GB1426657A - Method for preparation of a dry cyanogen bromide activated hydrophilic polymeric carrier of biologically active compounds - Google Patents

Method for preparation of a dry cyanogen bromide activated hydrophilic polymeric carrier of biologically active compounds

Info

Publication number
GB1426657A
GB1426657A GB297174A GB297174A GB1426657A GB 1426657 A GB1426657 A GB 1426657A GB 297174 A GB297174 A GB 297174A GB 297174 A GB297174 A GB 297174A GB 1426657 A GB1426657 A GB 1426657A
Authority
GB
United Kingdom
Prior art keywords
biologically active
active compounds
cyanogen bromide
preparation
polymeric carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB297174A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Czech Academy of Sciences CAS
Original Assignee
Czech Academy of Sciences CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Czech Academy of Sciences CAS filed Critical Czech Academy of Sciences CAS
Priority to GB297174A priority Critical patent/GB1426657A/en
Publication of GB1426657A publication Critical patent/GB1426657A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/18—Introducing halogen atoms or halogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087—Acrylic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/098—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer formed in the presence of the enzymes or microbial cells

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

1426657 Polymeric carriers; insolubilized enzymes CESKOSLOVENSKA AKADEMIE VED 22 Jan 1974 02971/74 Headings C3H and C3P Carriers for biologically active compounds, e.g. chymotrypsin, are made by (1) suspension copolymerization of a hydroxy ester of acrylic or methacrylic acid with a cross-linking monomer selected from divinyl benzene, bisacrylamides, bismethacrylamides, and acrylate and methacrylate esters of bi- or tri-functional alcohols, (2) activation of the resulting gel polymer by reaction of hydroxy groups with cyanogen bromide, and (3) removal of water from the product, e.g. by solvent treatment of vacuum distillation at below freezing temperature. In examples, the carrier comprises an activated 2-hydroxyethyl methacrylate/ethylene glycol dimethacrylate copolymer.
GB297174A 1974-01-22 1974-01-22 Method for preparation of a dry cyanogen bromide activated hydrophilic polymeric carrier of biologically active compounds Expired GB1426657A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB297174A GB1426657A (en) 1974-01-22 1974-01-22 Method for preparation of a dry cyanogen bromide activated hydrophilic polymeric carrier of biologically active compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB297174A GB1426657A (en) 1974-01-22 1974-01-22 Method for preparation of a dry cyanogen bromide activated hydrophilic polymeric carrier of biologically active compounds

Publications (1)

Publication Number Publication Date
GB1426657A true GB1426657A (en) 1976-03-03

Family

ID=9749496

Family Applications (1)

Application Number Title Priority Date Filing Date
GB297174A Expired GB1426657A (en) 1974-01-22 1974-01-22 Method for preparation of a dry cyanogen bromide activated hydrophilic polymeric carrier of biologically active compounds

Country Status (1)

Country Link
GB (1) GB1426657A (en)

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee