GB1436831A - Prostaglandins and the preparation thereof - Google Patents
Prostaglandins and the preparation thereofInfo
- Publication number
- GB1436831A GB1436831A GB3200974A GB3200974A GB1436831A GB 1436831 A GB1436831 A GB 1436831A GB 3200974 A GB3200974 A GB 3200974A GB 3200974 A GB3200974 A GB 3200974A GB 1436831 A GB1436831 A GB 1436831A
- Authority
- GB
- United Kingdom
- Prior art keywords
- trans
- hydroxy
- difluoro
- octenyl
- prostaglandins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940094443 oxytocics prostaglandins Drugs 0.000 title abstract 6
- 150000003180 prostaglandins Chemical class 0.000 title abstract 6
- YVHAIVPPUIZFBA-UHFFFAOYSA-N cyclopentaneacetic acid Natural products OC(=O)CC1CCCC1 YVHAIVPPUIZFBA-UHFFFAOYSA-N 0.000 abstract 6
- -1 methoxy, ethoxy, isopropyloxy Chemical group 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 229910052799 carbon Inorganic materials 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000006376 (C3-C10) cycloalkyl group Chemical group 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000004106 butoxy group Chemical group [*]OC([H])([H])C([H])([H])C(C([H])([H])[H])([H])[H] 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5407—Acyclic saturated phosphonium compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38115573A | 1973-07-20 | 1973-07-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1436831A true GB1436831A (en) | 1976-05-26 |
Family
ID=23503911
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3201174A Expired GB1436832A (en) | 1973-07-20 | 1974-07-19 | Prostaglandin intermediates and their preparation |
| GB3200974A Expired GB1436831A (en) | 1973-07-20 | 1974-07-19 | Prostaglandins and the preparation thereof |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3201174A Expired GB1436832A (en) | 1973-07-20 | 1974-07-19 | Prostaglandin intermediates and their preparation |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS5037770A (fr) |
| BE (1) | BE817846R (fr) |
| CH (1) | CH605729A5 (fr) |
| FR (1) | FR2331335A2 (fr) |
| GB (2) | GB1436832A (fr) |
| NL (1) | NL7409778A (fr) |
| ZA (2) | ZA744581B (fr) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2146325A (en) * | 1983-09-07 | 1985-04-17 | Erba Farmitalia | 16-Fluoro-16,17-didehydro prostanoids and process for their preparation |
| US4642724A (en) * | 1982-06-22 | 1987-02-10 | S&C Electric Company | Trip signal generator for a circuit interrupter |
| WO2002094274A1 (fr) * | 2001-05-18 | 2002-11-28 | Sucampo Ag | Composition cathartique |
-
1974
- 1974-07-17 ZA ZA00744581A patent/ZA744581B/xx unknown
- 1974-07-17 JP JP49081239A patent/JPS5037770A/ja active Pending
- 1974-07-17 ZA ZA00744580A patent/ZA744580B/xx unknown
- 1974-07-19 GB GB3201174A patent/GB1436832A/en not_active Expired
- 1974-07-19 FR FR7425285A patent/FR2331335A2/fr active Granted
- 1974-07-19 NL NL7409778A patent/NL7409778A/xx not_active Application Discontinuation
- 1974-07-19 GB GB3200974A patent/GB1436831A/en not_active Expired
- 1974-07-19 CH CH999374A patent/CH605729A5/xx not_active IP Right Cessation
- 1974-07-19 BE BE146727A patent/BE817846R/fr active
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4642724A (en) * | 1982-06-22 | 1987-02-10 | S&C Electric Company | Trip signal generator for a circuit interrupter |
| GB2146325A (en) * | 1983-09-07 | 1985-04-17 | Erba Farmitalia | 16-Fluoro-16,17-didehydro prostanoids and process for their preparation |
| WO2002094274A1 (fr) * | 2001-05-18 | 2002-11-28 | Sucampo Ag | Composition cathartique |
| US6956056B2 (en) | 2001-05-18 | 2005-10-18 | Sucampo Ag | Method for providing a cathartic effect |
| AU2002307725B2 (en) * | 2001-05-18 | 2008-07-10 | Sucampo Ag | Cathartic composition |
| US7459583B2 (en) | 2001-05-18 | 2008-12-02 | Sucampo Ag | Method for providing a cathartic effect |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7409778A (nl) | 1975-01-22 |
| FR2331335A2 (fr) | 1977-06-10 |
| BE817846R (fr) | 1975-01-20 |
| GB1436832A (en) | 1976-05-26 |
| JPS5037770A (fr) | 1975-04-08 |
| FR2331335B2 (fr) | 1979-05-25 |
| ZA744580B (en) | 1975-07-30 |
| CH605729A5 (fr) | 1978-10-13 |
| ZA744581B (en) | 1975-07-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |