A GB 3742773A GB 1438151 A GB1438151 A GB 1438151A
Authority
GB
United Kingdom
Prior art keywords
carrier
primary
acetaminophenoxy
diazotized
biologically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3742773A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Czech Academy of Sciences CAS
Original Assignee
Czech Academy of Sciences CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Czech Academy of Sciences CAS filed Critical Czech Academy of Sciences CAS
Publication of GB1438151A publication Critical patent/GB1438151A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G81/00—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087—Acrylic polymers
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10—Macromolecular compounds

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Dentistry (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pest Control & Pesticides (AREA)
  • Polymers & Plastics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

1438151 Polymeric carriers for enzymes CESKOSLOVENSKA AKADEMIE VED 7 Aug 1973 [18 Aug 1972] 37427/73 Headings C3H and C3P Polymeric carriers for biologically active compounds, e.g. enzymes, are obtained by reacting together (A) the surface of a primary carrier containing reactive groups, which carrier is either a naturally occurring three-dimensional polymer such as wool, silk or collagen, or a water-soluble three-dimensional synthetic polymer derived at least in part from a bi- or multifunctional monomer, and (B) a secondary carrier which is a water-soluble linear polymer containing reactive groups complementary to those of the first carrier and also containing, either initially or by subsequent reaction, active ligands able to bind a biologically active compound. In examples, (1) a primary carrier comprising a hydrolysed and diazotized hydroxyethyl methacrylate/ethylene glycol dimethacrylate/2 - (p - acetaminophenoxy)ethy] methacrylate copolymer is reacted with a secondary carrier comprising a diethylene glycol monomethacrylate/2 - (p - acetaminophenoxy)ethyl methacrylate, and subsequent to reaction the remaining diazo groups on the primary carrier are coupled with #-naphthol, and the secondary carrier is then diazotized; (2) similar to (1) except that after the reaction of the primary and secondary carriers the aminophenyl groups of the latter are mercurated with mercuric acetate; and (3) a primary carrier comprising a hydroxyethyl methacrylate/ethylene glycol dimethacrylate/methacrylanilide copolymer is reacted with a secondary carrier comprising a diazotized diethylene glycol monomethacrylate/2 - (p - acetaminophenoxy) ethyl methacrylate copolymer. Chymotrypsin is bound to the products of above Examples 1 and 3, and papain to the product of Example 2.
GB3742773A 1972-08-18 1973-08-07 Method for the production of a carrier for biologically active compounds Expired GB1438151A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS7200005743A CS179484B1 (en) 1972-08-18 1972-08-18 Method of producing polymeric acrylated or methacrylated carriers of biological active compounds

Publications (1)

Publication Number Publication Date
GB1438151A true GB1438151A (en) 1976-06-03

Family

ID=5402895

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3742773A Expired GB1438151A (en) 1972-08-18 1973-08-07 Method for the production of a carrier for biologically active compounds

Country Status (11)

Country Link
JP (1) JPS49132224A (en)
AT (1) AT334081B (en)
BE (1) BE803716A (en)
CA (1) CA1029490A (en)
CH (1) CH595410A5 (en)
CS (2) CS179484B1 (en)
DE (1) DE2341306A1 (en)
FR (1) FR2196342B1 (en)
GB (1) GB1438151A (en)
NL (1) NL7310963A (en)
SE (2) SE418505B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2849563A1 (en) * 1977-11-14 1979-05-17 Minnesota Mining & Mfg PROTEIN CATCHER

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684728A (en) * 1979-01-12 1987-08-04 Bayer Aktiengesellschaft Solubilizing biologically active compounds with reactive hydrogen atoms
DE2912289A1 (en) * 1979-03-28 1980-10-09 Bayer Ag METHOD FOR IMPROVING THE SOLUBILITY OF BIOLOGICALLY ACTIVE SUBSTANCES IN WATER AND LOWER ALIPHATIC ALCOHOLS, AND NEW COMPOUNDS WITH IMPROVED SOLUBILITY

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1293278A (en) * 1961-05-27 1962-05-11 Improvements to Compositions Containing Enzymes, and to Processes for the Preparation and Use of Such Compositions

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2849563A1 (en) * 1977-11-14 1979-05-17 Minnesota Mining & Mfg PROTEIN CATCHER

Also Published As

Publication number Publication date
CH595410A5 (en) 1978-02-15
CA1029490A (en) 1978-04-11
SE418505B (en) 1981-06-09
FR2196342B1 (en) 1978-11-10
SE421214B (en) 1981-12-07
AU5927073A (en) 1975-02-20
ATA714373A (en) 1976-04-15
DE2341306A1 (en) 1974-02-28
JPS49132224A (en) 1974-12-18
AT334081B (en) 1976-12-27
CS179484B1 (en) 1977-11-30
CS187869B1 (en) 1979-02-28
BE803716A (en) 1973-12-17
NL7310963A (en) 1974-02-20
SE7704506L (en) 1977-04-20
FR2196342A1 (en) 1974-03-15

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee