GB1486288A - Hydrophobic substrates having grafted hydrophilic inclusions containing polar soluble substances - Google Patents

Hydrophobic substrates having grafted hydrophilic inclusions containing polar soluble substances

Info

Publication number
GB1486288A
GB1486288A GB47545/74A GB4754574A GB1486288A GB 1486288 A GB1486288 A GB 1486288A GB 47545/74 A GB47545/74 A GB 47545/74A GB 4754574 A GB4754574 A GB 4754574A GB 1486288 A GB1486288 A GB 1486288A
Authority
GB
United Kingdom
Prior art keywords
soluble substances
containing polar
hydrophobic substrates
inclusions containing
grafted hydrophilic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB47545/74A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA filed Critical Commissariat a lEnergie Atomique CEA
Publication of GB1486288A publication Critical patent/GB1486288A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F291/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0081—After-treatment of organic or inorganic membranes
    • B01D67/0093—Chemical modification
    • B01D67/00931—Chemical modification by introduction of specific groups after membrane formation, e.g. by grafting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/14—Dynamic membranes
    • B01D69/141—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/12—Chemical modification
    • C08J7/16—Chemical modification with polymerisable compounds
    • C08J7/18—Chemical modification with polymerisable compounds using wave energy or particle radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/38—Graft polymerization

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Inorganic Chemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Dispersion Chemistry (AREA)
  • Transplantation (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Graft Or Block Polymers (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

1486288 Sustained release of medicaments COMMISSARIAT A L'ENERGIE ATOMIQUE 4 Nov 1974 [9 Nov 1973] 47545/74 Heading A5B [Also in Division C3] A hydrophobic polymeric substrate has cross-linked polymerised hydrophilic inclusions derived from an hydrophilic ethylenically unsaturated monomer grafted to the substrate and distributed throughout the volume thereof and has a medicament, soluble in polar solvents, stored in said inclusions and desorbable therefrom on contacting the hydrophobic polymeric substrate with a polar solvent.
GB47545/74A 1973-11-09 1974-11-04 Hydrophobic substrates having grafted hydrophilic inclusions containing polar soluble substances Expired GB1486288A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7340002A FR2250793B1 (en) 1973-11-09 1973-11-09

Publications (1)

Publication Number Publication Date
GB1486288A true GB1486288A (en) 1977-09-21

Family

ID=9127552

Family Applications (1)

Application Number Title Priority Date Filing Date
GB47545/74A Expired GB1486288A (en) 1973-11-09 1974-11-04 Hydrophobic substrates having grafted hydrophilic inclusions containing polar soluble substances

Country Status (14)

Country Link
JP (1) JPS5639780B2 (en)
BE (1) BE821909A (en)
CA (1) CA1049954A (en)
CH (1) CH606208A5 (en)
DE (1) DE2453155C2 (en)
ES (1) ES431778A1 (en)
FR (1) FR2250793B1 (en)
GB (1) GB1486288A (en)
IL (1) IL46010A (en)
IT (1) IT1024789B (en)
NL (1) NL164874C (en)
SE (1) SE419967B (en)
SU (1) SU1060119A3 (en)
ZA (1) ZA747123B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2186485A (en) * 1986-02-13 1987-08-19 Ethical Generics Ltd Slow release formulation
EP0272841A2 (en) * 1986-12-23 1988-06-29 Pall Corporation Filtration media
US4894238A (en) * 1979-03-21 1990-01-16 National Research Development Corporation Controlled release compositions
US4959150A (en) * 1988-09-26 1990-09-25 Pall Corporation Fluid treatment system having low affinity for proteinaceous materials
US5342624A (en) * 1989-02-16 1994-08-30 British Technology Group Ltd. Dispensing device

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2311792A1 (en) * 1975-05-20 1976-12-17 Anvar Acrylic acid grafted PVC sheet - used for selectively permeable membrane
JPS5477661A (en) * 1977-12-02 1979-06-21 Teijin Ltd Crosslinked or uncrosslinked linear aromatic polyester composition and its production
FR2433949A1 (en) * 1978-08-25 1980-03-21 Commissariat Energie Atomique HYDROPHOBIC SUBSTRATE CAPABLE OF RELEASING A CHEMICAL SUBSTANCE
DE2930321A1 (en) * 1978-09-25 1980-04-10 Jenapharm Veb METHOD FOR PRODUCING A NEW PHARMACEUTICAL AUXILIARY SUBSTANCE AND SOLID MEDICINES PRODUCED THEREOF
ATE24550T1 (en) * 1980-01-29 1987-01-15 Atochem DIAPHRAGM FOR ELECTROLYSIS AND PROCESS FOR ITS MANUFACTURE.
FR2485370A1 (en) * 1980-06-30 1981-12-31 Commissariat Energie Atomique INERTE SUPPORT IN RETICULATED COPOLYMER, METHOD FOR PREPARING THE SAME AND USE THEREOF FOR PRODUCING DELAYED MEDICAMENTS
FR2505879B1 (en) * 1981-05-15 1985-09-27 Chloe Chemie DIAPHRAGM, ITS PREPARATION METHOD AND THE ELECTROLYSIS METHOD USING THE SAME
FR2513256A1 (en) * 1981-09-18 1983-03-25 Commissariat Energie Atomique ELASTOMER SEPARATOR ELEMENT, PROCESS FOR PREPARING THE SAME AND USE THEREOF IN HYDROPNEUMATIC SUSPENSION SYSTEMS
JPS5969570U (en) * 1982-10-29 1984-05-11 日本電気ホームエレクトロニクス株式会社 display device
US4695592A (en) * 1986-01-07 1987-09-22 Mitsubishi Rayon Co., Ltd. Hydrophilized porous membrane and production process thereof
US4897433A (en) * 1986-12-08 1990-01-30 Japan Atomic Energy Research Inst. Process for producing an anti-thrombogenic material by graft polymerization
AU608315B2 (en) * 1987-01-28 1991-03-28 Membrex, Inc. Hydrophilic article and method of producing same
WO1989004198A1 (en) * 1987-11-04 1989-05-18 Mitsubishi Rayon Co., Ltd. Porous membrane and process for its production
DE4117281C2 (en) * 1990-06-29 1996-02-22 Gore Enterprise Holdings Inc Hydrophilized, microporous membrane made of polytetrafluoroethylene and process for its production
JP2725094B2 (en) * 1991-07-30 1998-03-09 東燃化学株式会社 Separation membrane, method for producing the same and separation method
FR2699406B1 (en) * 1992-12-21 1995-03-10 Commissariat Energie Atomique Films based on copolymers, their applications in transdermal systems and their preparation processes.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2056057A5 (en) * 1969-08-26 1971-05-14 Raffinage Cie Francaise
JPS4934302A (en) * 1972-07-27 1974-03-29

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894238A (en) * 1979-03-21 1990-01-16 National Research Development Corporation Controlled release compositions
US4931288A (en) * 1979-03-21 1990-06-05 Lloyds Bank Plc Controlled release compositions (II)
GB2186485A (en) * 1986-02-13 1987-08-19 Ethical Generics Ltd Slow release formulation
US4880830A (en) * 1986-02-13 1989-11-14 Ethical Pharmaceuticals Limited Slow release formulation
EP0272841A2 (en) * 1986-12-23 1988-06-29 Pall Corporation Filtration media
GB2199331A (en) * 1986-12-23 1988-07-06 Pall Corp Porous polymeric filtration media
EP0272841A3 (en) * 1986-12-23 1988-11-30 Pall Corporation Filtration media
US4906374A (en) * 1986-12-23 1990-03-06 Pall Corporation Filtration media with low protein adsorbability
GB2199331B (en) * 1986-12-23 1990-07-11 Pall Corp Filtration media
US4959150A (en) * 1988-09-26 1990-09-25 Pall Corporation Fluid treatment system having low affinity for proteinaceous materials
US5342624A (en) * 1989-02-16 1994-08-30 British Technology Group Ltd. Dispensing device

Also Published As

Publication number Publication date
IL46010A0 (en) 1975-05-22
FR2250793B1 (en) 1978-12-29
CH606208A5 (en) 1978-10-31
CA1049954A (en) 1979-03-06
FR2250793A1 (en) 1975-06-06
NL164874B (en) 1980-09-15
SU1060119A3 (en) 1983-12-07
ES431778A1 (en) 1977-05-16
IT1024789B (en) 1978-07-20
DE2453155A1 (en) 1975-05-15
DE2453155C2 (en) 1986-01-30
NL164874C (en) 1981-02-16
JPS5639780B2 (en) 1981-09-16
IL46010A (en) 1978-09-29
SE419967B (en) 1981-09-07
BE821909A (en) 1975-03-03
NL7414588A (en) 1975-05-13
ZA747123B (en) 1976-03-31
JPS50112479A (en) 1975-09-03
SE7414081L (en) 1976-05-10

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PE20 Patent expired after termination of 20 years

Effective date: 19941103