GB1428598A - Process for the manufacture of 1,3-bis- beta-ethylhexyl- 5-amino-5-methyl-hexahydropyrimidine and a derivative of the 5-nitro analogue thereof - Google Patents

Process for the manufacture of 1,3-bis- beta-ethylhexyl- 5-amino-5-methyl-hexahydropyrimidine and a derivative of the 5-nitro analogue thereof

Info

Publication number
GB1428598A
GB1428598A GB4824374A GB4824374A GB1428598A GB 1428598 A GB1428598 A GB 1428598A GB 4824374 A GB4824374 A GB 4824374A GB 4824374 A GB4824374 A GB 4824374A GB 1428598 A GB1428598 A GB 1428598A
Authority
GB
United Kingdom
Prior art keywords
base
nitro
amino
hexahydropyrimidine
nov
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4824374A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MEDITEST INST fur MEDIZINISCH
Original Assignee
MEDITEST INST fur MEDIZINISCH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MEDITEST INST fur MEDIZINISCH filed Critical MEDITEST INST fur MEDIZINISCH
Publication of GB1428598A publication Critical patent/GB1428598A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/04—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

1428598 Hexahydropyrimidine derivatives MEDITEST INSTITUT FUR MEDIZINISCH PHARMAZEUTISCHE UNTERSUCHUNGEN GmbH 7 Nov 1974 [8 Nov 1973] 48243/74 Heading C2C The invention comprises the compound of formula and a process for making it in which to an aqueous alcoholic solution of crude nitro-base (obtained by reacting BuEtCHCH 2 NH 2 with CH 2 O followed by EtNO 2 ) is added naphthalene-1,5-disulphonic acid, and the selectively precipitated salt is separated off. The purified nitro-base, formed by treating the salt with alkali, may be hydrogenated to give the analogous amino-base in a pure state. Biocidal and pharmaceutical compositions comprise the nitro-compound of the above formula, or the corresponding amino-base. The former is stated to have fungicidal and bactericidal activity, and the latter antimicrobial, antiseptic and insecticidal activity.
GB4824374A 1973-11-08 1974-11-07 Process for the manufacture of 1,3-bis- beta-ethylhexyl- 5-amino-5-methyl-hexahydropyrimidine and a derivative of the 5-nitro analogue thereof Expired GB1428598A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732355917 DE2355917C3 (en) 1973-11-08 1973-11-08 1,3-bis (β-ethylhexyl) -5-nitro-5-methyl-hexahydropyrimidine-naphthalene-1,5-disulfonate and process for its preparation

Publications (1)

Publication Number Publication Date
GB1428598A true GB1428598A (en) 1976-03-17

Family

ID=5897575

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4824374A Expired GB1428598A (en) 1973-11-08 1974-11-07 Process for the manufacture of 1,3-bis- beta-ethylhexyl- 5-amino-5-methyl-hexahydropyrimidine and a derivative of the 5-nitro analogue thereof

Country Status (6)

Country Link
AT (1) AT340935B (en)
CH (1) CH601256A5 (en)
DE (1) DE2355917C3 (en)
ES (1) ES431788A1 (en)
GB (1) GB1428598A (en)
NL (1) NL7414613A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2549733C2 (en) * 1975-11-06 1986-07-31 Dolorgiet GmbH & Co KG, 5205 St Augustin 1,3-Bis - (β-ethylhexyl) -5-amino-5-methyl-hexahydropyrimidine terephthalate, process for its preparation and pharmaceutical compositions containing it
DE2624980C2 (en) * 1976-06-03 1986-12-11 Dolorgiet GmbH & Co KG, 5205 St Augustin Salts of 1,3-bis (β-aethyl-hexyl) -5-amino-5-methyl-hexahydropyrimidine, process for their preparation and medicinal preparations containing them

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2011078C3 (en) * 1970-03-09 1974-11-14 Goedecke Ag, 1000 Berlin Process for purifying hexetidine

Also Published As

Publication number Publication date
ATA892574A (en) 1977-05-15
AT340935B (en) 1978-01-10
ES431788A1 (en) 1977-03-16
DE2355917B2 (en) 1978-03-16
DE2355917C3 (en) 1983-04-21
DE2355917A1 (en) 1975-05-15
NL7414613A (en) 1975-05-12
CH601256A5 (en) 1978-06-30

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee