GB1431888A - Separation apparatus - Google Patents

Separation apparatus

Info

Publication number
GB1431888A
GB1431888A GB867875A GB867875A GB1431888A GB 1431888 A GB1431888 A GB 1431888A GB 867875 A GB867875 A GB 867875A GB 867875 A GB867875 A GB 867875A GB 1431888 A GB1431888 A GB 1431888A
Authority
GB
United Kingdom
Prior art keywords
migrant
chamber
inlet
outlet
fractions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB867875A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UK Atomic Energy Authority
Original Assignee
UK Atomic Energy Authority
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UK Atomic Energy Authority filed Critical UK Atomic Energy Authority
Priority to GB867875A priority Critical patent/GB1431888A/en
Publication of GB1431888A publication Critical patent/GB1431888A/en
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D43/00—Separating particles from liquids, or liquids from solids, otherwise than by sedimentation or filtration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Electrochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • External Artificial Organs (AREA)

Abstract

1431888 Electro-phoretic separation UNITED KINGDOM ATOMIC ENERGY AUTHORITY 21 Aug 1973 [6 Sept 1972] 8678/75 Divided out of 1431887 Heading C7B An electro-phoretic separation apparatus comprises an annular separation chamber 6 bonded by coaxial outer and inner walls e.g. of cylindrical rotor 5 and stator 1 which rotate relatively (at least the outer wall rotating e.g. by rotor drive-shaft 7) about a common axis to stabilize flow conditions, inlet means e.g. tube 29 and orifice 31 for introducing migrant material and a migrant-supporting fluid into the chamber, outlet means 9 for selectively removing the supporting fluid with or without separated migrant fractions from the chamber e.g. through end-piece 10, and means for generating a radial force field to separate migrant material into fractions, e.g. cathode and anode systems 11, 16 each comprising an electrolyte compartment 12, 19 with inlet and outlet tubes 17, 22 and 18, 23 and bounded by stainless steel cathode/anode 13, 20 and porous resin bonded matrix tube 14, 21 supporting cellulose membrane 15, 15a permeable to ions, as disclosed in Specification no 1186184. The migrant material is supplied as disclosed in Specification 1431887. The separated fraction is conducted from a plurality of collecting chamber inlets 33 (only one shown), Fig. 4 (not shown) along a plurality of non-linear paths via inter-connected channels 38, Fig. 5 (not shown) to converge at outlet 34 within each collecting chamber; the minimum path length from all points on the inlet 33 being the same; the collecting chambers may be constituted by a stacked plurality of plates 36 with central orifice 37, spaced by washers 32. The catholyte and anolyte fed into compartments 12, 19 may be respectively ammonium acetate and ammonium phosphate solution. The carrier buffer passed up through chamber 6 may be a solution of tris (hydroxymethyl) aminomethane citrate, and the migrant fluid dialysed against the buffer solution may be a bovine blood serum.
GB867875A 1972-09-06 1972-09-06 Separation apparatus Expired GB1431888A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB867875A GB1431888A (en) 1972-09-06 1972-09-06 Separation apparatus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB867875A GB1431888A (en) 1972-09-06 1972-09-06 Separation apparatus

Publications (1)

Publication Number Publication Date
GB1431888A true GB1431888A (en) 1976-04-14

Family

ID=9857120

Family Applications (1)

Application Number Title Priority Date Filing Date
GB867875A Expired GB1431888A (en) 1972-09-06 1972-09-06 Separation apparatus

Country Status (1)

Country Link
GB (1) GB1431888A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1979000299A1 (en) * 1977-11-17 1979-05-31 Atomic Energy Authority Uk Purification of factor viii
DE3004138A1 (en) * 1979-02-16 1980-08-28 Atomic Energy Authority Uk METHOD FOR FRACTIONING SOLUTIONS CONTAINING IMMUNOBULIN
EP0062456A2 (en) * 1981-04-08 1982-10-13 United Kingdom Atomic Energy Authority Blood fractionation improvement

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1979000299A1 (en) * 1977-11-17 1979-05-31 Atomic Energy Authority Uk Purification of factor viii
DE2857166C2 (en) * 1977-11-17 1988-05-11 United Kingdom Atomic Energy Authority, London, Gb
DE3004138A1 (en) * 1979-02-16 1980-08-28 Atomic Energy Authority Uk METHOD FOR FRACTIONING SOLUTIONS CONTAINING IMMUNOBULIN
US4246085A (en) 1979-02-16 1981-01-20 United Kingdom Atomic Energy Authority Fractionation of proteins
EP0062456A2 (en) * 1981-04-08 1982-10-13 United Kingdom Atomic Energy Authority Blood fractionation improvement
EP0062456A3 (en) * 1981-04-08 1985-01-30 United Kingdom Atomic Energy Authority Blood fractionation improvement

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Legal Events

Date Code Title Description
PS Patent sealed
429A Application made for amendment of specification (sect. 29/1949)
429H Application (made) for amendment of specification now open to opposition (sect. 29/1949)
429D Case decided by the comptroller ** specification amended (sect. 29/1949)
SP Amendment (slips) printed
PCNP Patent ceased through non-payment of renewal fee