GB1436670A - Preparation of alpha-6-deoxy-5-oxytetracycline - Google Patents

Preparation of alpha-6-deoxy-5-oxytetracycline

Info

Publication number
GB1436670A
GB1436670A GB2545174A GB2545174A GB1436670A GB 1436670 A GB1436670 A GB 1436670A GB 2545174 A GB2545174 A GB 2545174A GB 2545174 A GB2545174 A GB 2545174A GB 1436670 A GB1436670 A GB 1436670A
Authority
GB
United Kingdom
Prior art keywords
deoxy
oxytetracycline
group
oxytetracyline
isomer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2545174A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of GB1436670A publication Critical patent/GB1436670A/en
Expired legal-status Critical Current

Links

Classifications

    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Abstract

1436670 α - 6 - Deoxy - 5 - oxytetracyline CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA RT 7 June 1974 [8 June 1973] 25451/74 Heading C2C [Also in Division B1] α - 6 - Deoxy - 5 - hydroxy - tetracyline or a salt thereof is prepared by hydrogenating a compound I in which X is hydrogen, chlorine, bromine or iodine or a salt thereof in the presence of an alloy catalyst which contains at least one noble metal of Group VIII of the Periodic Table with at least one metal selected from Group Ib. The catalyst is supported on activated carbon silica or alumina. The method yields the α-isomer in preference to the #-isomer; the reaction in the absence of a Group Ib metal yields a mixture of starting material, 5a,6-anhydro-oxytetracyline and α-apo-oxytetracycline.
GB2545174A 1973-06-08 1974-06-07 Preparation of alpha-6-deoxy-5-oxytetracycline Expired GB1436670A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI1387A HU167250B (en) 1973-06-08 1973-06-08

Publications (1)

Publication Number Publication Date
GB1436670A true GB1436670A (en) 1976-05-19

Family

ID=10994484

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2545174A Expired GB1436670A (en) 1973-06-08 1974-06-07 Preparation of alpha-6-deoxy-5-oxytetracycline

Country Status (12)

Country Link
JP (1) JPS5052051A (en)
AT (1) AT332969B (en)
BE (1) BE816029A (en)
CS (1) CS175748B1 (en)
DD (1) DD113894A1 (en)
DK (1) DK307174A (en)
ES (1) ES427070A1 (en)
FR (1) FR2232539A1 (en)
GB (1) GB1436670A (en)
HU (1) HU167250B (en)
PL (1) PL93707B1 (en)
SU (1) SU632298A3 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102086165A (en) * 2010-12-29 2011-06-08 开封制药(集团)有限公司 Application of Pd catalyst in hydrogenation process for producing doxycycline

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK386784A (en) * 1983-08-17 1985-02-18 Hovione Int Ltd PROCEDURE FOR PREPARING ALFA-6-DESOXY-TETRACYCLINES
HU198173B (en) * 1987-09-18 1989-08-28 Chinoin Gyogyszer Es Vegyeszet Process for producing doxycycline
ATE68476T1 (en) * 1989-04-03 1991-11-15 Ranbaxy Lab Ltd PROCESS FOR THE PRODUCTION OF ALPHA-6DEOXYTETRACYCLINES.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102086165A (en) * 2010-12-29 2011-06-08 开封制药(集团)有限公司 Application of Pd catalyst in hydrogenation process for producing doxycycline
CN102086165B (en) * 2010-12-29 2013-06-19 开封制药(集团)有限公司 Application of Pd catalyst in hydrogenation process for producing doxycycline

Also Published As

Publication number Publication date
ES427070A1 (en) 1976-07-16
FR2232539A1 (en) 1975-01-03
PL93707B1 (en) 1977-06-30
DD113894A1 (en) 1975-07-05
ATA457574A (en) 1976-02-15
SU632298A3 (en) 1978-11-05
CS175748B1 (en) 1977-05-31
DK307174A (en) 1975-02-03
BE816029A (en) 1974-09-30
JPS5052051A (en) 1975-05-09
HU167250B (en) 1975-09-27
AT332969B (en) 1976-10-25

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Legal Events

Date Code Title Description
PS Patent sealed
435 Patent endorsed 'licences of right' on the date specified (sect. 35/1949)
PCNP Patent ceased through non-payment of renewal fee